A5072677798- Infant Development and Preterm Care
- Infant Nutrition and Health
- Clinical Nutrition and Gastroenterology
- Antioxidant Activity and Oxidative Stress
- Food Quality and Safety Studies
- Pancreatitis Pathology and Treatment
- Genetics and Neurodevelopmental Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Pancreatic and Hepatic Oncology Research
Yokohama University of Pharmacy
2019-2020
Mayo Clinic in Arizona
1998
alpha-Carotene inhibited the proliferation of human neuroblastoma cell line GOTO in a dose- and time-dependent manner. In addition, it was about 10 times more inhibitory than beta-carotene. Northern blot analysis indicated that alpha-carotene caused maximum suppression level N-myc messenger RNA cells. This occurred within 18 hours treatment, after which gradually recovered to basal level. Analysis by flow cytometry when cells were exposed alpha-carotene, they arrested G0-G1 phase their...
Background: Decreases in female hormones not only affect bone metabolism and decrease mass, but also the central nervous system, causing brain disorders such as depression dementia. Administration of estradiol by hormone replacement therapy can improve dementia, while reduced ovariectomized (OVX) model rats reduce both density locomotor activity. The antidepressant fluvoxamine, which is widely used clinical practice, this effect on reduction. Similarly, lactoferrin (LF) reportedly inhibitory...
Lactoferrin (LF) is a protein that rich in breast milk. Recently, it reported LF associated with memory and affection to improve cognitive function. Thus, we examined the effect of on neurite outgrowth rat adrenal pheochromocytoma PC12 cells, this study. Moreover, cAMP response element-binding (CREB) inhibitor, KG-501 (KG;5mM) was added onto PC12cells treated LF. In addition, RNA expression level Neurofilament light(NF-L) measured by Real-time PCR. cells seeded 12-well plate...
Coriandrum sativum (CS) has been used as folk remedies for Ebers papyrus, an ancient medical record in Egypt over 3000 years. It reported that CS shows the effects of antioxidant and anti-inflammatory. In this study, we examined protective role leaf extract (CSLE) against cytotoxicity induced by hydrogen peroxide (H2O2) on neurite outgrowth PC12 cells.