Marek Durlik

ORCID: 0000-0002-1905-6114
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About
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Research Areas
  • Pancreatic and Hepatic Oncology Research
  • Organ Transplantation Techniques and Outcomes
  • Renal Transplantation Outcomes and Treatments
  • Pancreatitis Pathology and Treatment
  • Transplantation: Methods and Outcomes
  • Mesenchymal stem cell research
  • Organ and Tissue Transplantation Research
  • Hematopoietic Stem Cell Transplantation
  • Lymphatic System and Diseases
  • Liver Disease and Transplantation
  • Cancer Genomics and Diagnostics
  • Diabetes and associated disorders
  • Organ Donation and Transplantation
  • Pancreatic function and diabetes
  • Renal and Vascular Pathologies
  • Neuroendocrine Tumor Research Advances
  • Gastrointestinal disorders and treatments
  • COVID-19 Clinical Research Studies
  • Gallbladder and Bile Duct Disorders
  • Renal cell carcinoma treatment
  • Inflammatory Bowel Disease
  • COVID-19 and healthcare impacts
  • Immunotherapy and Immune Responses
  • Prenatal Screening and Diagnostics
  • Long-Term Effects of COVID-19

Ministry of Interior and Administration
2012-2024

Central Clinical Hospital
2013-2023

Postgraduate School of Molecular Medicine
2020-2023

Medical University of Warsaw
2008-2023

Centralny Szpital Kliniczny
2011-2021

Polish Academy of Sciences
2011-2020

Mossakowski Medical Research Institute, Polish Academy of Sciences
2012-2019

Hungarian Academy of Sciences
2012

National Cheng Kung University Hospital
2012

Andijan State Medical Institute
2012

Several COVID-19 convalescents suffer from the post-acute COVID-syndrome (PACS)/long COVID, with symptoms that include fatigue, dyspnea, pulmonary fibrosis, cognitive dysfunctions or even stroke. Given scale of worldwide infections, long-term recovery and integrative health-care in nearest future, it is critical to understand cellular molecular mechanisms as well possible predictors longitudinal post-COVID-19 responses convalescent individuals. The immune system T cell alterations are...

10.3389/fimmu.2022.886431 article EN cc-by Frontiers in Immunology 2022-06-10

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Eder P, Łodyga M, Gawron-Kiszka et al. Guidelines for the management of ulcerative colitis. Recommendations Polish Society Gastroenterology and National Consultant in Gastroenterology. Review/Przegląd Gastroenterologiczny. 2023;18(1):1-42. doi:10.5114/pg.2023.125882. APA Eder, P., Łodyga, M., Gawron-Kiszka, Dobrowolska, A., Gonciarz, & Hartleb, M. (2023). Gastroenterologiczny, 18(1), 1-42....

10.5114/pg.2023.125882 article EN Gastroenterology Review 2023-01-01

Background: The manual lymphatic drainage in lymphedema has proved to be successful; however, this method cannot applied millions of patients around the world. only solution is offer inexpensive, easily accessible mechanical devices for pneumatic compression (IPC). These should designed on parameters edema fluid hydromechanics. Recent data point high pressures and long time compression. Aim: To validate effects 3 years daily pressure, inflation IPC therapy terms decrease limb...

10.1089/lrb.2013.0033 article EN Lymphatic Research and Biology 2014-06-01

Pneumatic compression of tissues with lymph stasis is, aside from the manual massage, a commonly used therapeutic modality in limb lymphedema. A number pneumatic devices have been constructed. There is lack reports comparative studies determining inflation pressure levels, inflation/deflation cycle times, and total pumping times. Aim: We tried to answer question how high long timing should be applied soft reach tissue fluid (TF) head above 30 mmHg, necessary initiate proximal flow. Methods:...

