A5012449900- Sepsis Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Hemodynamic Monitoring and Therapy
- Nosocomial Infections in ICU
- Machine Learning in Healthcare
- Antibiotic Use and Resistance
- Thermal Regulation in Medicine
- Emergency and Acute Care Studies
- Electronic Health Records Systems
- Central Venous Catheters and Hemodialysis
- Reproductive tract infections research
- Artificial Intelligence in Healthcare
- Bacterial Identification and Susceptibility Testing
- Urinary Tract Infections Management
- Cardiac, Anesthesia and Surgical Outcomes
- Artificial Intelligence in Healthcare and Education
- Biomedical and Engineering Education
- Family and Patient Care in Intensive Care Units
- Anesthesia and Sedative Agents
- Syphilis Diagnosis and Treatment
- Medical Coding and Health Information
- Clinical practice guidelines implementation
- Liver Disease Diagnosis and Treatment
- Healthcare Regulation
Cincinnati Children's Hospital Medical Center
2024
University of Cincinnati
2024
University of Cincinnati Medical Center
2024
Massachusetts Institute of Technology
2017-2024
HealthPoint Communications
2022
Hospital Israelita Albert Einstein
2012-2021
Healthpoint
2021
Harvard–MIT Division of Health Sciences and Technology
2017-2020
UnityPoint Health
2020
National Institutes of Health
2019
Objectives: To evaluate the relative validity of criteria for identification sepsis in an ICU database. Design: Retrospective cohort study adult admissions from 2008 to 2012. Setting: Tertiary teaching hospital Boston, MA. Patients: Initial admission all patients noncardiac surgical ICUs. Interventions: Comparison five different algorithms retrospectively identifying sepsis, including Sepsis-3 criteria. Measurements and Main Results: 11,791 23,620 (49.9%) met study. Within this subgroup,...
Whether critical care improvements over the last 10 years extend to all hospitals has not been described.
Abstract Background Penicillin's long-standing role as the reference standard in syphilis treatment has led to global reliance. However, this dependence presents challenges, prompting need for alternative strategies. We performed a systematic literature review and meta-analysis evaluate efficacy of these treatments against nonneurological syphilis. Methods searched MEDLINE, Cumulative Index Nursing Allied Health Literature, Embase, Cochrane, Scopus, Web Science from database inception 28...
Objectives The acute respiratory distress syndrome (ARDS) is a heterogeneous condition, and identification of subphenotypes may help in better risk stratification. Our study objective to identify ARDS using new simpler methodology readily available clinical variables. Setting This retrospective Cohort Study trials. Data from the US ARDSNet trials international ART trial. Participants 3763 patients data sets 1010 set. Primary secondary outcome measures primary was 60-day or 28-day mortality,...
Abstract Illness severity scores are regularly employed for quality improvement and benchmarking in the intensive care unit, but poor generalization performance, particularly with respect to probability calibration, has limited their use decision support. These models tend perform worse patients at a high risk mortality. We hypothesized that sequential modeling approach wherein an initial regression model assigns all deemed then have quantified by second, high-risk-specific, would result...
Introduction Current guidelines and consensus recommend arterial venous samples as equally acceptable for blood glucose assessment in point-of-care devices, but there is limited evidence to support this recommendation. We evaluated the accuracy of two devices bedside measurements using arterial, fingerstick catheter ICU patients, assessed which factors could impair their accuracy. Methods 145 patients from a 41-bed adult mixed-ICU, tertiary care hospital were prospectively enrolled....
The creation of medical notes in software applications poses an intrinsic problem workflow as the technology inherently intervenes processes collecting and assembling information, well production a data-driven note that meets both individual healthcare system requirements. In addition, writing currently available electronic health records (EHRs) do not function to support decision making any substantial degree. We suggest artificial intelligence (AI) could be utilized facilitate workflows...
Background Studies in patients receiving invasive ventilation show important differences use of low tidal volume (V T ) (LTVV) between females and males. The aims this study were to describe temporal changes V determine what factors drive the sex difference LTVV. Methods findings This is a posthoc analysis 2 large longitudinal projects 59 ICUs United States, ‘Medical information Mart for Intensive Care III’ (MIMIC III) ‘eICU Collaborative Research DataBase’. proportion under LTVV (median...
Approximately 150 million central venous catheters (CVC) are used each year in the United States. Catheter-related bloodstream infections (CR-BSI) one of most important complications (CVCs). Our objective was to compare in-hospital mortality when catheter is removed or not patients with CR-BSI.We reviewed all episodes CR-BSI that occurred our intensive care unit (ICU) from January 2000 December 2008. The standard method defined as a patient CVC and at least positive blood culture obtained...
Severity of illness scores rest on the assumption that patients have normal physiologic values at baseline and with similar severity same degree deviation from their usual state. Prior studies reported differences in physiology, including laboratory markers, between obese weight individuals, but these not been analyzed ICU. We compared pertinent ICU test results patients, adjusted for illness.Retrospective cohort study a large database.Tertiary teaching hospital.Obese who had documented 3...
Among patients with vasodilatory shock, gene expression scores may identify different immune states. We aimed to test whether such are robust in identifying patients' state and predicting response hydrocortisone treatment shock.We selected genes generate continuous define previously established subclasses of sepsis. used these a patient's state. evaluated the potential for states assess differential effect two randomized clinical trials versus placebo initially identified associated...