- Radiation Dose and Imaging
- Advanced X-ray and CT Imaging
- Liver Disease Diagnosis and Treatment
- Diet and metabolism studies
- Digital Radiography and Breast Imaging
- Diet, Metabolism, and Disease
- Radiology practices and education
- Advanced MRI Techniques and Applications
- Adipose Tissue and Metabolism
- Radioactivity and Radon Measurements
- Child Nutrition and Water Access
- Liver Disease and Transplantation
- Birth, Development, and Health
- Cardiac Imaging and Diagnostics
- Advanced Neuroimaging Techniques and Applications
- Diabetes and associated disorders
- Cardiovascular Disease and Adiposity
- Effects of Radiation Exposure
- Pancreatic function and diabetes
- Parasitic Infections and Diagnostics
- Atomic and Subatomic Physics Research
- MRI in cancer diagnosis
- Ultrasound in Clinical Applications
- Hemostasis and retained surgical items
- Hemophilia Treatment and Research
Christian Medical College & Hospital
2016-2025
Chinese University of Hong Kong
2021-2024
Shantou University
2021-2024
Christian Medical College
2006-2023
Heinrich Heine University Düsseldorf
2013-2017
Deutsches Diabetes-Zentrum e.V.
2013-2017
German Center for Diabetes Research
2017
Vellore Christian Medical College Foundation
2008
Hepatic steatosis, defined as increased hepatocellular lipid content (HCL), associates with visceral obesity and glucose intolerance. As exact HCL quantification by 1H-magnetic resonance spectroscopy (1H-MRS) is not generally available, various clinical indices are increasingly used to predict steatosis.The purpose of this study was test the accuracy NAFLD liver fat score (NAFLD-LFS), hepatic steatosis index (HSI) fatty (FLI) against 1H-MRS their relationships insulin sensitivity...
Recent preclinical studies showed the potential of nicotinamide adenine dinucleotide (NAD+) precursors to increase oxidative phosphorylation and improve metabolic health, but human data are lacking. We hypothesize that nicotinic acid derivative acipimox, an NAD+ precursor, would directly affect mitochondrial function independent reductions in nonesterified fatty (NEFA) concentrations. In a multicenter randomized crossover trial, 21 patients with type 2 diabetes (age 57.7 ± 1.1 years, BMI...
OBJECTIVE Diabetes among individuals with low BMI (<19 kg/m2) has been recognized for >60 years as a prevalent entity in low- and middle-income countries (LMICs) was formally classified “malnutrition-related diabetes mellitus” by the World Health Organization (WHO) 1985. Since WHO withdrew this category 1999, our objective to define metabolic characteristics of these establish that is distinct form diabetes. RESEARCH DESIGN AND METHODS State-of-the-art studies were used...
Background Early childhood stunting affects around 150 million young children worldwide and leads to suboptimal human potential in later life. However, there is limited data on the effects of early catch-up growth brain morphometry. Methods We evaluated volumes at nine years age a community-based birth-cohort follow-up study Vellore, south India among four groups based anthropometric assessments two, five, namely ‘Never Stunted’ (NS), ‘Stunted two caught up by five years’ (S2N5), (S2N9),...
Low birth weight (LBW) is common in the Indian population and may represent an important predisposing factor for type 2 diabetes (T2D) metabolic syndrome. Intensive examinations ethnic LBW Asian Indians have been almost exclusively performed immigrants living outside India. Therefore, we aimed to study impact of being born with a rural non-migrant population.One hundred seventeen non-migrant, young healthy men were recruited from cohort part south The subjects comprised 61 56 normal (NBW)...
Purpose The aims of this study were (i) to establish a robust and fast method quantify hepatocellular phosphorus compounds in molar concentration on 3T clinical scanner, (ii) evaluate its reproducibility, (iii) test feasibility for use large cohort studies. Method Proton-decoupled 31P magnetic resonance spectroscopy liver acquired 85 healthy subjects employing image selected in-vivo localization 13 min acquisition at 3T. Absolute quantification was achieved using an external reference...
Radiation-protective aprons are commonly used by interventionists to protect against the harmful effects of ionizing radiation. Choice appropriate with respect lead equivalence and weight is necessary for effective protection reduced physical strain. This study evaluates knowledge practice using radiation-protective interventionists.Ninety-one interventional radiologists who attended an annual conference were provided a questionnaire which included age, years experience, area expertise, type...
Protective lead or lead-equivalent (Pbeq) aprons play a key role in providing necessary shielding from secondary radiation to occupational workers. Knowledge on the integrity of these apparels during purchase is maintain adequate safety.The aim study was evaluate equivalence based simple quality assessment tool.0.25 mm and 0.5 lead-free 6 manufacturers were assessed using calibrated digital X-ray unit. The percentage attenuation values determined at 100 kVp an ionization chamber pixel...
