Blandine Courbière

ORCID: 0000-0002-1847-4509
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About
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Research Areas
  • Reproductive Biology and Fertility
  • Ovarian function and disorders
  • Reproductive Health and Technologies
  • Assisted Reproductive Technology and Twin Pregnancy
  • Gynecological conditions and treatments
  • Endometriosis Research and Treatment
  • Ovarian cancer diagnosis and treatment
  • Ectopic Pregnancy Diagnosis and Management
  • Uterine Myomas and Treatments
  • Sperm and Testicular Function
  • Maternal and fetal healthcare
  • Reproductive System and Pregnancy
  • Effects and risks of endocrine disrupting chemicals
  • Carcinogens and Genotoxicity Assessment
  • Gestational Trophoblastic Disease Studies
  • Maternal and Perinatal Health Interventions
  • Cancer Risks and Factors
  • Intraperitoneal and Appendiceal Malignancies
  • Renal and related cancers
  • Childhood Cancer Survivors' Quality of Life
  • Family Support in Illness
  • Growth Hormone and Insulin-like Growth Factors
  • Reproductive Health and Contraception
  • Sexual function and dysfunction studies
  • Prenatal Screening and Diagnostics

Institut de Recherche pour le Développement
2016-2025

Centre National de la Recherche Scientifique
2016-2025

Hôpital de la Conception
2015-2024

Institut Méditerranéen de Biodiversité et d'Ecologie Marine et Continentale
2015-2024

Aix-Marseille Université
2015-2024

Assistance Publique Hôpitaux de Marseille
2011-2024

Université d'Avignon et des Pays de Vaucluse
2015-2024

Institut de Microbiologie de la Méditerranée
2024

Reproductive Science Center
2024

Hôpital Nord
2004-2020

Background. Bacterial vaginosis is a risk factor for preterm birth. The various conventional methods its diagnosis are laborious and not easily reproducible. Molecular quantification have been reported recently, but the specific factors they might identify remain unclear. Methods. A prospective multicenter national study included pregnant women at of quantitative molecular tool using real-time polymerase chain reaction assay serial dilutions plasmid suspension quantified Atopobium vaginae,...

10.1093/cid/ciu966 article EN Clinical Infectious Diseases 2014-12-01

Does the live birth rate after IVF depend on etiology of diminished ovarian reserve (DOR)? outcome and are significantly impaired in women with DOR caused by a previous cystectomy for endometrioma compared idiopathic DOR. The safety surgical treatment endometriomas is being discussed terms damage to reserve. Several studies have reported poor response controlled stimulation consecutive an tubal factor infertility. Retrospective case–control study conducted aged under 40 treated our...

10.1093/humrep/dev029 article EN Human Reproduction 2015-03-03

A recent study of 17 men with decapitated spermatozoa found that 8 carried two rare SUN5 alleles, and concluded loss function causes the acephalic syndrome. Consistent this, protein localises to head-tail junction in normal spermatozoa, SUN proteins are known form links between cytoskeleton nucleus. However, six ten variants reported were missense an unknown effect on function, only one man high confidence loss-of-function (LOF) alleles: p.Ser284* homozygozity. One potential exonic splice...

10.1093/hmg/ddx200 article EN Human Molecular Genetics 2017-05-24

The aim of this study was to evaluate the long-term outcome autotransplantation vitrified warmed hemi-ovaries into ewes.Six from six ewes aged 6 12 months were vitrified. After dissection medulla, hemi-ovarian cortex stored at -196 degrees C in liquid nitrogen. Four weeks after first laparotomy, left ovary removed and vitrified-warmed hemi-ovary sutured.Plasma progesterone concentration increased a regular manner all ewes. Three pregnancies occurred, which four lambs born. delivery normal...

10.1093/humrep/dei155 article EN Human Reproduction 2005-06-24

Cerium dioxide nanoparticles (C(e)O₂ ENPs) are on the priority list of nanomaterials requiring evaluation. We performed in vitro assays mature mouse oocytes incubated with C(e)O₂ ENPs to study (1) physicochemical biotransformation culture medium; (2) ultrastructural interactions follicular cells and using Transmission Electron Microscopy (TEM); (3) genotoxicity a comet assay. DNA damage was quantified as Olive Tail Moment. show that aggregated, but their crystal structure remained stable...

10.3390/ijms141121613 article EN cc-by International Journal of Molecular Sciences 2013-10-31

STUDY QUESTIONDoes in vivo exposure to benzo(a)pyrene (BaP) induce DNA damage oocytes and cumulus cells (CCs) mice?

10.1093/humrep/det439 article EN Human Reproduction 2013-12-09

Little is known about Sheehan's syndrome (SS), even though it believed that its incidence low. The aims of this study were to determine the clinical features and diagnostic delay SS ascertain whether early signs could have allowed earlier diagnosis.All patients with diagnosed in reference units southeast France between 1980 2011 recruited for study. Data on obstetrical history, symptoms suggestive hypopituitarism, signs, hormone analysis, magnetic resonance imaging collected.Of 40 women...

10.1530/eje-13-0279 article EN European Journal of Endocrinology 2013-07-18

Due to their catalytic and oxidative properties, cerium dioxide nanoparticles (CeO2NPs) are widely used as diesel additive or promising therapy in cancerology; yet, scarce data available on toxicity, none reproductive toxicity. We showed a significant decrease of fertilization rate, assessed 1272 oocytes, during vitro (IVF) carried out culture medium containing CeO2NP at very low concentration (0.01 mg.l−1). also DNA damage induced by mouse spermatozoa oocytes 0.01 mg.l−1 using Comet assay....

10.3109/17435390.2015.1030792 article EN Nanotoxicology 2015-05-22

We aimed to develop and validate an algorithm for identifying women with polycystic ovary syndrome (PCOS) in the French national health data system. Using from system, we applied International Classification of Diseases (ICD-10) related diagnoses E28.2 PCOS among aged 18 43 years 2021. Then, developed identify using combinations clinical criteria specific drugs claims, biological exams, international classification during hospitalization, and/or registration long-term conditions. The...

10.1186/s12874-024-02447-4 article EN cc-by-nc-nd BMC Medical Research Methodology 2025-01-10
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