A5056752645- Enzyme Catalysis and Immobilization
- Microbial Metabolic Engineering and Bioproduction
- Enzyme Production and Characterization
- Amino Acid Enzymes and Metabolism
- Chemical Reactions and Isotopes
- Protein Hydrolysis and Bioactive Peptides
- Cassava research and cyanide
- Enzyme Structure and Function
- Biofuel production and bioconversion
- Microbial Metabolism and Applications
- Electrochemical sensors and biosensors
- Carbohydrate Chemistry and Synthesis
- Fungal Biology and Applications
- Chemical Synthesis and Analysis
- Microbial Natural Products and Biosynthesis
- Enzyme-mediated dye degradation
- Enzyme function and inhibition
- Glycosylation and Glycoproteins Research
- Nanomaterials for catalytic reactions
- Microbial bioremediation and biosurfactants
- melanin and skin pigmentation
- Pesticide and Herbicide Environmental Studies
- Advanced oxidation water treatment
- Chromium effects and bioremediation
- Innovative Microfluidic and Catalytic Techniques Innovation
Czech Academy of Sciences
2015-2025
Czech Academy of Sciences, Institute of Microbiology
2015-2025
Česká Zbrojovka (Czechia)
2015
Institute of Microbiology
2013-2014
Czech Academy of Sciences, Institute of Physics
2003
Charles University
2003
Biogen (United States)
1995
The use of nitrile hydratases (RCN + H2O → RCONH2) and nitrilases 2 RCOO- NH4 +) in biocatalysis attracts profound attention from the beginning 1980s since it provides a useful alternative to conventional hydrolysis using strong acid or base catalysts. In past 5 years potential this branch biotransformations has been broadened significantly by both isolation new mesophilic thermophilic nitrile-metabolizing microorganisms purification nitrile-converting enzymes, including thermostable ones....
The biological activity of the pigment extracts from Monascus purpureus included their antibiotic action not only against bacteria but also some species yeasts and filamentous fungi, as well embryotoxicity teratogenicity. These activities depended on presence orange component (monascorubrin rubropunctatin). formation these compounds was influenced by composition culture medium cultivation fungus: when amino acids, peptides or proteins were available during cultivation, in case solid‐state...
Rubropunctatin (1), monascorubrin (2), monascin (3) and ankaflavin (4) were purified from the mycelium of Monascus purpureus by flash chromatography on silica gel or reversed phase. Their embryotoxicity towards chicken embryos decreased in order 2 > 1 3 4. The lower homologues exhibited teratogenic effects these organisms. Significant antibiotic activities against Bacillus subtilis Candida pseudotropicalis found with compounds 2. Immunosuppressive activity mouse T-splenocytes was most...
AbstractBiotransformations using microbial nitrile- and amide-converting enzymes have developed considerably in the recent years. Most processes profited from stereo-, regio- chemoselectivity of nitrile hydratases, nitrilases amidases specific for primary or secondary amides. The aim this review is to discuss developments branch biotransformations last ca. 5 years by taking highlights research journals, patents industrial applications.KeywordsNitrile...
The cyanide-containing effluents originate from, e.g., mining, coking, electroplating and chemical syntheses. form concentration of cyanide, the effluent matrix depend on source. Electroplating contain extreme amounts free cyanide (fCN), >50 g/L, along with metal complexes. "Raw coking effluents", i.e. coke oven after tar ammonia separation, up to over 100 mg total (TCN)/L, a significant part which is fCN. They are also contaminated phenols, other organic compounds, inorganic salts....