Coronary angiography (CA) procedure uses various angiographic projections to elicit detailed information of the coronary arteries with some steep involving high radiation dose patients. This study intends evaluate doses and estimated risk from during CA performed using novel flat detector (FD) system improved image processing noise reduction techniques. Real-time monitoring kerma-area product (KAP) meter was for 140 patients Philips Clarity FD system. The involved seven standard projections,...
The transjugular intrahepatic portosystemic shunt (TIPS) procedure for decompression of the portal venous system generally performed under fluoroscopic guidance has undergone continuous technical modifications recently. Due to length procedure, fluoroscopy times are reasonably high, thus increasing risk from ionizing radiation. Radiation doses were measured 19 patients using dose area product (DAP) meter. average DAP value TIPS was 63.86 Gy cm(2) (21.12-117.07). can be reduced with use USG...
A micturating cystourethrography (MCU) examination is a specific radiological procedure that performed under fluoroscopic screening to visualize the bladder by filling it with contrast material and evaluate urethral morphology during voiding. It necessary radiation dose MCU since involves radiosensitive organs such as gonads. Radiation imparted 109 patients undergoing were measured using dose-area product (DAP) meter. Patients categorized into two groups based on whether of medium was done...
This study was carried out to determine the prevalence and identify species of intestinal parasitic infections among zoological garden workers inmates (animals birds), in University Ibadan Zoological Garden. Faecal samples were collected from all animals, birds zoo-keepers garden, 5 days after 2 before another periodic routine deworming session animals. The faecal examined, using normal saline, iodine, brineconcentration techniques, detect presence parasites. larvae or ova. zoo-workers given...
Radiation safety in computed tomography (CT) scanners is of concern due its widespread use the field radiological imaging. This study intends to evaluate radiation doses imparted patients undergoing thorax, abdomen and pelvic CT examinations formulate regional diagnostic reference levels (DRL) Tamil Nadu, South India. In-site dose measurement was performed 127 Nadu for a period 2 years as part Atomic Energy Regulatory Board (AERB)-funded project. Out scanners,13 were conventional; 53...
This study was intended to evaluate radiation risk patients during cerebral interventions and the contribution this from work practices. Thirty nine undergoing in a digital subtraction angiography suite were included study. Patients who underwent categorised into two groups according number of performed on them, their effective doses calculated. The dose for single intervention (group A) varied 1.55 15.9 mSv multiple B) 16.52 43.52 mSv. Two had alopecia irradiated scalp.
Fluoroscopy-guided interventions can potentially increase radiation risk to patients, if awareness on angiographic imaging technique and dose is neglected.To develop patient reference card from standardized techniques for various radiology performed using flat detector based angiography system.Real-time monitoring of exposure parameters were 16 types radiological interventions. Effective (ED) was estimated area product (DAP) PCXMC Monte Carlo simulation software. Radiation levels Biological...
Abstract Objective: To evaluate the radiation dose and image quality using a manual protocol modulation techniques in 6-slice CT scanner. Materials Methods: Two hundred twenty-one patients who underwent contrast-enhanced of chest were included study. For settings, constant tube potential (kV) current-time product (mAs) 140 kV 120 mAs, respectively, used. The angular z-axis utilized kV; mAs values automatically selected by machine. Effective doses calculated dose-length (DLP) was assessed...
Abstract Objectives Early detection of bleeding into a joint is crucial in patients with haemophilia. This study was designed to evaluate the sensitivity ultrasonography (USG) and magnetic resonance imaging (MRI) detect presence blood small concentrations simulated model mimic bleeding. Materials Methods Different plasma, varying from 0.1% 45%, were collected 10‐ml plastic syringes imaged using 12 18 MHz USG transducers 1.5T 3T MRI scanners, at different intervals time following dilution....
Abstract Aims To assess young healthy men from rural India, who had normal or low birth weights, using magnetic resonance spectroscopy to determine the potential differences in ectopic fat storage between weight groups, and if was associated with insulin resistance this population. Methods A total of 54 lean 49 (age range 18–22 years) India were recruited. All underwent anthropometry, spectroscopy, a hyperinsulinaemic‐euglycaemic clamp dual‐energy X‐ray absorptiometry. Results The median...
This study intends to evaluate the current level of computed tomography (CT) scanner doses installed in a region India. In-site CT dose measurement was performed for 127 scanners index (CTDI) measured using 10 cm3 pencil ion chamber and 32-cm polymethyl methacrylate body phantom. The numbers image noise were phantom software available on each scanner. Of scanners, 13 conventional, 53 helical single-section, 44 multidetector row (MDCT) 17 refurbished machines. mean-weighted CTDI (CTDIw)...