A5061894599- Gastric Cancer Management and Outcomes
- Helicobacter pylori-related gastroenterology studies
- Neuroendocrine Tumor Research Advances
- Pancreatic and Hepatic Oncology Research
- Genetic factors in colorectal cancer
- Lung Cancer Research Studies
- Metastasis and carcinoma case studies
- Gastrointestinal disorders and treatments
- Inflammatory Bowel Disease
- Digestive system and related health
- Cancer Cells and Metastasis
- Gastrointestinal Tumor Research and Treatment
- Colorectal Cancer Screening and Detection
- Cancer Research and Treatments
- Cancer-related Molecular Pathways
- BRCA gene mutations in cancer
- Pancreatitis Pathology and Treatment
- Lung Cancer Treatments and Mutations
- Eosinophilic Esophagitis
- Diverticular Disease and Complications
- Liver Disease Diagnosis and Treatment
- Mesenchymal stem cell research
- Liver Disease and Transplantation
- Neuroblastoma Research and Treatments
- Ovarian cancer diagnosis and treatment
Pomeranian Medical University
2016-2025
Jagiellonian University
2022
University of Szczecin
2016
Medical University of Warsaw
2015
Children's Memorial Health Institute
2014
Medical University of Silesia
2014
University Gastroenterology
2014
Szczecin Academy of Arts
2001-2003
Ministry of Health
2000
Cancer Registry of Norway
2000
W ostatnim czasie obserwuje się większe zainteresowanie rzadkimi nowotworami neuroendokrynnymi żołądkowo-jelitowo-trzustkowymi (GEP NEN). Wykrywalność nowotworów neuroendokrynnych w ostatnich latach wzrosła. Ponad 50% GEP NEN stanowią rakowiaki, które najczęściej są znajdowane przypadkowo podczas zabiegu operacyjnego jelicie cienkim i wyrostku robaczkowym oraz momencie rozpoznania przerzutów odległych, głównie do wątroby. Istnieje konieczność współdziałania specjalistów różnych dziedzin...
Continuous progress in the diagnostics and treatment of neuroendocrine neoplasms (NENs), emerging results new clinical trials, guidelines issued by medical societies have prompted experts from Polish Network Neuroendocrine Tumours to update 2017 recommendations regarding management neoplasms. This article presents general for NENs, resulting findings participating Fourth Round Table Conference, entitled "Polish Guidelines Diagnostics Treatment Neoplasms gastrointestinal tract, Żelechów, June...
Developmentally early cells, including hematopoietic stem progenitor cells (HSPCs), mesenchymal (MSCs), endothelial (EPCs), and very small embryonic-like (VSELs), are mobilized into peripheral blood (PB) in response to tissue/organ injury. We sought determine whether these PB patients with Crohn's disease (CD).Twenty-five active CD, 20 clinical remission, 25 age-matched controls were recruited samples harvested. The circulating CD133+/Lin-/CD45+ CD34+/Lin-/CD45+ enriched for HSPCs,...
Abstract Various experimental studies indicate potential involvement of bone marrow ( BM )‐derived stem cells SC s) in malignancy development and progression. In this study, we comprehensively analysed systemic trafficking various populations BM‐derived SCs BMSC s), i.e ., mesenchymal, haematopoietic, endothelial stem/progenitor MSC s, HSC EPC s respectively), recently discovered population very small embryonic/epiblast‐like VSEL pancreatic cancer patients. Circulating CD 133 + /Lin − / 45...
Background/Aims Recent experimental studies have suggested that various cytokines may be important players in the development and progression of pancreatic cancer. However, these findings not yet been verified a clinical setting. Methods In this study, we examined levels broad panel cytokines, including interleukin (IL)-1, IL-6, IL-8, IL-10, IL-12, IL-17, IL-23, as well tumor necrosis factor alpha (TNFα) granulocyte-colony stimulating (G-CSF) patients with adenocarcinoma (n = 43), other...
Accumulating evidence indicates the potential effect of microbiota on pathogenesis and course schizophrenia. However, effects olanzapine, second-generation antipsychotics, gut have not been investigated in humans. This study aimed to analyze fecal schizophrenia patients treated with olanzapine during six weeks their hospital stay. After a seven-day washout from all psychotropic medications, compositions were evaluated at baseline after hospitalization using 16S rRNA sequencing. The was...
Progress in the diagnostics and therapy of gastro-entero-pancreatic (GEP) neuroendocrine neoplasms (NEN), published results new randomised clinical trials, guidelines issued by European Neuroendocrine Tumour Society (ENETS) have led Polish Network Tumours to update 2013 regarding management these neoplasms. We present general recommendations for NENs, developed experts during Third Round Table Conference - Diagnostics neoplasms: view current recommenda-tions, which took place December 2016...
5T4 oncofetal antigen is defined by a monoclonal antibody raised against human placental trophoblast, and recognizes 72 kD glycoprotein expressed in many different carcinomas but detected only at low levels some normal epithelia. Analysis of the patterns expression colorectal has indicated significant association between presence tumor cells metastatic spread. The epithelial ovarian been investigated immunohistochemistry; 71% demonstrated positive immunoreactivity adenocarcinoma and/or...
The complement cascade seems to be an important mediator modulating renal ischemia/reperfusion injury. This study analyzed whether significant changes occur in the levels of a terminal panel molecules (C3a, C5a, and C5b-9/membrane attack complex) during early phase human kidney allograft reperfusion evaluated potential association these with clinical post-transplant graft function transplant recipients.Seventy-five recipients undergoing transplantation between 2004 2006 were enrolled divided...
Most inflammatory bowel diseases (IBDs) are classic complex disorders represented by common alleles. Here we aimed to define the genetic architecture of pediatric and adult-onset IBDs for Polish population. A total 1495 patients were recruited, including 761 with Crohn's disease (CD; 424 pediatric), 734 ulcerative colitis (UC; 390 934 healthy controls. Allelotyping employed a pooled-DNA genome-wide association study (GWAS) was validated individual genotyping. Whole exome sequencing (WES)...
<i>Objective:</i> The aim of this study was to evaluate the efficacy adjuvant chemotherapy with etoposide, Adriamycin and cisplatin (EAP) after potentially curative resections for gastric cancer. <i>Methods:</i> After surgery, patients were randomly assigned EAP or control arm. Chemotherapy included 3 courses, administered every 28 days. Each cycle consisted doxorubicin (20 mg/m<sup>2</sup>) on days 1 7, (40 2 8, etoposide (120 4, 5, 6....
Endoscopic submucosal dissection (ESD) has a high curative resection rate for gastrointestinal mucosal lesions, but is not used widely in Europe because of complication and long learning curve. This study analyzed the ESD curve at single European treatment center.ESD hybrid-ESD (hESD) procedures were to treat large colonic lesions that could be resected one piece by other endoscopic methods. Procedure duration speed, en-bloc, complete (R0) resection, rates analyzed.Fifty-three patients...
Polish recommendations regarding management of patients suffering from neuroendocrine tumors small intestine and appendix are presented. Small intestine, especially ileum represent most common origin these tumors. Majority them well differentiated grow slowly. Rarely, they less with fast growth poor prognosis. Symptoms atypical, diagnosis could be often accidental. In 4-10% typical symptoms carcinoid syndrome present. Chromogranin A is useful in the laboratory diagnostics, urinary excretion...