A5058037237- Global Cancer Incidence and Screening
- COVID-19 and healthcare impacts
- Hippo pathway signaling and YAP/TAZ
- BRCA gene mutations in cancer
- Economic and Financial Impacts of Cancer
- Cancer Genomics and Diagnostics
- Genetic factors in colorectal cancer
Seoul St. Mary's Hospital
2024-2025
Catholic University of Korea
2024-2025
St. Mary’s Hospital
2020
<title>Abstract</title> Recent advancements in genomic technologies have become critical tools for deciphering the genetic complexities of cancer tissues, enabling precision medicine strategies aimed at improving patient clinical outcomes. Here we performed a comprehensive analysis clinically annotated whole genome and transcriptome sequences from 1,364 breast cases. Our investigation provides most detailed landscapes to date, which allowed us comprehensively correlate changes with...
Abstract Background: Yes-associated protein 1 (YAP1) is a transcription factor regulated by the Hippo pathway and functions as an oncogene in various solid tumors under dysregulated pathway. However, role of YAP1 breast cancer controversial. Here, we investigated impact different levels nuclear expression on clinical characteristics survival outcome patients with cancer. Patients Methods: Retrospectively obtained 469 tumor samples at Gangnam Severance Hospital were examined for...