10.1089/lrb.2013.0016 article EN Lymphatic Research and Biology 2013-12-01

These recommendations refer to the current management in pancreatic ductal adenocarcinoma (PDAC), a neoplasia characterised by an aggressive course and extremely poor prognosis. The regard diagnosis, surgical, adjuvant palliative treatment, with consideration given endoscopic surgical methods. A vast majority of statements are based on data obtained clinical studies experts' PDAC management, including following guidelines: International Association Pancreatology/European Pancreatic Club...

10.5114/pg.2019.83422 article EN cc-by-nc-sa Gastroenterology Review 2019-01-01

Research over the last twenty years has yielded much insight into pancreatic cancer biology, but it neither improved diagnostics methods nor way of treatment. The question remains as to what critical deciding factor is in making such an aggressive disease.Pancreatic tumor tissue came from 36 patients. To assess lymphatic vessels color lymphangiography and immunohistochemistry were used. Activity matrix metalloproteinases was studied with gel situ zymography. Expression growth factors...

10.7150/jca.4537 article EN cc-by-nc Journal of Cancer 2012-01-01

Pancreatic adenocarcinoma is the fourth most common cancer occurring in both women and men. In Poland, within past ten years number of deaths from pancreatic increased by 29%.The aim study was to determine correlation between activity metalloproteinase (MMP) 2 9 progression aggressiveness cancer.Tissue samples were collected 36 patients with diagnosed who underwent Whipple resection. Tumor tissues analyzed gel zymography, zymography situ immunohistochemistry.The MMPs found mainly cells....

10.2478/v10035-012-0064-6 article EN Polish Journal of Surgery 2012-01-01

Background: The mobile intercellular fluid flowing to and in the lymphatics contains filtered plasma products substances synthesized excreted by tissue cells. Among them are signaling proteins such as cytokines, chemokines, enzymes, growth factors. They act locally autocrine paracrine systems regulating cell metabolism, proliferation, formation of ground matrix. play an immunoregulatory role infections, wound healing, tumor growth. Methods Results: In this study we measured concentration...

10.1089/lrb.2013.0014 article EN Lymphatic Research and Biology 2013-12-01

Biological medical products are drugs whose active components produced only by living, genetically modified organisms or live cell cultures. Patents and exclusivity for most biopharmaceuticals has either expired will expire soon, which enables biotechnological companies to introduce similar biological products. The problem of replacing a medicine with biosimilar in the course therapy remains open. In this statement, Working Group Polish National Consultant Gastroenterology, absence data...

10.5114/pg.2014.40842 article EN cc-by-nc-sa Gastroenterology Review 2014-01-01

Background. Bone marrow (BM) transplantation for treatment of hematological and solid malignancies is routinely carried out in conjunction with radio- chemotherapy. Many patients achieve complete remission the malignant process; however, their lymphohematopoietic recovery remains most cases incomplete. This probably due to functional changes recipient BM stromal cells subsequent myeloablative therapy. Transplantation hematopoietic a spatial relationship would give an insight into kinetics...

10.1097/00007890-199907270-00007 article EN Transplantation 1999-07-01

Introduction. In spite of intensive research during many years, pancreatic adenocarcinoma remains one the deadliest cancers. The surgical intervention main possibility treatment because chemotherapy and radiotherapy has a minimal impact on long-term survival. We are still looking for weak points this devastating disease. Materials Methods. Pancreatic tumor tissue samples were collected from 36 patients. Immunohistochemistry staining was used to evaluate expression growth factors immune...

10.1155/2012/585674 article EN cc-by Gastroenterology Research and Practice 2012-01-01

The presented recommendations concern the current management of acute pancreatitis. relate to diagnostics and treatment early late phases pancreatitis complications disease taking into consideration surgical endoscopic methods. All were subjected voting by members Working Group Polish Pancreatic Club, who evaluated them every single time on a five-point scale, where A means full acceptance, B acceptance with certain reservation, C serious D rejection reservation E rejection. results vote,...

