Katarzyna Kuśnierz

ORCID: 0000-0001-8374-028X
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About
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Research Areas
  • Pancreatic and Hepatic Oncology Research
  • Neuroendocrine Tumor Research Advances
  • Lung Cancer Research Studies
  • Gastrointestinal Tumor Research and Treatment
  • Esophageal and GI Pathology
  • Gastric Cancer Management and Outcomes
  • Gastrointestinal disorders and treatments
  • Pancreatitis Pathology and Treatment
  • Cancer Diagnosis and Treatment
  • Neuroblastoma Research and Treatments
  • Cancer Genomics and Diagnostics
  • Bariatric Surgery and Outcomes
  • Multiple and Secondary Primary Cancers
  • Gallbladder and Bile Duct Disorders
  • Cancer, Lipids, and Metabolism
  • Renal cell carcinoma treatment
  • Surgical Sutures and Adhesives
  • Colorectal Cancer Surgical Treatments
  • Intestinal and Peritoneal Adhesions
  • Colorectal Cancer Treatments and Studies
  • Reconstructive Surgery and Microvascular Techniques
  • Esophageal Cancer Research and Treatment
  • Hedgehog Signaling Pathway Studies
  • Metastasis and carcinoma case studies
  • Genetic factors in colorectal cancer

Medical University of Silesia
2014-2024

Vilnius University Hospital Santariskiu Klinikos
2023

Lasy Państwowe
2012

Górnośląskie Centrum Medyczne
2008

W ostatnim czasie obserwuje się większe zainteresowanie rzadkimi nowotworami neuroendokrynnymi żołądkowo-jelitowo-trzustkowymi (GEP NEN). Wykrywalność nowotworów neuroendokrynnych w ostatnich latach wzrosła. Ponad 50% GEP NEN stanowią rakowiaki, które najczęściej są znajdowane przypadkowo podczas zabiegu operacyjnego jelicie cienkim i wyrostku robaczkowym oraz momencie rozpoznania przerzutów odległych, głównie do wątroby. Istnieje konieczność współdziałania specjalistów różnych dziedzin...

10.5603/ep.2013.0028 article PL Endokrynologia Polska 2014-01-03

Continuous progress in the diagnostics and treatment of neuroendocrine neoplasms (NENs), emerging results new clinical trials, guidelines issued by medical societies have prompted experts from Polish Network Neuroendocrine Tumours to update 2017 recommendations regarding management neoplasms. This article presents general for NENs, resulting findings participating Fourth Round Table Conference, entitled "Polish Guidelines Diagnostics Treatment Neoplasms gastrointestinal tract, Żelechów, June...

10.5603/ep.a2022.0049 article EN cc-by-nc-nd Endokrynologia Polska 2022-06-30

Progress in the diagnostics and therapy of gastro-entero-pancreatic (GEP) neuroendocrine neoplasms (NEN), published results new randomised clinical trials, guidelines issued by European Neuroendocrine Tumour Society (ENETS) have led Polish Network Tumours to update 2013 regarding management these neoplasms. We present general recommendations for NENs, developed experts during Third Round Table Conference - Diagnostics neoplasms: view current recommenda-tions, which took place December 2016...

10.5603/ep.2017.0015 article EN cc-by-nc-nd Endokrynologia Polska 2017-05-08

Polish recommendations regarding management of patients suffering from neuroendocrine tumors small intestine and appendix are presented. Small intestine, especially ileum represent most common origin these tumors. Majority them well differentiated grow slowly. Rarely, they less with fast growth poor prognosis. Symptoms atypical, diagnosis could be often accidental. In 4-10% typical symptoms carcinoid syndrome present. Chromogranin A is useful in the laboratory diagnostics, urinary excretion...

10.5603/ep.2013.0029 article EN Endokrynologia Polska 2014-01-03

In this paper, we present the current guidelines for diagnostics and management of pancreatic neuroendocrine neoplasms (PanNENs) developed by Polish experts providing care these patients in everyday clinical practice. oncological diagnostics, addition to biochemical tests, molecular identification with use NETest liquid biopsy circulating microRNAs is gaining importance. Both anatomical functional examinations (including new radiopharmaceuticals) are used imaging diagnostics....

