A5025479694- Toxin Mechanisms and Immunotoxins
- Plant tissue culture and regeneration
- Complementary and Alternative Medicine Studies
- Long-Term Effects of COVID-19
- Polyomavirus and related diseases
- Transgenic Plants and Applications
- Acupuncture Treatment Research Studies
- Ovarian cancer diagnosis and treatment
- Hepatitis B Virus Studies
- Herpesvirus Infections and Treatments
- Stroke Rehabilitation and Recovery
- Plant Virus Research Studies
- Nonmelanoma Skin Cancer Studies
- Music Therapy and Health
- Telemedicine and Telehealth Implementation
- Renal cell carcinoma treatment
- Clinical practice guidelines implementation
- Meta-analysis and systematic reviews
- Cardiac, Anesthesia and Surgical Outcomes
- Delphi Technique in Research
- Neuroblastoma Research and Treatments
- Pancreatic and Hepatic Oncology Research
- Enhanced Recovery After Surgery
- Pain Management and Placebo Effect
- Ethics in Clinical Research
University of Freiburg
2019-2025
Witten/Herdecke University
2014-2025
University Hospital Ulm
2022-2025
University Medical Center Freiburg
2019-2023
Erasmus MC
2023
National Center for Complementary and Integrative Health
2020
The purpose of this study was to investigate the effect rhythmic embrocation (RE), a massage technique, on postoperative stress levels (measured by heart rate variability) in colorectal cancer surgery patients compared empathic conversation. included 68 who were randomized into three groups: one received RE from professionals, another students, and third conversations. Stress quantified using variability before after interventions. standard deviation heartbeat intervals (SDNN) increased more...
Cutaneous squamous cell carcinoma (CSCC) is a common locally invasive skin cancer which rarely metastasises. First-line treatment surgical excision, curative in most cases. Viscum album extract (VAE) widely used herbal with cytotoxic, apoptogenic and immunological effects, but has not been investigated CSCC.A 78-year-old patient histologically diagnosed CSCC refused excision was treated peri-lesional high-dose VAE. After 10 months of the had disappeared clinically. The recurrence-free for 4...
Malignant pleural mesothelioma (MPM) is a rare cancer with dismal prognosis. Viscum album extracts (VAE) have strong immune stimulatory properties, cytotoxic effects, can downregulate genes and inhibit angiogenesis. VAE are often used as an adjunct treatment in patients but rarely been investigated MPM. Helleborus niger (HNE) anticancer therapy since antiquity, also show tumor specific effects. We present case of 64-year old woman epithelioid MPM the right chest node involvement (T2N1M0,...
Abstract Background The coronavirus disease 2019 (COVID-19) pandemic is a threat to ongoing clinical trials necessitating regular face-to-face, in-person meetings, particularly in participants with high risk of complications. Guidance on how handle and safely continue such lacking. Chronically ill elderly individuals require—in addition protection from infection—regular physical exercise social contact remain healthy. Solutions these conflicting necessities are needed. ENTAIER-randomised...
Adenoid cystic carcinoma (ACC) is a rare type of cancer that typically originates in the salivary glands. Surgical removal can lead to functional loss and psychological distress. Viscum album extract (VAE) herbal remedy with dose-dependent cytotoxic, apoptogenic immunological effects. In some case reports, tumour regression has been observed following high-dose local applications VAE. An active 88-year-old man fast-growing ACC hard palate refused surgical received intratumoural injections...
Metastatic malignant cutaneous melanoma (MCM)-a highly immunogenic cancer-typically has a poor prognosis. Viscum album extracts (VAEs) have strong immune-stimulating, apoptogenic, and cytotoxic effects.A 66-year-old MCM patient with newly diagnosed lymph node metastases opted for sole VAE treatment. VAEs were initially applied subcutaneously, then later in exceptionally high, fever-inducing doses, both intravenously intralesionally. The shrunk over the following months, after 2 years, all...
Abstract Background Skull metastases are rare, they can eventually cause pain, and invade the brain. Viscum album extracts (VAEs) used as an adjuvant treatment in cancer. Methods Results A 68‐year‐old patient with rectal cancer presented lung metastases, to multiple bone sites, chest wall, liver were later identified. Histological examination of one lesions revealed additional thyroid carcinoma. An osteolytic parietal lesion progressed a painful metastasis skull despite radiotherapy...
Abstract Rationale: Carcinoma in situ (CIS) of the uterine cervix is a premalignant condition squamous epithelium. The standard treatments are excision and ablation procedures; for women with positive margins, hysterectomy recommended. Patient concerns: A 47-year-old Peruvian woman recurrent candidal vaginitis had been diagnosed colpocervicitis metaplasia 8 years ago, which were not treated. Diagnoses: patient was CIS after cervical conization procedure. She refused radical opted integrative...
Metastatic pancreatic cancer has a dismal prognosis. Many patients seek integrative care as an add-on to their conventional treatment. Viscum album extracts (VAE)-widely used adjunct treatment-have cytotoxic, apoptogenic, and immune stimulatory properties. A statistically significant survival benefit been demonstrated for VAE in advanced cancer.A 28-year old patient presented with painless jaundice was subsequently diagnosed adenocarcinoma liver metastases.He treated FOLFIRINOX/Mitomycin,...
