A5022991926- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Infective Endocarditis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Cardiac pacing and defibrillation studies
- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Orthopaedic implants and arthroplasty
- Cardiac Arrhythmias and Treatments
- Mechanics and Biomechanics Studies
- Shoulder Injury and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Medical Imaging and Pathology Studies
- Mechanical Systems and Engineering
- Mechanical Circulatory Support Devices
- Engineering Diagnostics and Reliability
- Cardiac and Coronary Surgery Techniques
The Wallace H. Coulter Department of Biomedical Engineering
2012-2022
Georgia Institute of Technology
2012-2022
Active Implants (United States)
2018-2021
Momentum Research
2017
Landscape Research Group
2016
Exponent (United States)
2014
Mitral annular calcification (MAC) involves calcium deposition in the fibrous annulus supporting mitral valve (MV). When extends onto leaflets, opening can be restricted. The influence of MAC MV geometry on Doppler gradients is unknown. This study describes a novel methodology to rapid-prototype subject-specific MVs. Replicated valves were used assess effects distorted annular-leaflet Doppler-derived, transmitral comparison direct pressure measurements and determine if vary according...
Computational models for the heart's mitral valve (MV) exhibit several uncertainties that may be reduced by further developing these using ground-truth data-sets. This study generated a data-set quantifying effects of isolated annular flattening, symmetric dilatation, papillary muscle (PM) displacement and asymmetric PM on leaflet coaptation, regurgitation (MR) anterior strain. MVs were mounted in an vitro left heart simulator tested under pulsatile haemodynamics. Mitral coaptation length,...
This study quantitatively evaluated the phasic right heart morphology of candidate patients for a transcatheter tricuspid valve intervention (N=32) and subjects with trace to no regurgitation (N = 14).Cardiac computed tomography angiography (CCTA) transthoracic/transesophageal echocardiography (TTE/TEE) images were analyzed using dedicated research clinical software. Using CCTA, atrial ventricular volumes, annulus dimensions, annulus-to-right coronary artery (RCA) distances, circumferential...
A clinical study comparing the hemodynamic outcomes of transcatheter mitral valve replacement (TMVR) with vs. without Laceration Anterior Mitral leaflet to Prevent Outflow Obstruction (LAMPOON) has never been designed nor conducted.To quantify impact LAMPOON in TMVR using patient-specific computational (in silico) models.Eight subjects from investigational device exemption trial were included who had acceptable computed tomography (CT) data for analysis. All anticipated be at prohibitive...