A5041077751- vaccines and immunoinformatics approaches
- SARS-CoV-2 and COVID-19 Research
- Computational Drug Discovery Methods
- COVID-19 Clinical Research Studies
- Monoclonal and Polyclonal Antibodies Research
- Immunotherapy and Immune Responses
- Animal Virus Infections Studies
- Viral Infections and Outbreaks Research
- Water Quality and Pollution Assessment
- Hepatitis B Virus Studies
- Machine Learning in Bioinformatics
- Antibiotic Resistance in Bacteria
- Herpesvirus Infections and Treatments
- Cellular transport and secretion
- Enzyme Production and Characterization
- Protein Hydrolysis and Bioactive Peptides
- Groundwater and Watershed Analysis
- Plant Disease Resistance and Genetics
- Transgenic Plants and Applications
- Vitamin C and Antioxidants Research
- Influenza Virus Research Studies
- Heavy metals in environment
- Bacteriophages and microbial interactions
- Plant-Microbe Interactions and Immunity
- Bartonella species infections research
University of Dhaka
2020-2025
Khulna University of Engineering and Technology
2024
Noakhali Science and Technology University
2024
Virginia Tech
2022-2023
Sylhet Agricultural University
2018-2023
National Institute of Technology
2023
Shahjalal University of Science and Technology
2015-2022
Czech Academy of Sciences, Institute of Biotechnology
2022
National Institute of Biotechnology
2022
University of Science and Technology
2022
Ebola, one of the deadliest known infectious diseases, was root epidemics in Western Africa from 2013 to 2016. Like other deadly viruses family Filoviridae with a high fatality rate, this virus also causes hemorrhagic fever. As result, Ebola (EBOV) represents threat global health. Since there are currently no effective treatments for EBOV infections, study aims identify potential natural drug candidates that may block VP40 prevent infections. The compounds were analyzed using ADMET,...
Herpes simplex virus type 1 (HSV-1) and 2 (HSV-2) cause a variety of infections including oral-facial infections, genital herpes, herpes keratitis, cutaneous infection so on. To date, FDA-approved licensed HSV vaccine is not available yet. Hence, the study was conducted to identify characterize an effective epitope based polyvalent against both types Simplex Virus. The selected proteins were retrieved from ViralZone assessed design highly antigenic epitopes by binding analyses peptides with...
This study investigates the contamination of groundwater in Dhaka City, Bangladesh, focusing on six potentially toxic elements, including As, Cu, Mn, Cr, Al, and B, due to their implications for public health as serves primary source drinking water region. 15 samples were taken into consideration was analyzed elements (As, B) using an Atomic Absorption Spectrophotometer (AAS). Arsenic (As) chromium (Cr) undetectable all samples. The average concentrations Copper (Cu), Aluminum (Al), Boron...
Here, drug repurposing and molecular docking were employed to screen approved MPP inhibitors their derivatives suggest a specific therapeutic agent for the treatment of COVID-19. The against HIV HCV prioritized, while RNA dependent Polymerase (RdRp) inhibitor remdesivir including Favipiravir, alpha-ketoamide studied as control groups. target surface hotspot was also investigated through technique. Molecular dynamics performed determine binding stability docked complexes. Absorption,...
Colistin (polymyxin E) is widely used in animal and human medicine increasingly as one of the last-resort antibiotics against Gram-negative bacilli. Due to increased use colistin treating infections caused by multidrug-resistant bacteria, resistance this antibiotic ought be monitored. The study was undertaken elucidate molecular mechanisms, genetic relationships phenotype correlations colistin-resistant isolates. Here, we report detection mcr-1 gene chicken-associated Salmonella isolates...
Bartonella bacilliformis, a causative agent of Bartonellosis or Carrión's disease, has become resistant to antibacterial agents. To suggest effective novel drug targets, comprehensive in silico subtractive genomic approach was employed the genome B. bacilliformis subsp. ver097. Different bioinformatics tools and online servers were utilized determine human homologous proteins pathogen, as well associated with common metabolic pathways pathogen host. Only seven specific pathways, which...
Zoonotic and antimicrobial-resistant Escherichia coli (hereafter, E. coli) is a global public health threat which can lead to detrimental effects on human health. Here, we aim investigate the antimicrobial resistance presence of mcr-1 gene in isolated from chicken feces. Ninety-four isolates were obtained samples collected different locations Bangladesh, identified using conventional microbiological tests. Phenotypic disk diffusion tests 20 agents performed according CLSI-EUCAST guidelines,...
Groundwater meets the majority portion of drinking water needs, particularly in rural area Bangladesh.Groundwater has been continuously contaminated by potentially harmful metals as a result natural processes well some anthropogenic activities, creating variety health impacts.The current research aimed to evaluate naturally occurring level metal contamination and human risk associated with deep groundwater Hatiya Island.Because arsenic, iron, salinity problem shallow groundwater, inhabitants...
Nipah virus (NiV), a zoonotic virus, engenders severe infections with noticeable complications and deaths in humans animals. Since its emergence, it is frightening, this has been causing regular outbreaks various countries, particularly Bangladesh, India, Malaysia. Unfortunately, no efficient vaccine or drug available now to combat baneful virus. NiV employs nucleocapsid protein for genetic material packaging, which crucial viral replication inside the host cells. The small interfering RNAs...
Multidrug-resistant Vibrio parahaemolyticus has become a significant public health concern. The development of effective drugs and vaccines against is the current research priority. Thus, we aimed to find out drug vaccine targets using comprehensive genome-based analysis. A total 4822 proteins were screened from V. proteome. Among 16 novel cytoplasmic proteins, 'VIBPA Type II secretion system protein L' Putative fimbrial Z' subjected molecular docking with 350 human metabolites, which...
As an omnipresent opportunistic bacterium, Pseudomonas aeruginosa PAO1 is responsible for acute and chronic infection in immunocompromised individuals. Currently, this bacterium on WHO's red list where new antibiotics are urgently required the treatment. Finding essential genes hypothetical proteins (EHP) can be crucial identifying novel druggable targets therapeutics. This study aimed at characterizing these EHPs analyzing subcellular physiochemical properties, PPI network, nonhomologous...
Canine parvovirus (CPV-2) is one of the most important pathogens dogs all ages, causing pandemic infections that are characterized by fatal hemorrhagic enteritis. The CPV-2 vaccine recommended as a core for pet animals. Despite intensive practice active immunization, remains global threat. In this study, multi-epitope against was designed, targeting highly conserved capsid protein (VP2) via in silico approaches. Several immunoinformatics methods, such epitope screening, molecular docking,...
Arenaviral infections often result lethal hemorrhagic fevers, affecting primarily in African and South American regions. To date, there is no FDA-approved licensed vaccine against arenaviruses treatments have been limited to supportive therapy. Hence, the study was employed design a highly immunogenic cross-reactive Arenaviridae family using reverse vaccinology approach. The whole proteome of Lassa virus (LASV), Lymphocytic Choriomeningitis (LCMV), Lujo Guanarito were retrieved assessed...