- Legume Nitrogen Fixing Symbiosis
- Mosquito-borne diseases and control
- Plant Pathogenic Bacteria Studies
- Genomics and Phylogenetic Studies
- Nematode management and characterization studies
- Selenium in Biological Systems
- Dengue and Mosquito Control Research
- Viral Infections and Vectors
- Malaria Research and Control
- Infections and bacterial resistance
- Air Quality and Health Impacts
- Cerebral Palsy and Movement Disorders
- Mycobacterium research and diagnosis
- Virology and Viral Diseases
- Blood disorders and treatments
- Bacterial Identification and Susceptibility Testing
- Sulfur Compounds in Biology
- Geotechnical Engineering and Soil Stabilization
- Bayesian Methods and Mixture Models
- Microbial infections and disease research
- Gallbladder and Bile Duct Disorders
- Technology and Data Analysis
- Natural Antidiabetic Agents Studies
- Children's Physical and Motor Development
- Coastal wetland ecosystem dynamics
Oregon State University
2024-2025
University of California, Riverside
2019-2023
The University of Texas at Austin
2023
Noakhali Science and Technology University
2016-2023
Bangladesh University of Engineering and Technology
2023
BRAC University
2023
Imperial College London
2020
University of Dhaka
2016
Root nodulating rhizobia are nearly ubiquitous in soils and provide the critical service of nitrogen fixation to thousands legume species, including staple crops. However, magnitude fixed provided hosts varies markedly among strains, despite host legumes having mechanisms selectively reward beneficial strains punish ones that do not fix sufficient nitrogen. Variation services microbial mutualists is considered paradoxical given select genotypes. Moreover, recurrent evolution non-fixing...
ABSTRACT Comprehensive and accurate genome annotation is crucial for inferring the predicted functions of an organism. Numerous tools exist to annotate genes, gene clusters, mobile genetic elements, other diverse features. However, these pipelines can be difficult install run, specialized a particular element or feature, lack annotations larger elements that provide important genomic context. Integrating results across analyses also understanding function. To address challenges, we present...
Clinical assessments for neuromuscular disorders, such as Spinal Muscular Atrophy (SMA) and Duchenne Dystrophy (DMD), continue to rely on subjective measures monitor treatment response disease progression. We introduce a novel method using wearable sensors objectively assess motor function during daily activities in 19 patients with DMD, 9 SMA, 13 age-matched controls. Pediatric movement data is complex due confounding factors limb length variations growing children variability speed. Our...
Whole genome sequencing provides the highest resolution for characterizing pathogen evolution, epidemiology, and diagnostics. Genome assemblies contain information on identity potential phenotypes of a pathogen. Likewise, variant calling can inform transmission patterns evolutionary relationships. Recent improvements in Oxford Nanopore long-read have made its use attractive genomic epidemiology. However, accuracy optimal strategy analysis reads remains to be determined. We compared Illumina...
Multipartite bacterial genome organization can confer advantages including coordinated gene regulation and faster replication but is challenging to maintain. Agrobacterium tumefaciens lineages often contain a circular chromosome (Ch1), linear (Ch2), multiple plasmids. We previously observed that in some stocks of the lab model strain C58, Ch1 Ch2 were fused into dicentric chromosome. Here we analyzed natural isolates from French Collection for Plant-Associated Bacteria (CFBP) identified two...
Abstract Background The next-generation sequencing (NGS) technology facilitates in-depth study of host-pathogen metatranscriptome. We, therefore, implicated phylodynamic and transcriptomic approaches through NGS to know/understand the dengue virus (DENV) origin host response with fever. Methods In this study, blood serum RNA was extracted from 21 patients 3 healthy individuals. Total data were analyzed for phylogenetic, phylodynamic, differential express gene (DEG), ontology (GO) using...
Dimethyl selenide (DMSe) is one of the major volatile organoselenium compounds released from aquatic and terrestrial environments through microbial transformation plant metabolism. The detailed processes DMSe leading to secondary organic aerosol (SOA) formation pulmonary health effects induced by inhalation DMSe-derived SOA remain largely unknown. In this study, we characterized chemical composition yields produced oxidation with OH radicals O3 in controlled chamber experiments. Further,...
Abstract Comprehensive and accurate genome annotation is crucial for inferring the predicted functions of an organism. Numerous tools exist to annotate genes, gene clusters, mobile genetic elements, other diverse features. However, these pipelines can be difficult install run, specialized a particular element or feature, lack annotations larger elements that provide important genomic context. Integrating results across analyses also understanding function. To address challenges, we present...
?-Defensin is a group of polypeptides with antimicrobial activity found in the host defense system and it widely distributed in, but not limited to mammalian epithelial cells phagocytes. These molecules protect organism from diverse spectrum bacteria, viruses, fungi, protozoan parasites. Different studies have revealed widesequence variation within ?-defensin sequences, underlying evolutionary cause well-studied. In this study, gene 25 vertebrate species has been comprehensively collected...
The impact of the COVID-19 outbreak had devastating consequences globally with 20,675,770 affected and 749,061 dead. Despite different measures to restrict transmission, death toll continues rise. SAARC group countries comprising eight nations—Afghanistan, Bangladesh, Bhutan, India, Maldives, Nepal, Pakistan Sri Lanka, where 23.75% world population reside, implemented containment at stages varying consequences. In this review, we examined onset transmission virus in each country an early...
Garbage collection is a fundamental aspect of Java Virtual Machine (JVM) memory management, and choosing the optimal garbage collector essential for attaining application performance. In this work, we conduct experiments with big data benchmarks from DaCapo Renaissance benchmark suites in both fixed variable heap environments to determine efficacy JDK 20's collectors. The ZGC algorithm has highest throughput shortest pause periods, whereas Serial GC lowest longest intervals. Additionally, it...
Abstract Objectives The lack of a dengue disease animal model and the complex immune interaction in infection hinders study host response immunopathogenesis. development next-generation sequencing (NGS) technology allowed researchers to transcriptomic profiles human in-depth. We, therefore, implicated phylodynamic approaches through NGS know origin virus (DENV) their infected patients with fever. Methods To determine whole genome sequences profiles, RNA was extracted from serum samples 3...
Background: In the last 20 years, management of ureteric stones has changed dramatically from an open operative procedure to endoscopic,minimally invasive and non methods. Urinary stone disease is a major problem due its high prevalence incidence recurrence. The present study aimed determine outcome in situ Extracorporeal Shock-Wave Lithotripsy (ESWL) mid-ureteric terms clearance, per post complications. Methods: This prospective was conducted Department Urology, Bangabandhu Sheikh Mujib...
Zika is a mosquito borne virus from Flaviviridae family, which recently caused pandemic fever that can lead to development of encephalitis. Even so, this relatively new - it was first discovered in 1947. Recent an interest on its sudden emergence as fatal human pathogen because previously, known the viral rhesus monkey. Why and how crossed species barrier, spread throughout world, gained ability create epidemic these questions remained unsolved. In study, selection pressure two protein...
Estimating phylogenetic trees from molecular data often involves first performing a multiple sequence alignment of the sequences and then identifying tree that maximizes likelihood computed under model nucleotide substitution. However, is computationally challenging for long sequences, especially in presence genomic rearrangements. To address this, methods constructing without aligning i.e. alignment-free have been proposed. They are generally fast can be used to construct large number...