A5078896743- Child Nutrition and Water Access
- Infant Development and Preterm Care
- Birth, Development, and Health
- Child Nutrition and Feeding Issues
- Obesity, Physical Activity, Diet
- Early Childhood Education and Development
- Cerebral Palsy and Movement Disorders
- Poverty, Education, and Child Welfare
- Neonatal Respiratory Health Research
- Neonatal and fetal brain pathology
- Food Security and Health in Diverse Populations
- Muscle Physiology and Disorders
- Family and Disability Support Research
- Child and Adolescent Psychosocial and Emotional Development
- Infant Nutrition and Health
- Neurogenetic and Muscular Disorders Research
- Global Maternal and Child Health
- Viral gastroenteritis research and epidemiology
- Infant Health and Development
- Nutritional Studies and Diet
- Assisted Reproductive Technology and Twin Pregnancy
- Sleep and related disorders
- Child Development and Digital Technology
- Migration, Health and Trauma
- Breastfeeding Practices and Influences
University of Virginia Children's Hospital
2016-2025
University of Virginia
2015-2024
NeuroDevelopment Center
2023-2024
Boston Medical Center
2024
University of Virginia Health System
2023
University of Virginia Medical Center
2023
Center for Global Health
2012-2020
Icahn School of Medicine at Mount Sinai
2017
Foundation for the National Institutes of Health
2016
Pennsylvania State University
2016
Critical to the design and assessment of interventions for enteropathy its developmental consequences in children living impoverished conditions are non-invasive biomarkers that can detect intestinal damage predict effects on growth development. We therefore assessed fecal, urinary systemic predictors 375 6-26 month-old with varying degrees malnutrition (stunting or wasting) Northeast Brazil. 301 these returned followup anthropometry after 2-6m. Biomarkers correlated stunting included plasma...
Although sugar-sweetened beverage (SSB) consumption has been tightly linked to weight status among older children, the data regarding these relationships in children aged 2 5 years have mixed. Our objective was evaluate longitudinal and cross-sectional between SSB years.
Deficits in weight gain and linear growth are seen frequently among children areas where malnutrition recurrent infections common. Although both inflammation can result hormone (GH) resistance, the interrelationships of infection, inflammation, deficits developing remain unclear. The aim this study was to evaluate relationships between low levels systemic factors, anthropometry a case-control cohort underweight normal northern Brazil.We evaluated data from 147 ages 6 24 mo MAL-ED...
• On the basis of observational studies (level C), preterm birth is a leading cause neurodevelopmental disabilities in children, and degree disability inversely correlated with gestational age at birth. When comparing performance children to developmental norms, “corrected age” or from due date rather than should be used for first 24 36 months. clinicians pay specific attention sensory function born because incidence visual hearing impairments higher term children. Due elevated risk...
Summary Background Obesity in childhood is related to multiple lifestyle factors. Our objective was evaluate the relationship between consumption of 100% fruit juice and weight status over time among pre‐school children. Methods We used linear logistic multivariable regression body mass index ( BMI ) z ‐score overweight/obese as a function intake for 8950 children examined at ages 2, 4 5 years part Early Childhood Longitudinal Study–Birth Cohort, representative sample U nited S tates....
Short night-time sleep duration is a possible factor contributing to childhood obesity. Our objective was evaluate associations between timing (including bedtime and waketime) weight gain in 4- 5-year-old children.
An estimated one-third of children younger than 5 years in low- and middle-income countries fail to meet their full developmental potential. The first year life is a period critical brain development also when most the morbidity from infection suffered. We aimed determine if clinical biological markers inflammation predict cognitive, language, motor outcomes living an urban slum Bangladesh. Children Dhaka, Bangladesh were observed birth until 24 months age. Febrile illness was used as marker...
More epidemiological data are needed on risk and protective factors for child development. In The Etiology, Risk Factors Interactions of Enteric Infections Malnutrition the Consequences Child Health Development (MAL-ED) cohort study, we assessed development in a harmonious manner across 8 sites Bangladesh, Brazil, India, Nepal, Pakistan, Peru, South Africa, Tanzania. From birth to 24 months, language acquisition were via Bayley Scales Infant Toddler modified MacArthur Communicative...
Summary Background Relationships between birthweight and future obesity risk remain unclear. Objective To assess associations later in a nationally representative cohort of early school‐aged children. Methods We used linear logistic regression to evaluate 10 186 term‐ or preterm children the Early Childhood Longitudinal Study‐Kindergarten Cohort 2011 for relationships change BMI z‐score from kindergarten‐to‐second grade. All analyses were adjusted sex, race/ethnicity, parental education...
