Janusz Strzelczyk
A5103176786- Neuroendocrine Tumor Research Advances
- Lung Cancer Research Studies
- Pituitary Gland Disorders and Treatments
- Pancreatic and Hepatic Oncology Research
- Neuroblastoma Research and Treatments
- Thyroid Disorders and Treatments
- Vector-borne infectious diseases
- Peptidase Inhibition and Analysis
- Growth Hormone and Insulin-like Growth Factors
- Regulation of Appetite and Obesity
- Viral-associated cancers and disorders
- Ophthalmology and Eye Disorders
- Head and Neck Cancer Studies
- Hedgehog Signaling Pathway Studies
- Bone health and treatments
- Helicobacter pylori-related gastroenterology studies
- TGF-β signaling in diseases
- Adrenal and Paraganglionic Tumors
- Digestive system and related health
- Vector-Borne Animal Diseases
- Delphi Technique in Research
- Metastasis and carcinoma case studies
- Powdery Mildew Fungal Diseases
- Cancer-related molecular mechanisms research
- Cerebrovascular and genetic disorders
Medical University of Silesia
2013-2024
Medical University of Lodz
2023
University of Colorado Health
2005
W ostatnim czasie obserwuje się większe zainteresowanie rzadkimi nowotworami neuroendokrynnymi żołądkowo-jelitowo-trzustkowymi (GEP NEN). Wykrywalność nowotworów neuroendokrynnych w ostatnich latach wzrosła. Ponad 50% GEP NEN stanowią rakowiaki, które najczęściej są znajdowane przypadkowo podczas zabiegu operacyjnego jelicie cienkim i wyrostku robaczkowym oraz momencie rozpoznania przerzutów odległych, głównie do wątroby. Istnieje konieczność współdziałania specjalistów różnych dziedzin...
Continuous progress in the diagnostics and treatment of neuroendocrine neoplasms (NENs), emerging results new clinical trials, guidelines issued by medical societies have prompted experts from Polish Network Neuroendocrine Tumours to update 2017 recommendations regarding management neoplasms. This article presents general for NENs, resulting findings participating Fourth Round Table Conference, entitled "Polish Guidelines Diagnostics Treatment Neoplasms gastrointestinal tract, Żelechów, June...
Progress in the diagnostics and therapy of gastro-entero-pancreatic (GEP) neuroendocrine neoplasms (NEN), published results new randomised clinical trials, guidelines issued by European Neuroendocrine Tumour Society (ENETS) have led Polish Network Tumours to update 2013 regarding management these neoplasms. We present general recommendations for NENs, developed experts during Third Round Table Conference - Diagnostics neoplasms: view current recommenda-tions, which took place December 2016...
Polish recommendations regarding management of patients suffering from neuroendocrine tumors small intestine and appendix are presented. Small intestine, especially ileum represent most common origin these tumors. Majority them well differentiated grow slowly. Rarely, they less with fast growth poor prognosis. Symptoms atypical, diagnosis could be often accidental. In 4-10% typical symptoms carcinoid syndrome present. Chromogranin A is useful in the laboratory diagnostics, urinary excretion...
In this paper, we present the current guidelines for diagnostics and management of pancreatic neuroendocrine neoplasms (PanNENs) developed by Polish experts providing care these patients in everyday clinical practice. oncological diagnostics, addition to biochemical tests, molecular identification with use NETest liquid biopsy circulating microRNAs is gaining importance. Both anatomical functional examinations (including new radiopharmaceuticals) are used imaging diagnostics....
Neuroendocrine neoplasms/tumours (NENs/NETs) of the large intestine are detected increasingly often, especially rectal tumours, which is probably associated with widespread use screening colonoscopy. There a growing body evidence supporting thesis that NENs rectum and colon two different diseases. Rectal usually small lesions, low to moderate histological malignancy, good prognosis, most may be treated endoscopically. colon, however, often aggressive, poorly differentiated, poor or...
Updated Polish recommendations for the management of patients with neuroendocrine neoplasms (NENs) small intestine (SINENs) and appendix (ANENs) are presented here. The intestine, especially ileum, is one most common locations these neoplasms. Most them well-differentiated slow-growing tumours; uncommonly - carcinomas. Their symptoms may be untypical their diagnosis delayed or accidental. Najczęściej pierwszą manifestacją ANEN jest jego ostre zapalenie. Typical carcinoid syndrome occur in...