10.5114/pg.2016.60251 article EN Gastroenterology Review 2016-01-01

Background: Infections and inflammation of the lower limb skin, soft tissues, vessels are more common than in other body regions. The aim was to determine whether cryptic bacteria dwelling deep tissues cause. Methods: We performed bacteriologic studies specimens harvested from arteries amputated ischemic legs, leg varices, tissue fluid/lymph lymphatics lymphedema. Results: Calf contained isolates 61% femoral 36%, whereas normal cadaveric organ donors' 11%. Bacterial deoxyribonucleic acid...

10.1089/sur.2014.019 article EN Surgical Infections 2015-06-01

Background: pancreatic ductal adenocarcinoma (PDAC) is the seventh leading cause of cancer-related deaths with increasing incidence and link to onset diabetes mellitus (DM). The aim this study describe prevalence DM among patients diagnosis PDAC, analyse association between occurrence clinicopathological factors, detect variables influencing overall survival. Methods: a retrospective analysis medical records was performed. were divided into non-DM (n = 101) 74) groups. Statistical usage...

10.3390/cancers14122840 article EN Cancers 2022-06-08

Background.A total of 148 surgeries were performed in our center on patients with pancreatic cancer 2020.In 2019, 263 such procedures (77.7% more) this facility. Objectives.To analyze the impact coronavirus disease 2019 (COVID-19) surgery type, number and outcome center. Materials methods.Retrospective data analysis medical documentation a hospital database from January till December 2020.Results.In 2020, we observed an increase tumors localized tail pancreas (P) -29 cases (19.9%) 2020...

10.17219/acem/144134 article EN cc-by Advances in Clinical and Experimental Medicine 2022-02-02

This article describes the latest diagnostic and therapeutic recommendations in chronic pancreatitis, developed by Working Group of Polish Society Gastroenterology Pancreas Club. The refer to diagnosis autoimmune conservative management, treatment pain, exocrine endocrine pancreatic insufficiency, pancreatitis endoscopic surgical methods, oncological surveillance pancreatitis. paper refers published 2011, which have been updated supplemented. All were voted experts Club, who evaluated them...

10.5114/pg.2018.78067 article EN cc-by-nc-sa Gastroenterology Review 2018-01-01

BACKGROUND Vascular failures are serious complications in pancreas transplantation. Open surgery is a reliable and quick intervention method, but it carries risk of infection bleeding. Endovascular procedures rare among patients after SPK, becoming more frequently used. One the main risks endovascular approach that renal function impairment caused by contrast agent. MATERIAL AND METHODS We performed retrospective analysis 200 transplanted pancreases at our center over last 14 years. The...

10.12659/aot.912005 article EN Annals of Transplantation 2019-04-12

10.1016/j.transproceed.2018.02.097 article EN Transplantation Proceedings 2018-03-18

The therapeutic intermittent pneumatic compression (IPC) pressures are usually set arbitrarily at levels between 40 and 60 mmHg. However, it is not known how much force has been transferred to edema fluid. There a need know high fluid should be generated evacuate the stagnant externally applied dissipates in hard tissues only portion of conveyed tissue Simultaneous measuring using deep tonometry recording under tonometer would give hints therapist or patient IPC mobilize fluid.(1) To...

10.1089/lrb.2016.0069 article EN Lymphatic Research and Biology 2017-07-31

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Eder P, Łodyga M, Łykowska-Szuber L, et al. Guidelines for the management of ulcerative colitis. Recommendations Working Group Polish National Consultant in Gastroenterology and Society Gastroenterology. Review/Przegląd Gastroenterologiczny. 2013;8(1):1-20. doi:10.5114/pg.2013.34176. APA Eder, P., Łodyga, M., Łykowska-Szuber, L., Bartnik, W., Durlik, & Gonciarz, M. (2013). Gastroenterologiczny, 8(1), 1-20....

10.5114/pg.2013.34176 article EN Gastroenterology Review 2013-01-01
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