A5055925852- Glutathione Transferases and Polymorphisms
- Genomics, phytochemicals, and oxidative stress
- vaccines and immunoinformatics approaches
- Liver Disease Diagnosis and Treatment
- Gout, Hyperuricemia, Uric Acid
- Alcohol Consumption and Health Effects
- Inflammasome and immune disorders
- Plant Pathogens and Resistance
- Monoclonal and Polyclonal Antibodies Research
- Immunotherapy and Immune Responses
- Herpesvirus Infections and Treatments
- Animal Disease Management and Epidemiology
- Diet, Metabolism, and Disease
- Machine Learning in Bioinformatics
- Liver Disease and Transplantation
- Aluminum toxicity and tolerance in plants and animals
- Pancreatitis Pathology and Treatment
- Soybean genetics and cultivation
- Biochemical and Structural Characterization
- Cardiovascular Disease and Adiposity
- Plant Micronutrient Interactions and Effects
- Nitrogen and Sulfur Effects on Brassica
- Venomous Animal Envenomation and Studies
- Obesity, Physical Activity, Diet
- Blood Pressure and Hypertension Studies
Shahjalal University of Science and Technology
2017-2022
University of Alberta
2020-2022
Background and objectives Recent studies have shown that hyperuricemia is commonly associated with dyslipidemia, cardiovascular diseases, hypertension metabolic syndrome. Elevated serum uric acid has been demonstrated to be obesity in the adult population many countries; however, there still a lack of evidence for Bangladeshi population. The aims this study were evaluate prevalence determine relationship between (SUA) among adults. Methods In cross-sectional study, blood samples collected...
Although the link between elevated uric acid and metabolic syndrome has been reported in some studies; relationship of serum (SUA) with lipid profile not well studied or little is known so far. This study was conducted to assess SUA among general adults Bangladesh.In total, 280 blood samples were collected from adult participants (male, n = 150 female, 130) analyzed for (TC, TG, HDL LDL) levels. The subjects divided by quartiles based on levels (Q1: ≤225 μmol/L, Q2: 226-285 Q3: 286-340...
Glutathione S-transferase (GST) refers to one of the major detoxifying enzymes that plays an important role in different abiotic and biotic stress modulation pathways plant. The present study aimed a comprehensive genome-wide functional characterization GST genes proteins tomato (Solanum lycopersicum L.). whole genome sequence analysis revealed presence 90 tomato, largest gene family reported till date. Eight segmental duplicated pairs might contribute significantly expansion SlGST family....
In epidemiological studies, serum uric acid (SUA) has been shown to be associated with hypertension and cardiovascular disorders. However, limited studies have evaluated the relationship between SUA glucose levels in healthy diabetic individuals their observed findings are inconsistent. This study aimed examine fasting blood (FBG) among healthy, prediabetic Bangladesh. total, 310 samples were collected from 215 male 95 female subjects analyzed for FBG, SUA, lipid levels. All participants...
Abstract Glutathione S-transferases (GSTs) compose a family of multifunctional enzymes involved in the numerous aspects regulating plant growth, development, and stress response. An silico genome-wide analysis pepper ( Capsicum annuum L.) was performed to identify eighty-five GST genes that were annotated according their chromosomal location. Segmental duplication contributed more than tandem for expansion gene pepper. All identified members belong ten different classes which are highly...
Experimental evidence suggests a causal role of serum uric acid (SUA) in hypertension development. Currently, there are few data available on the association between SUA and hypertension; from Bangladeshi adults not yet. This study evaluated with among adults. Blood samples were obtained 140 males 115 females analyzed for lipid levels. Hypertension was defined as SBP ≥ mmHg and/or DBP 90 mmHg. All participants divided into four quartiles based concentrations. Association by logistic...
Abstract Background Type 2 diabetes (T2D) is a major public health concern affecting millions of people worldwide. The relationship between liver enzymes and T2D has been reported in limited studies; however, there still lack evidence for the Bangladeshi population. This study aimed to evaluate prevalence elevated examine its association with adults. Methods A total 270 individuals (110 diabetic 160 nondiabetic) were enrolled study. Alanine aspartate aminotransferase (ALT, AST), alkaline...
Abstract Background Hypertension is a major contributing factor to cardiovascular disease and leading cause of death in the world. The association between hepatic enzymes hypertension has been reported limited studies findings are inconsistent; data from Bangladeshi adults not available yet. This study was conducted estimate prevalence elevated liver evaluate with adults. Methods In this cross-sectional study, 302 blood samples were collected adult participants analyzed serum concentrations...
Herpes simplex virus type 1 (HSV-1) and 2 (HSV-2) cause a variety of infections including oral-facial infections, genital herpes, herpes keratitis, cutaneous infection so on. To date, FDA-approved licensed HSV vaccine is not available yet. Hence, the study was conducted to identify characterize an effective epitope based polyvalent against both types Simplex Virus. The selected proteins were retrieved from ViralZone assessed design highly antigenic epitopes by binding analyses peptides with...
Glutathione transferases (GSTs) constitute an ancient, ubiquitous, multi-functional antioxidant enzyme superfamily that has great importance on cellular detoxification against abiotic and biotic stresses as well plant development growth. The present study aimed to a comprehensive genome-wide identification functional characterization of GST family in one the economically important legume plants— Medicago truncatula . Here, we have identified total ninety-two putative MtGST genes code for 120...
Hypertension is a major cause of cardiovascular disease and related mortality worldwide. The presence general abdominal obesity in hypertensive individuals increases the risk mortality. However, evidence on burden hypertension associated factors are lacking or limited among young adult students Bangladesh. This study measured prevalence with university In this study, total 1011 (647 males 364 females) were enrolled nine public universities eight divisional regions Data collected...
Snake venom is a mixture of many biological components. Snakes usually use their venomic armory to tackle different prey and predators in adverse natural world. Among various components the snake venom, neurotoxins play an important role exerting effect by blocking neuromuscular transmission through selective binding muscle nicotinic Acetyl-Choline Receptors (nAChR). A set 30 reference protein sequences representing neurotoxin were retrieved from NCBI database characterized for...
ABSTRACT Herpes simplex virus type 1 (HSV-1) and 2 (HSV-2) cause a variety of infections including oral-facial infections, genital herpes, herpes keratitis, cutaneous infection so on. To date, FDA-approved licensed HSV vaccine is not available yet. Hence, the study was conducted to identify characterize an effective epitope based polyvalent against both types Simplex Virus through targeting six viral proteins. The selected proteins were retrieved from viralzone assessed design highly...