A nodular lymphocyte predominant Hodgkin's lymphoma (NLPHL) is a lymphoproliferative neoplasm with fair prognosis, but the possibility of malignant transformation into diffuse large B-cell (DLBCL) high. DLBCL progresses aggressively. Introduction rituximab therapy had led to improved outcomes. The use Viscum album extracts (VAE) in cancer established, their application are rare.A 65-year-old patient was diagnosed stage IIa splenomegaly, transformed from NLPHL, after 30-year history...
Epithelial ovarian cancer (EOC) has a poor prognosis in advanced stages. High-dose chemotherapy (HDC) was pursued the 1990s but not found to improve survival of patients with EOC larger studies. Many use Viscum album extracts (VAE). Also called European mistletoe, can lead improved quality life and reduced side effects may have synergistic cytotoxic proliferation-inhibiting when used together chemotherapy.A high-grade serous epithelial carcinoma peritoneal, adrenal, hepatic metastases (FIGO...
Advanced pancreatic cancer (aPC) has a poor prognosis with limited survival benefit from current standard treatment. Viscum album extracts (VAE) are used by many patients, showing immune-stimulating effects, improved quality of life, and in patients aPC.A 59-year-old architect developed epigastric pain. A cystic lesion the pancreas 45-mm diameter was detected. In follow-up magnetic resonance imaging, about one year later, multiple lesions were seen corpus tail pancreas; CA-19-9 elevated to...
Abstract Rationale Thymic neuroendocrine tumor (TNET) is very rare and characterized by a tendency to invade adjacent structures, frequent metastasis, resistance therapy, poor prognosis. Viscum album extracts (VAE) have shown immunological, apoptogenic, cytotoxic properties. Patient concerns A 54-year-old Peruvian man was suffering from constant fatigue, cough, dyspnea, fever for couple of months. Diagnoses He diagnosed with TNET (12.8 cm × 10 7 cm) stage IIIa, G1. Due the size extensive...
Abstract Background In elderly poeple, multimorbidity and polypharmacy increase while sensory, motor cognitive functions decrease. Falls occur in 30% of people aged 65 years older at least once per year, with injuries 10–20%. Reducing falls enhancing physical, emotional capacities are essential for healthy aging despite chronic disease. Eurythmy therapy (EYT) Tai Chi train balance, mobility concentrative sensory capacities. Methods eight trial sites (academic or community hospitals), 550...
BACKGROUND: Well-written and transparent case reports (1) reveal early signals of potential benefits, harms, information on the use resources; (2) provide for clinical research practice guidelines, (3) inform medical education. High-quality are more likely when authors follow reporting guidelines. During 20112012, a group clinicians, researchers, journal editors developed recommendations accurate in that resulted CARE (CAse REport) Statement Checklist. They were presented at 2013...
Recent research suggests an impact of psychological distress on postoperative outcomes in orthopedic and neurosurgery. It is widely unknown whether patients’ mood might affect the outcome complication rate colorectal surgery. Over a period 22 months, monocentric, observational study among patients undergoing elective surgery without creation ostomy was conducted. Patients were asked to fill standardized multi-dimensional questionnaire (MDMQ) preoperatively as well third, sixth, ninth days...
Merkel cell carcinoma (MCC) is a rare, aggressive, neuroendocrine skin tumor with frequent local recurrence, lymph node involvement, distant metastasis, and high mortality rate. Viscum album extracts (VAE) are widely used adjunct in cancer treatment show cytotoxic immune-modulating effects.A 64-year-old woman was diagnosed MCC of the left forearm. In following course 21 years, she experienced 4 episodes relapse (axillary, submandibular, axillary, clavicular). All lesions were surgically...
<b><i>Introduction:</i></b> Metastatic renal cell carcinoma has a poor prognosis. Treatment approaches with immunotherapy show promising results in subpopulations. <i>Viscum album</i> extracts – used as an adjunct to cancer treatment have cytotoxic, apoptogenic, and immune-stimulating properties synergistic effects chemotherapy agents. <b><i>Case Report:</i></b> A 51-year-old man was diagnosed metastatic of clear histology which...
Background: Bilateral asynchronous renal cell carcinoma (RCC) is infrequent. Immunotherapy the first-line treatment for advanced RCC not controlled by locoregional therapy. Viscum album extracts (VAE) have been shown to improve quality of life as well immunological and antineoplastic properties in different types cancers. Case Report: A 67-year-old man was diagnosed with Fuhrman grade 3/4 RCC, stage pT1bN0M0 right kidney. During subsequent 6 years, he underwent a nephrectomy two...
Retroperitoneal sarcomas are rare. Dedifferentiated liposarcomas (DDLs) high-grade tumors with a high propensity for local recurrence and metastasis associated reduced survival. Radical resection remains the standard treatment of sarcomas. Meanwhile, Viscum album L. extract (VAE) is used in cancer patients owing to its cytostatic immunomodulating effects ability improve patients’ quality life. Case Presentation: A 68-year-old male patient underwent DDL (T2 N0 M0, FNCLCC grade 2, stage IIIA)...
: Preoperative emotional distress has been linked to adverse health outcomes, diminished quality of life, increased symptom burden after surgery, and poorer postoperative outcomes. Therefore, this study aimed assess the impact perioperative on long-term outcomes patients undergoing colorectal surgery.