A5011439618- Microbial infections and disease research
- Cytomegalovirus and herpesvirus research
- Aquaculture disease management and microbiota
- Survey Sampling and Estimation Techniques
- interferon and immune responses
- Animal Virus Infections Studies
- Wildlife Ecology and Conservation
- Immune Cell Function and Interaction
- Mycotoxins in Agriculture and Food
- Sphingolipid Metabolism and Signaling
- Avian ecology and behavior
- Bacterial Genetics and Biotechnology
- Herpesvirus Infections and Treatments
- Calcium signaling and nucleotide metabolism
- Escherichia coli research studies
- Animal Disease Management and Epidemiology
- Animal health and immunology
- Veterinary medicine and infectious diseases
- Agroforestry and silvopastoral systems
- Streptococcal Infections and Treatments
- Plant and soil sciences
- Social Issues and Sustainability
- Toxoplasma gondii Research Studies
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Turtle Biology and Conservation
Washington State University
2013-2018
The Ohio State University
2008-2014
Bombay Natural History Society
2007
The non-steroidal anti-inflammatory drug diclofenac is a major cause of the rapid declines in Indian subcontinent three species vultures endemic to South Asia. causes kidney failure and death vultures. Exposure probably arises through feeding on carcasses domesticated ungulates treated with drug. However, before study reported here, it had not been established from field surveys ungulate that sufficient proportion was contaminated observed declines. We surveyed concentrations samples liver...
Mannheimia haemolytica consistently causes severe bronchopneumonia and rapid death of bighorn sheep (Ovis canadensis) under experimental conditions. However, Bibersteinia trehalosi Pasteurella multocida have been isolated from pneumonic lung tissues more frequently than M. by culture-based methods. We hypothesized that assays sensitive culture would detect in accurately. Therefore, our first objective was to develop a PCR assay specific for use it determine if this organism present the lungs...
Sphingolipids are present in membranes of all eukaryotic cells. Bioactive sphingolipids also function as signaling molecules that regulate cellular processes such proliferation, migration, and apoptosis. Human cytomegalovirus (HCMV) exploits a variety pathways to promote its own replication. However, whether HCMV modulates lipid is an essentially unexplored area research virus-host cell interactions. In this study, we examined the accumulation bioactive enzymes responsible for biosynthesis...
ABSTRACT Human cytomegalovirus (HCMV) infections are prevalent in human populations and can cause serious diseases, especially those with compromised or immature immune systems. The HCMV genome of 230 kb is among the largest herpesvirus genomes. Although entire sequence laboratory-adapted AD169 strain has been available for 18 years, precise number viral genes still question. We undertook an analysis transcriptome as approach to enumerate analyze gene products HCMV. Transcripts HCMV-infected...
Introducción. Los sistemas silvopastoriles (SSP) juegan un papel destacado en la captura de carbono el suelo y mitigación gases efecto invernadero. Objetivo. Cuantificar los servicios ecosistémicos ofrecidos por cuatro SSP comparación con una pradera gramíneas, valle medio del río Sinú, Colombia. Materiales métodos. Se midieron flujos metano óxido nitroso mediante uso cámaras cerradas, durante periodo ocho semanas consecutivas (septiembre a noviembre, 2013). También se midió orgánico dos...
ABSTRACT In the absence of livestock contact, recurring lamb mortality in bighorn sheep (Ovis canadensis) populations previously exposed to pneumonia indicates likely presence carriers pneumonia-causing pathogens, and possibly inadequate maternally derived immunity. To investigate this problem we commingled naïve, pregnant ewes (n=3) with rams (n=2). Post-commingling, all lambs born them acquired pathogens (leukotoxin-producing Pasteurellaceae Mycoplasma ovipneumoniae), subsequent between...
ABSTRACT Mannheimia haemolytica causes pneumonia in domestic and wild ruminants. Leukotoxin (Lkt) is the most important virulence factor of bacterium. It encoded within four-gene lktCABD operon: lkt A encodes structural protoxin, lktC a trans -acylase that adds fatty acid chains to internal lysine residues which then secreted from cell by type 1 secretion system apparatus lktB lktD . has been reported LktC-mediated acylation necessary for biological effects toxin. However, an LktC mutant we...
Interferons (IFNs) activate the first lines of defense against viruses, and promote innate adaptive immune responses to viruses. We report that immediate early 1 (IE1) protein human cytomegalovirus (HCMV) disrupts signaling by IFNγ. The carboxyl-terminal region IE1 is required for this function. found no defect in initial events IFNγ or nuclear accumulation signal transducer activator transcription (STAT1) IE1-expressing cells. Moreover, we did not observe an association between disruption...
Mannheimia (Pasteurella) haemolytica causes bronchopneumonia in domestic and wild ruminants. Leukotoxin is the critical virulence factor of M. haemolytica. Since β-hemolysis caused by a large number leukotoxin-positive isolates, all β-hemolytic isolates are considered to be leukotoxic as well. However, conflicting reports exist literature hemolytic properties One group researchers reported their leukotoxin-deletion mutants while another non-hemolytic. The objective this study was determine...