Olga Zastawny

ORCID: 0000-0002-1936-3157
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About
Contact & Profiles
Research Areas
  • Steroid Chemistry and Biochemistry
  • Microbial Metabolic Engineering and Bioproduction
  • Pharmacogenetics and Drug Metabolism
  • Electrochemical sensors and biosensors
  • Enzyme Catalysis and Immobilization
  • Biochemical Analysis and Sensing Techniques
  • Analytical Chemistry and Chromatography
  • Enzyme Structure and Function
  • Carbon dioxide utilization in catalysis
  • Plant Molecular Biology Research
  • Electrospun Nanofibers in Biomedical Applications
  • Plant Gene Expression Analysis
  • biodegradable polymer synthesis and properties

Jerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences
2019-2024

Jagiellonian University
2019-2020

The inherent brittleness of polyhydroxybutyrate (PHB), a well-studied polyhydroxyalkanoate (PHA), limits its applicability in flexible and impact-resistant applications. This study explores the potential blending PHB with different PHA to overcome brittleness. synthesis polymers, including an amorphous medium-chain-length (aPHA) consisting various monomers, was achieved previous works through canola oil fermentation. Detailed characterization aPHA revealed nature, as well good thermal...

10.3390/ma17133105 article EN Materials 2024-06-25

3-Ketosteroid Δ1-dehydrogenases (KstD) are important microbial flavin enzymes that initiate the metabolism of steroid ring A and useful find application in synthesis drugs. We present a structure KstD from Sterolibacterium denitrificans (AcmB), which contains previously uncharacterized membrane-associated domain extended proton-relay system. The experimental theoretical studies show 1,2-dehydrogenation proceeds according to Ping-Pong bi-bi kinetics two-step base-assisted elimination (E2cB)...

10.26434/chemrxiv-2022-b4tsf preprint EN cc-by 2022-09-28

3-Ketosteroid Δ1-dehydrogenases (KstD) are important microbial flavin enzymes that initiate the metabolism of steroid ring A and find application in synthesis drugs. We present a structure KstD from Sterolibacterium denitrificans (AcmB), which contains previously uncharacterized putative membrane-associated domain extended proton-relay system. The experimental theoretical studies show 1-dehydrogenation proceeds according to Ping-Pong bi-bi kinetics two-step base-assisted elimination (E2cB)...

10.26434/chemrxiv-2022-b4tsf-v2 preprint EN cc-by 2022-12-12
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