Nowotwory neuroendokrynne (NENs) jelita grubego stanowią 20% wszystkich nowotworów neuroendokrynnych. Najczęstszą ich lokalizacją jest odbytnica. są wykrywane coraz częściej i liczba ta będzie wzrastać z uwagi na powszechność wykonywania kolonoskopii, w tym badań przesiewowych oraz usuwanie wykrytych zmian. W pracy przedstawiono aktualne zalecenia dotyczące diagnostyki terapii NEN grubego, uwzględnieniem biochemicznej, patomorfologicznej, nowych technik obrazowania leczenia endoskopowego,...
Recent studies identified viral and bacterial factors, including HSV-1 H. pylori, as possible factors associated with diseases such chronic tonsillitis cancers, head neck squamous cell carcinoma (HNSCC). We assessed the prevalence of HSV-1/2 pylori in patients HNSCC, tonsillitis, healthy individuals using PCR after DNA isolation. Associations were sought between presence HSV-1, clinicopathological demographic characteristics stimulant use. most frequently controls (HSV-1: 12.5% pylori:...
Neuroendocrine tumors are a heterogeneous group of located mainly in the gastrointestinal tract or respiratory system. We aimed to determine concentrations IGF-1R, ERK2, and EGFR using ELISA method serum samples from patients with NETs control group. Results were evaluated selected demographic, clinicopathological, biochemical characteristics. The analyses performed on (80 study 62 group) showed that concentration neuroendocrine was significantly higher (p < 0.001) compared Additionally,...
Neuroendocrine tumors (NETs) are a heterogeneous group of that characteristically different from other malignancies. The difference is not only in the prognosis, which usually more favorable such patients, but also high clinical progression disease, where NET patients do experience cachexia typical purposes this study were to evaluate ghrelin and leptin levels diagnosed with gastroenteropancreatic neuroendocrine (GEP-NETs) bronchopulmonary (BP-NETs) analyze relationship between body mass...
Thyroid diseases, which may occur as focal or diffuse changes in thyroid parenchyma, are most often observed women.Our aim was to assess the prevalence of incidental uptake 68Ga-DOTATATE PET/CT patients referred Nuclear Medicine Department for evaluation neuroendocrine neoplasia (NEN).We retrospectively evaluated 1150 images. Clinical history, serum TSH and antibody (TAb) concentrations, ultrasonography, cytological assessment material from fine-needle aspiration biopsy (FNA) lesion were...
Epstein-Barr virus (EBV) is a common worldwide that an etiologic agent in the development of many diseases, including cancer. Recent reports have shown association EBV with tumorigenesis head and neck squamous cell carcinoma (HNSCC). Moreover, has been reported to be present tonsillar tissues, which suggests close relationship between viral infections chronic tonsillitis. The aim study was analyze prevalence DNA 86 patients HNSCC, 70 tonsillitis, 144 healthy individuals (control group)...
Human papillomavirus (HPV) is a virus with the potential to infect human epithelial cells and an etiological agent of many types cancer, including head neck cancer. The aim study was determine prevalence HPV infection in patients squamous cell carcinoma (HNSCC), chronic tonsillitis, healthy individuals, establish high- low-risk genotypes these groups. objectives also comprised delineation relationship between or subtypes clinicopathological demographic characteristics This composed 76...
To assess resource utilization and costs of treatment with lanreotide AUTOGEL 120 mg (ATG120) administered as part routine acromegaly care in Poland.A multicentre, non-interventional, observational study on Polish acromegalic patients treated ATG120 at 4 weeks or extended (> weeks) dosing interval. The recruited adult medically for ≥ 1 year including least 3 injections ATG120. Data interval, aspects administration, were collected prospectively during 12 months. Costs calculated PLN from the...
After another meeting of experts the Polish Network Neuroendocrine Tumours, updated recommendations for management patients with gastric and duodenal neuroendocrine neoplasms, including gastrinoma, have been issued. As before, epidemiology, pathogenesis clinical symptoms these neoplasms discussed, as well principles diagnostic procedures, biochemical histopathological diagnostics tumour localisation, highlighting changes introduced in recommendations. Updated therapeutic also presented,...
Colorectal neuroendocrine neoplasm (CRNEN), especially rectal tumours, are diagnosed with increased frequency due to the widespread use of colonoscopy, including screening examinations. It is important constantly update and promote principles optimal diagnostics treatment these neoplasms. Based on latest literature arrangements made at working meeting Polish Network Neuroendocrine Tumours (June 2021), this paper includes updated supplemented data guidelines for management CRNEN originally...