10.5603/ep.a2022.0050 article EN cc-by-nc-nd Endokrynologia Polska 2022-06-30

W niniejszej pracy przedstawiono uaktualnione zalecenia grupy ekspertów Polskiej Sieci Guzów Neuroendokrynnych dotyczące zasad postępowania w nowotworach neuroendokrynnych żołądka i dwunastnicy z uwzględnieniem gastrinoma . Omówiono epidemiologię, patogenezę obraz kliniczny tych nowotworów. Przedstawiono diagnostycznego, uwzględ­nieniem diagnostyki biochemicznej, histopatologicznej oraz lokalizacyjnej. także zasady terapeutycznego, tym leczenie endoskopowe chirurgiczne, omówiono możliwości...

10.5603/ep.2017.0016 article PL cc-by-nc-nd Endokrynologia Polska 2017-05-08

Neuroendocrine neoplasms/tumours (NENs/NETs) of the large intestine are detected increasingly often, especially rectal tumours, which is probably associated with widespread use screening colonoscopy. There a growing body evidence supporting thesis that NENs rectum and colon two different diseases. Rectal usually small lesions, low to moderate histological malignancy, good prognosis, most may be treated endoscopically. colon, however, often aggressive, poorly differentiated, poor or...

10.5603/ep.2017.0019 article EN cc-by-nc-nd Endokrynologia Polska 2017-05-08

There is a substantial unmet clinical need for an accurate and effective blood biomarker neuroendocrine neoplasms (NEN). We therefore evaluated, under real-world conditions in ENETS Center of Excellence (CoE), the utility NETest as liquid biopsy compared its with chromogranin A (CgA) measurement.The cohorts were: gastroenteropancreatic NEN (GEP-NEN; n = 253), bronchopulmonary (BPNEN; 64), thymic (n 1), colon cancer 37), non-small-cell lung (NSCLC; 63), benign disease 59), controls 86). In...

10.1159/000508106 article EN Neuroendocrinology 2020-04-24

We present revised diagnostic and therapeutic guidelines for the management of pancreatic neuroendocrine neoplasms (PNENs) proposed by Polish Network Neuroendocrine Tumours.These refer to biochemical (determination specific nonspecific markers) imaging diagnostics (EUS, CT, MR, radioisotope examination with a 68Ga or 99Tc labelled somatostatin analogue).A histopathological diagnostic, which determines further patients PNENs, must be necessarily confirmed immunohistochemical tests. PNENs...

10.5603/ep.2013.0031 article EN Endokrynologia Polska 2014-01-03

W pracy przedstawiono uaktualnione polskie zalecenia postępowania z chorymi na nowotwory neuroendokrynne (NEN) jelita cienkiego i wyrostka robaczkowego. Jelito cienkie, a w szczególności jelito kręte, należą do najczęstszych lokalizacji tych nowotworów. Większość nich to wysokozróżnicowane wolno rosnące; rzadko są raki neuroendokrynne. Ich objawy mogą być nietypowe, rozpoznanie opóźnione albo przypadkowe. Zapalenie robaczkowego jest najczęściej pierwszą manifestacją NEN o tym...

10.5603/ep.2017.0018 article PL cc-by-nc-nd Endokrynologia Polska 2017-05-08

Updated Polish recommendations for the management of patients with neuroendocrine neoplasms (NENs) small intestine (SINENs) and appendix (ANENs) are presented here. The intestine, especially ileum, is one most common locations these neoplasms. Most them well-differentiated slow-growing tumours; uncommonly - carcinomas. Their symptoms may be untypical their diagnosis delayed or accidental. Najczęściej pierwszą manifestacją ANEN jest jego ostre zapalenie. Typical carcinoid syndrome occur in...

10.5603/ep.a2022.0052 article EN cc-by-nc-nd Endokrynologia Polska 2022-06-30

W niniejszej publikacji przedstawiono zaktualizowane zalecenia dotyczące diagnostyczno-terapeutycznego postępowania w nowo­tworach neuroendokrynnych trzustki (PNEN) zaproponowane przez Polską Sieć Guzów Neuroendokrynnych. Zawierają one nowe dane uzyskane latach 2013–2016, które albo potwierdziły wcześniejsze wytyczne, doprowadziły do zmian lub utworzenia dodatkowych zaleceń. diagnostyce duże znaczenie mają badania biochemiczne, obrazowe (anatomiczne i czynnościowe), jak również rozpoznanie...

10.5603/ep.2017.2016 article PL cc-by-nc-nd Endokrynologia Polska 2017-05-08

The presented recommendations concern the current management of acute pancreatitis. relate to diagnostics and treatment early late phases pancreatitis complications disease taking into consideration surgical endoscopic methods. All were subjected voting by members Working Group Polish Pancreatic Club, who evaluated them every single time on a five-point scale, where A means full acceptance, B acceptance with certain reservation, C serious D rejection reservation E rejection. results vote,...

