Monoaldehydes, due to natural origin and therapeutic activity, have attracted great attention for their ability crosslink chitosan hydrogels biomedical applications. However, most studies focused on single-component hydrogels. In this work, chitosan-based hydrogels, crosslinked the first time with 2,3,4-trihydroxybenzaldehyde (THBA), were modified pectin (PC), bioactive glass (BG), rosmarinic acid (RA). All of these not only involved in crosslinking, but also modulated properties or imparted...

In this study, multilayer microcapsules (two-layer and four-layer) based on furcellaran (FUR) chitosan (CHIT) were produced, enclosing a tripeptide with an antioxidant effect-glutathione-in different concentrations. addition, for the first time, empty, four-layer microcapsule CHIT FUR (ECAPS) was obtained, which can be used to contain sensitive, active substances of hydrophobic nature. Layering monitored using zeta potential, presence resulting capsules confirmed by SEM imaging. current we...

Abstract Cruciferous vegetables are a valuable source of ingredients with health benefits. The most characteristic compounds cruciferous identified anticancer properties glucosinolates. Young shoots and sprouts red cabbage becoming popular fresh food rich in nutrients bioactive compounds. objective this research was to determine, for the first time comprehensive approach, whether young headed better selected glucosinolates human diet comparison vegetable at full maturity. proximate...

The increasing knowledge on health benefit properties of plant origin food ingredients supports recommendations for the use edible plants in prevention diet related diseases, including cancer. beneficial effects young shoots red cabbage can be attributed to their mixture phytochemicals possessing antioxidant and potential anticancer activity. objective this study was compare content bioactive compounds, HPLC analysis polyphenols activity vegetable at full maturity. vitamin C juices obtained...

Natural polysaccharides, including hyaluronic acid, find a wide range of applications in biomedical sciences. There is growing interest nanocomposites containing acid and nanoparticles such as nanometals or graphene. In this study, we prepared foils pure sodium hyaluronate nanosilver, graphene oxide, nanosilver/graphene oxide characterized their properties. UV-vis spectroscopy scanning electron microscopy (SEM) confirmed the formation 10–20 nm silver nanoparticles. The structural changes...

Abstract In this study, the possibility of modifying a multi-layer biopolymer active system to reduce permeability gases biodegradable material with potential application in food technology was analysed. A four-layer film used, wherein initial two layers comprised furcellaran, whilst subsequent were mixture chitosan and gelatin. The modified ingredients, including silver nanoparticles (AgNPs), montmorillonite, curcumin-capsaicin gelatin hydrolysate. formed an integrated, semi-rigid packaging...

In our previous study, we showed that fatty acids from CLA-enriched egg yolks (EFA-CLA) reduced the proliferation of breast cancer cells; however, molecular mechanisms their action remain unknown. current used MCF-7 cell line to determine effect EFA-CLA, as potential ligands for peroxisome proliferator-activated receptors (PPARs), on identified in silico PPAR-responsive genes: BCAR3 , TCF20 WT1 ZNF621 and THRB (transcript TR β 2). Our results EFA-CLA act PPAR with agonistic activity all...

Modern medicine is struggling with the problem of fully effective treatment neoplastic diseases despite deploying innovative chemotherapeutic agents. Therefore, undertaking cancer-prevention measures, such as proper eating habits, should be strongly recommended. The present research aimed to compare effects juice from young shoots beetroot compared root at full maturity on human breast cancer and normal cells. shoots, both in native digested form, was most often a significantly stronger...

Fatty acids from conjugated linoleic acid (CLA)-enriched egg yolk suppressed the viability of MCF-7 cancer line more effectively than non-enriched yolk. Herein we aimed to determine molecular mechanisms by analysing expression and activation proteins involved in cellular stress apoptosis signaling.Forty-eight Isa Brown laying hens (26-week-old) were fed a fortified (0.75% CLA) or control diet (0% for 4 months. Collected eggs used obtain CLA-enriched (EFA-CLA) (EFA) fatty extracts treatment...

Prostate cancer is one of the most common cancers in men. Recent dietary and epidemiological studies have suggested benefit intake cruciferous vegetables lowering incidence cancer. The health promoting effects red cabbage are attributed to their mixture phytochemicals known for antioxidant anticancer activity. In current study, we investigated whether young shoots mature had any effect on prostate cell lines (DU145 LNCaP). Attempts were also made identify potential molecular mechanism(s) by...

The conjugated linoleic acid (CLA) diene is a biologically active compound with proven health-promoting effects. In terms of anticancer properties, it has been shown that CLA reduces the proliferation cancer cells. this study, demonstrated mixture fatty acids, isolated from chicken egg yolk enriched in isomers by biofortification, (by 30.5%) human melanoma cells line WM793 to greater extent than acids not containing these isomers. At same time, tested mixtures show no effect on normal BJ...

Melanoma malignum is considered the most dangerous form of skin cancer, characterized by exceptional resistance to many conventional chemotherapies. The aim study was evaluate effect NutramilTM Complex (NC) – Food for Special Medical Purpose (FSMP), on two types melanoma cell lines, primary WM115 and malignant WM266-4. 24h after seeding, growth medium replaced with a containing encoded treatments NC or NC-CC (NutramilTM without calcium caseinate) at various concentrations. Cells were treated...

Background/Objectives: Melanoma malignum is considered the most dangerous form of skin cancer, characterized by exceptional resistance to many conventional chemotherapies. The aim this study was evaluate effect NutramilTM Complex (NC)—Food for Special Medical Purpose (FSMP), on two types melanoma cell lines, primary WM115 and malignant WM266-4. Methods: At 24 h after seeding, growth medium replaced with a containing encoded treatments NC or NC-CC (NutramilTM without calcium caseinate) at...

Consuming food containing ingredients with a documented impact on lipid metabolism can help fight overweight and obesity. The simplest way to reduce the level of fatty acids is block their synthesis or increase rate degradation. This study aimed determine effect resveratrol, cis-9, trans-11 conjugated linoleic acid (CLA), trans-10, cis-12 CLA, various variants combinations de novo biosynthesis in 3T3-L1 adipocytes. influence above-mentioned bioactive substances cells grown under standard...

Sweet alyssum (Lobularia maritima L.) is known as an insectary plant with great potential in enhancing the occurrence and diversity of beneficial insects different crops. However, agronomic aspects introduction this are still not fully recognized. Field studies aimed at assessing entomological relationships quasi-coordinate system focused on evaluating impact sweet a companion broad bean (Vicia faba L.) cultivation prevalence black aphid (Aphis fabae Scop.) its...

NutramilTM Complex is a multicomponent food product that meets the requirements of for special medical purpose. As complete, high-energy diet it consists properly balanced nutrients, vitamins and minerals. The aim this study was to assess effect on breast prostate carcinoma cells. Our results showed reduced viability proliferation cancer cells process associated with induction apoptosis via activation caspase signalling. Data elevated levels p53 tumour suppressor, up-regulation p38 MAPK SAPK...

PPAR receptors are ligand-dependent transcription factors activated in response to various small lipophilic ligands controlling the expression of different genes involved cellular differentiation, development, metabolism, and tumorigenesis. Unexpectedly, our previous studies have shown that single plasmid-based PPARs under control CMV promoter/enhancer was significantly elevated presence agonists. Here we show reporters controlled by promoter/enhancer, contain three internal non-canonical...