To examine the relationships between growth (birth to age 2 years) and developmental outcomes in children born with very low birthweight (VLBW).Motor mental development VLBW were regressed on anthropometric measurements at birth, 9 months years using multivariable regression.The Early Childhood Longitudinal Study-Birth Cohort, a longitudinal cohort, community sample, designed be representative of across USA.950 (<1500 g).Motor cognitive scores Bayley Scales 24 chronological age.A high...
Background Millions of children worldwide especially in the Asian subcontinent are vulnerable to early childhood stunting. There contradictory reports association between catch-up growth and school age cognition. Methods A community-based birth cohort recruited 2010 2012 from urban slums Vellore, India was followed up until 9 years age. From regular anthropometric measurements, stunting status for each individual child calculated at 2, 5 years. Cognition assessed using Malin’s Intelligence...
<h3>Objective</h3> To evaluate relationships between type of milk consumed and weight status among preschool children. <h3>Design</h3> Longitudinal cohort study. <h3>Setting</h3> The Early Childhood Study, Birth Cohort, a representative sample US <h3>Participants</h3> 10 700 children examined at age 2 4 years. <h3>Main outcome measures</h3> Body mass index (BMI) z score overweight/obese as function intake. <h3>Results</h3> majority drank whole or 2% (87% years, 79.3% years). Across...
Objective: To examine how many hours preschool children in the United States sleep at night and to test hypothesis that with shorter nighttime duration are more likely exhibit externalizing behaviors. Methods: The Early Childhood Longitudinal Study-Birth Cohort is a nationally representative longitudinal cohort study followed born 2001 through kindergarten. This cross-sectional examines wave (n = ∼8950). We estimated from parent's reports of their 4-year-old child's typical weekday bed wake...
The home environment provides the context for much of a child's early development. Examples important aspects include safety, cleanliness, and opportunities cognitive stimulation. This study sought to examine psychometric properties an adapted form Home Observation Measurement Environment (HOME; Caldwell & Bradley, 1984, 2003) across eight international sites MAL-ED project (Dhaka, Bangladesh; Vellore, India; Bhakatapur, Nepal; Naushahro Feroze, Pakistan; Fortaleza, Brazil; Loreto, Peru;...
Objectives To evaluate links between the volume of milk consumed and weight height status in children aged 4 5 years. Design We analysed data from 8950 followed up as part Early Childhood Longitudinal Survey, Birth cohort, a nationally representative cohort children. used linear logistic regression to assess associations daily servings intake at age years with z-scores body mass index (BMI), weight-for-height years, adjusted for sex, race/ethnicity, socioeconomic type consumed. Results Among...
Abstract Although many studies around the world hope to measure or improve developmental progress in children promote community flourishing and productivity, growth is sometimes used as a surrogate because cognitive skills are more difficult measure. Our objective was assess how childhood measures of anthropometry correlate with child development low‐income settings high prevalence poor nutrition enteric disease, inform considering outcomes absence direct skill assessment. Children from...
Clinical assessments for neuromuscular disorders, such as Spinal Muscular Atrophy (SMA) and Duchenne Dystrophy (DMD), continue to rely on subjective measures monitor treatment response disease progression. We introduce a novel method using wearable sensors objectively assess motor function during daily activities in 19 patients with DMD, 9 SMA, 13 age-matched controls. Pediatric movement data is complex due confounding factors limb length variations growing children variability speed. Our...
Background Early childhood stunting affects around 150 million young children worldwide and leads to suboptimal human potential in later life. However, there is limited data on the effects of early catch-up growth brain morphometry. Methods We evaluated volumes at nine years age a community-based birth-cohort follow-up study Vellore, south India among four groups based anthropometric assessments two, five, namely ‘Never Stunted’ (NS), ‘Stunted two caught up by five years’ (S2N5), (S2N9),...
Zulfi Bhutta and colleagues lay out research priorities for global child diarrheal disease over the next 15 years, which they developed using Child Health Nutrition Research Initiative (CHNRI) method. Please see later in article Editors' Summary
The Etiology, Risk Factors and Interactions of Enteric Infections Malnutrition the Consequences for Child Health Development (MAL-ED) cohort in study's Fortaleza, Brazil, catchment area has a population approximately 82 300 inhabitants. Most households (87%) have access to clean water, 98% electricity, 69% improved toilet/sanitation. childbirths occur at hospital, under-5 mortality rate is 20 per 1000 live births. MAL-ED case-control study population, identified through Institute Promotion...
To evaluate the relationship between prolonged neonatal intensive care unit (NICU) stay after birth and childhood neurodevelopmental measures from age 9 months to kindergarten.Longitudinal cohort study.This study examined a nationally representative sample of 10 700 participants Early Childhood Longitudinal Sample-Birth Cohort selected those who had NICU (n=2100). These children were followed kindergarten.Days in NICU.Childhood early academic scores.Increasing length significant negative...