- Orthopaedic implants and arthroplasty
- Hemophilia Treatment and Research
- Blood Coagulation and Thrombosis Mechanisms
- Orthopedic Infections and Treatments
- Total Knee Arthroplasty Outcomes
- Hip disorders and treatments
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Hip and Femur Fractures
- Knee injuries and reconstruction techniques
- Shoulder and Clavicle Injuries
- Bone fractures and treatments
- Hemostasis and retained surgical items
- Shoulder Injury and Treatment
- Global Health Workforce Issues
- Anesthesia and Pain Management
- Primary Care and Health Outcomes
- Trauma Management and Diagnosis
- Chronic Myeloid Leukemia Treatments
- Vascular Procedures and Complications
- Sports injuries and prevention
- Spine and Intervertebral Disc Pathology
- Infectious Diseases and Tuberculosis
- Cerebral Palsy and Movement Disorders
- Lower Extremity Biomechanics and Pathologies
- Platelet Disorders and Treatments
Christian Medical College
2007-2024
Christian Medical College & Hospital
2015-2024
Alice Springs Hospital
2022-2024
Flinders University
2024
University Medical Center Utrecht
2004
This new edition of the World Federation Hemophilia (WFH) guidelines for management hemophilia comes at an exciting time in evolution diagnosis and treatment this condition. Since publication second 2012, tremendous advances have been made several aspects hemophilia. These include genetic assessment as well therapy with many innovative therapeutic products including extended half-life factor VIII (FVIII) IX (FIX) products, a bi-specific antibody, hemostasis rebalancing drugs now clinical...
OBJECTIVE. The purpose of this article is to assess the reliability interpretation ultrasound findings according data blinding in maturing hemophilic joints and determine diagnostic accuracy compared with MRI for assessing joint components. SUBJECTS AND METHODS. Ankles (n = 34) or knees 25) boys hemophilia von Willebrand disease (median age, 13 years; range, 5-17 years) were imaged by ultrasound, MRI, radiography two centers (Toronto, Canada, Vellore, India). Ultrasound scans performed...
Loss of proprioception following an anterior cruciate ligament (ACL) injury has been well documented. We evaluated in both the injured and uninjured limb 25 patients with ACL healthy controls, as assessed by joint position sense (JPS), threshold for detection passive movement (TDPM) postural sway during single-limb stance on a force plate. There were significant proprioceptive deficits ACL-deficient knees compared control knees, angle reproduction test (on JPS) single stance. The degree loss...
This study was undertaken to determine the correlation between radiological changes in haemophilic arthropathy [X-ray, Ultrasound (US) and MRI] clinical assessment as determined by Hemophilia Joint Health Score (HJHS); document US MRI joints that appear normal on plain X-ray evaluation.Of 55 (22 knees 33 ankles) 51 patients with haemophilia/von Willebrand disease, a median age of 15 years (range: 5-17) were assessed using X-rays (Pettersson score) examination (HJHS) at two centres (Toronto,...
Summary. Joint morbidity in haemophilia has traditionally been measured using clinical and radiological scores. There have no reliable, validated tools for the assessment of functional independence persons with till recently. The Functional Independence Score Haemophilia (FISH) developed as a performance based tool to address this need. FISH is designed measure patient’s performing activities daily living (grooming eating, bathing dressing), transfers (chair floor), mobility (walking, step...
Summary The study was undertaken to document cartilage and soft tissue changes/findings in ankles knees of normal children different age groups be used for comparison the assessment with haemophilia. Cartilage thickness changes were recorded at predetermined sites ankles/knees on both US MRI healthy boys three groups: 7–9; 10–14; 15–18 years. To assess validity ultrasound measurements, an ex vivo done using agar phantoms techniques scanners similar those applied . Twenty (48%) 22 (52%) 42...
For persons with hemophilia, optimization of joint outcomes is an important unmet need. The aim this initiative was to determine use ultrasound in evaluating arthropathy and move toward consensus among hemophilia care providers regarding the preferred protocols for global adaptation.A survey treatment centers conducted that focused on understanding how why being used endeavored definitions both point-of-care musculoskeletal (POC-MSKUS) full diagnostic ultrasound, terminology describe...
Three patients referred for MRI of the foot were found to have imaging features characteristic mycetoma. Two presented with recurrent soft tissue masses, which operated on several times and not suspected be infective aetiology. The third patient had typical clinical a history blackish granule discharge. In all three patients, showed conglomerate areas small round discrete T(2) weighted hyperintense lesions, representing granulation surrounded by low-signal-intensity rim intervening fibrous...
Abstract Introduction The Hemophilia Joint Health Score (HJHS) was developed to detect early changes in joint health children and adolescents with haemophilia. HJHS is considered by some be too time consuming for clinical use this may limit broad adoption. Aim This study a first step develop shorter and/or more convenient version of the measurement function young adults haemophilia, combining real‐life data expert opinion. Methods A cross‐sectional multicenter secondary analysis on pooled...
Patients and methods A longitudinal study was carried out in 255 children from 10 centres nine developing countries over 5 years to assess the musculoskeletal outcome of on episodic factor replacement. Outcome documented by assessment annual joint bleeding rate ( AJBR ), WFH clinical Pettersson radiological scores as well FISH score for activities. Of 203 patients whom data available at end years, 164 who had received only treatment are included this report. Results The median age beginning...
The aim of this study is to characterise the clinical and microbiological profile adult patients treated at our orthopaedic unit with septic arthritic between 2006 2017.A total 70 who were admitted a diagnosis arthritis 2017 included in study. patients' epidemiological characteristics surveyed; complications relating treatment identified.Septic was more common among males (83%). About 75% presented history fever. knee most commonly affected joint (71%), followed by hip. While C-reactive...
Australian Indigenous (AI) populations face significant socioeconomic disadvantage and have poorer health outcomes when compared to their non-AI counterparts. There is a paucity of published literature on following hip fracture in the AI population.
Summary. Severe haemophilia (factor [F]VIII/FIX activity < 0.01 IU mL −1 ) is characterized by repeated haemarthroses resulting in severe arthropathy adulthood. In 1958, Professor Nilsson Sweden introduced prophylactic infusions with clotting factor concentrates at regular intervals order to maintain levels above and prevent bleeding. Since then, evidence of the long‐term beneficial effects treatment for has been increasing it become recommended strategy children both World Health...
Bipolar fracture dislocations of the clavicle are rare injuries, usually result high-energy direct trauma. Since original description by Porral in 1831, only a handful individual case reports and series Beckman Sanders have been reported literature. Management these injuries has remained controversial ranging from nonoperative to aggressive surgery. We report on young army cadet who had lateral end clavicle, with an anterior dislocation sternoclavicular joint. Despite being planned for...
Assessment of musculoskeletal function in individuals with haemophilia has been attempted clinimetric instruments, which use predetermined domains for assessing the same. This study introduces application an instrument, Canadian Occupational Performance Measure (COPM), is open-ended questionnaire that allows patients to prioritize their needs and rate performance different tasks daily living as well satisfaction performing them. To utility COPM evaluating functional status assess its...