- Steroid Chemistry and Biochemistry
- Microbial Metabolic Engineering and Bioproduction
- Pharmacogenetics and Drug Metabolism
- Electrochemical sensors and biosensors
- Enzyme Catalysis and Immobilization
- Biochemical Analysis and Sensing Techniques
- Analytical Chemistry and Chromatography
- Enzyme Structure and Function
- Carbon dioxide utilization in catalysis
- Plant Molecular Biology Research
- Electrospun Nanofibers in Biomedical Applications
- Plant Gene Expression Analysis
- biodegradable polymer synthesis and properties
Jerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences
2019-2024
Jagiellonian University
2019-2020
3-Ketosteroid Δ
The inherent brittleness of polyhydroxybutyrate (PHB), a well-studied polyhydroxyalkanoate (PHA), limits its applicability in flexible and impact-resistant applications. This study explores the potential blending PHB with different PHA to overcome brittleness. synthesis polymers, including an amorphous medium-chain-length (aPHA) consisting various monomers, was achieved previous works through canola oil fermentation. Detailed characterization aPHA revealed nature, as well good thermal...
3-Ketosteroid Δ1-dehydrogenases (KstD) are important microbial flavin enzymes that initiate the metabolism of steroid ring A and useful find application in synthesis drugs. We present a structure KstD from Sterolibacterium denitrificans (AcmB), which contains previously uncharacterized membrane-associated domain extended proton-relay system. The experimental theoretical studies show 1,2-dehydrogenation proceeds according to Ping-Pong bi-bi kinetics two-step base-assisted elimination (E2cB)...
3-Ketosteroid Δ1-dehydrogenases (KstD) are important microbial flavin enzymes that initiate the metabolism of steroid ring A and find application in synthesis drugs. We present a structure KstD from Sterolibacterium denitrificans (AcmB), which contains previously uncharacterized putative membrane-associated domain extended proton-relay system. The experimental theoretical studies show 1-dehydrogenation proceeds according to Ping-Pong bi-bi kinetics two-step base-assisted elimination (E2cB)...