A5026292678- Asthma and respiratory diseases
- Viral gastroenteritis research and epidemiology
- IL-33, ST2, and ILC Pathways
- Congenital Diaphragmatic Hernia Studies
- Geomagnetism and Paleomagnetism Studies
- Respiratory Support and Mechanisms
- Hip and Femur Fractures
- Public Health in Brazil
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Laser-induced spectroscopy and plasma
- Virus-based gene therapy research
- Orthopaedic implants and arthroplasty
- Hip disorders and treatments
- Mycobacterium research and diagnosis
- Immune Cell Function and Interaction
- Neonatal Respiratory Health Research
- Respiratory and Cough-Related Research
- Muscle Physiology and Disorders
- Intensive Care Unit Cognitive Disorders
- Eosinophilic Esophagitis
- Mental Health and Psychiatry
- Orthodontics and Dentofacial Orthopedics
- Facial Nerve Paralysis Treatment and Research
- Medical Education and Admissions
- Frailty in Older Adults
Yale University
2021-2025
Johns Hopkins University
2016-2024
University of California, San Francisco
2024
University of California System
2024
Brazilian Research in Intensive Care Network
2023
ENT and Allergy
2023
Washington State University
2021
Pioneer (United States)
2021
University of Oxford
2021
Children's Hospital at Montefiore
2020
Understanding magnetic-field generation and amplification in turbulent plasma is essential to account for observations of magnetic fields the universe. A theoretical framework attributing origin sustainment these so-called fluctuation dynamo was recently validated by experiments on laser facilities low-magnetic-Prandtl-number plasmas ([Formula: see text]). However, same proposes that should operate differently when [Formula: text], regime relevant many astrophysical environments such as...
Pediatric obesity-related asthma is characterized by non-atopic T helper 1 (Th1) inflammation and steroid resistance. CDC42 upregulation in CD4 + cells underlies Th1 but the cell subtype(s) with their contribution to resistance are not known. Compared healthy-weight asthma, obesity-alone controls, single-cell transcriptomics of obese revealed 3 clusters comprised naïve central memory cells, which differed from cluster enriched for responses that was effector cells. NR3C1, coding...
Pediatric obesity-related asthma is characterized by non-atopic T helper 1 (Th1) inflammation and steroid resistance. CDC42 upregulation in CD4+T cells underliesTh1 but the cell subtype(s) with their contribution to resistance are not known. Compared healthy-weight asthma, obesity-alone controls, single-cell transcriptomics of obese revealed
Aging | doi:10.18632/aging.100929. Qian-Li Xue, Huanle Yang, Hui-Fen Li, Peter M. Abadir, Tyesha N. Burks, Lauren G. Koch, Steven L. Britton, Joshua Carlson, Laura Chen, Jeremy D. Walston, Sean X. Leng
Shigella is a leading cause of moderate-to-severe diarrhea globally and the causative agent shigellosis bacillary dysentery. Associated with 80 to 165 million cases >13% diarrheal deaths, in many regions, exposure ubiquitous while infection heterogenous. To characterize host-genetic susceptibility Shigella-associated diarrhea, we performed two independent genome-wide association studies (GWAS) including Bangladeshi infants from PROVIDE CBC birth cohorts Dhaka, Bangladesh. Cases were (n =...
Abstract Background Climate change poses significant health risks, with children being particularly vulnerable to its adverse effects. Children asthma are expected have worsening disease due increased exposure heat, air pollution, mold from flooding, and pollen. Understanding caregiver perspectives on these harms is crucial for informing public policy education. Therefore, we aimed explore perceptions of climate change‐related risks asthma. Methods In this cross‐sectional study, a survey...
Objetivos: avaliar os cuidados de enfermagem relacionados ao cateter venoso central (CVC) em uma unidade Terapia Intensiva adulto e pediátrica, comparar a conduta protocolo padronizado na instituição analisar resultados baseando-se no manual da Agência Nacional Vigilância 2017. Metodologia: trata-se auditoria clínica realizada um hospital público Minas Gerais. Foram selecionados pacientes portadores CVC, internados leito par período junho julho 2017 setor. Os dados foram coletados através do...
Pulmonary complications are the leading cause of morbidity and mortality in sickle cell disease (SCD) patients. Research SCD has predominantly been conducted on African-Americans, burden other races ethnicities, including Hispanic patients, is not well characterized.To compare pulmonary between non-Hispanic ethnic groups among children with SCD.In a retrospective chart review 566 patients followed at Children's Hospital Montefiore, NY, we compared management to their counterparts. We also...
Objective Fractional exhaled nitric oxide (FeNO) is a well-established measure of allergic airway inflammation and possible useful adjunct disease management tool. We investigated the association baseline follow-up FeNO measurements with burden in minority children persistent asthma.Methods A retrospective chart review was conducted on 352 African American Hispanic seen at an urban Asthma Center Bronx, NY. Demographic, clinical characteristics, pulmonary function tests (PFTs) were compared...
The authors declare no conflict of interest. data that supports the findings this study are available in supplementary material article. Please note: publisher is not responsible for content or functionality any supporting information supplied by authors. Any queries (other than missing content) should be directed to corresponding author
Abstract Background Astroviral infections commonly cause acute nonbacterial gastroenteritis in children globally. However, these often go undiagnosed outside of research settings. There is no treatment available for astrovirus, and Astroviridae strain diversity presents a challenge to potential vaccine development. Methods To address our hypothesis that host genetic risk factors are associated with astrovirus disease susceptibility, we performed genome-wide association study infection the...
Motivation: Hip abductor muscles have a fundamental role in walking and other daily physical tasks. Relating hip muscle fat fractions to patient-reported outcomes at later timepoint could provide insights on exercise targets for patients with osteoarthritis who may become candidates total arthroplasty. Goal(s): The study seeks determine if predict after 4 years. Approach: Linear mixed-effects regressions were performed investigate relationships between baseline PROMS follow-up. Results:...
Introduction: Bronchopulmonary dysplasia (BPD) is a chronic lung disorder affecting many premature infants. Infants with BPD have higher hospital readmission rates due to respiratory-related morbidity. We aimed increase the of outpatient pulmonary follow-up and attendance babies moderate severe above 85% within 6 months. Methods: conducted quality improvement project at Yale New Haven Children’s Hospital. Key interventions included developing clinical pathway integrated into electronic...
Background Bullous amyloidosis is a rare disease in humans that has not been described veterinary species the peer‐reviewed literature. The human characterised by haemorrhagic vesicles and bullae on skin mucosae, which form due to amyloid deposition. Hypothesis/Objectives To describe clinical features, laboratory analysis histopathological features of an unique presentation bullous horse. Animals A 17‐year‐old thoroughbred mare presented for weight loss severe oral cavity ulcers. Methods...
Abstract Astroviral infections commonly cause acute nonbacterial gastroenteritis in children globally. However, these often go undiagnosed outside of research settings. There is no treatment available for astrovirus, and Astroviridae strain diversity presents a challenge to potential vaccine development. To address our hypothesis that host genetic risk factors are associated with astrovirus disease susceptibility, we performed genome-wide association study (GWAS) infection the first year...