10.5114/pg.2016.60251 article EN Gastroenterology Review 2016-01-01

(1) Background: The choice of appropriate surgical suture during operation is great significance. Currently, there are no objective studies regarding the resistance commonly used sutures in biliary tract surgery. (2) Methods: This fact leads one to conduct research concerning (Polydioxanone, Poliglecaprone, Poliglactin 910, and their analogues coated with antibacterial triclosan) environment sterile contaminated bile pancreatic juice. Tensile strength was tested at days 0, 7, 14, 21, 28...

10.3390/biomedicines10051053 article EN cc-by Biomedicines 2022-05-02

Nowotwory neuroendokrynne (NENs) jelita grubego stanowią 20% wszystkich nowotworów neuroendokrynnych. Najczęstszą ich lokalizacją jest odbytnica. są wykrywane coraz częściej i liczba ta będzie wzrastać z uwagi na powszechność wykonywania kolonoskopii, w tym badań przesiewowych oraz usuwanie wykrytych zmian. W pracy przedstawiono aktualne zalecenia dotyczące diagnostyki terapii NEN grubego, uwzględnieniem biochemicznej, patomorfologicznej, nowych technik obrazowania leczenia endoskopowego,...

10.5603/ep.2013.0032 article PL Endokrynologia Polska 2014-01-03

Most pancreatic neuroendocrine tumors (PNETs) are indolent, while ductal adenocarcinomas (PDACs) particularly aggressive. To elucidate the basis for this difference and to establish biomarkers, by using deep sequencing, we analyzed somatic variants across coding regions of 409 cancer genes measured mRNA/miRNA expression in nine PNETs, eight PDACs, four intestinal (INETs). There were 153 unique considered pathogenic or likely pathogenic, found 50, 57, 24 INETs, respectively. Ten 11 contained...

10.3390/ijms21124470 article EN International Journal of Molecular Sciences 2020-06-23

AMA Kusnierz K, Mrowiec S, Lampe P. Results of surgical management renal cell carcinoma metastatic to the pancreas. Contemporary Oncology/Współczesna Onkologia. 2015;19(1):54-59. doi:10.5114/wo.2014.45306. APA Kusnierz, K., Mrowiec, S., & Lampe, (2015). Onkologia, 19(1), 54-59. https://doi.org/10.5114/wo.2014.45306 Chicago Katarzyna, Slawomir and Pawel Lampe. 2015. "Results pancreas". Onkologia 19 (1): Harvard pp.54-59. MLA Katarzyna et al. pancreas." vol. 19, no. 1, 2015, pp. Vancouver

10.5114/wo.2014.45306 article EN Współczesna Onkologia 2014-11-12

Abstract Background NETest, a novel multi-gene liquid biopsy has utility in neuroendocrine tumor (NET) diagnosis and identification of residual disease. We independently assessed the NETest to diagnose gastric neoplasms (GNENs) identify micro- macroscopic Methods Cohorts comprised histologically confirmed GNENs at biopsy, n = 46; GNETs Type 1: 42 (32 NET G1, 10 G2), GNET 3: 1 well-differentiated G3, carcinomas (NECs) ( 3), controls 63). Disease status sampling was by gastroscopy, histology...

10.1186/s12876-020-01348-2 article EN cc-by BMC Gastroenterology 2020-07-23

Pancreatic cancer is the most common pancreatic solid malignancy with an aggressive clinical course and low survival rate. There are a limited number of reliable prognostic biomarkers need to understand pathogenesis tumors; neuroendocrine (PNET) ductal adenocarcinomas (PDAC) encouraged us analyze serum metabolome tumors disturbances in metabolism PDAC PNET.Using AbsoluteIDQ® p180 kit (Biocrates Life Sciences AG, Innsbruck, Austria) liquid chromatography-mass spectrometry (LC-MS), we...

10.3390/cancers15123242 article EN Cancers 2023-06-19

This paper presents the updated Polish Neuroendocrine Tumour Network expert panel recommendations on management of neuroendocrine neoplasms (NENs) stomach and duodenum, including gastrinoma. The discuss epidemiology, pathogenesis clinical presentation these tumours as well their diagnosis, biochemical, histopathological localisation diagnosis. principles treatment are discussed, endoscopic, surgical, pharmacological radionuclide treatment. Finally, patient monitoring given. (Endokrynol Pol...

10.5603/ep.2013.0030 article EN Endokrynologia Polska 2014-01-03
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