Sleep disorders and psychological disturbances are common in end-stage renal disease (ESRD) patients. However, despite their frequency importance, such conditions often go unnoticed, since all patients do not clearly manifest fully expressed symptoms.This study aimed to determine the prevalence of depression poor sleep quality examine association between these demographic, clinical treatment-related characteristics ESRD on hemodialysis (HD).The included 222 (132 men 90 women), mean age 57.3...

Objectives: Headache is among most frequently encountered neurological symptom during hemodialysis (HD), but still under investigated in peritoneal dialysis (PD) patients. The aim of this study was to assess the incidence and clinical characteristics headache (DH) HD PD Material methods: A total 409 patients (91 on 318 HD) were interviewed using a structured questionnaire, designed according diagnostic criteria International Classification Disorders from 2004. Patients with DH underwent...

Small intestine mucosa is often affected with malabsorptive, autoimmune and inflammatory pathological processes. However, morphometric data on the healthy human small mucosa, especially ileum, are scarce. We aimed to obtain histoquantitative jejunal ileal assess effects of gender ageing these parameters. Computer-aided analysis was performed 24 25 biopsy samples collected upon routine endoscopy screening persons a family history intestinal malignancy. Subjects were distributed in four groups...

Objective This study was conducted to assess the possible weekend effect in patients with upper gastrointestinal bleeding (UGIB) on basis of a 10-year single-center experience Serbia. Materials and methods A retrospective analysis hospital records University Clinic 'Dr Dragisa Misovic-Dedinje', Belgrade, Serbia, from 2002 2012 conducted. Patients admitted for UGIB were identified, data demographic characteristics, symptoms, drug use, alcohol abuse, diagnosis treatment collected. Univariate...

The aim of this study was to evaluate and analyze the incidence features headaches in patients undergoing hemodialysis.In prospective 318 patients, 119 women 199 men, chronic HD four hemodialysis centers Serbia, were questioned about their problems with using a questionary designed according diagnostic criteria International Headache Classification Disorders (ICHD) from 2004. Patients distributed two groups presence (HDH). compared regarding sex, age, duration HD, primary diseases that lead...

The aim of this study was to determine the levels cystatin C, creatinine and clearance in different trimesters uncomplicated pregnancy women with normal kidney function.A total 109 pregnant were included: group 1 - 38 (average age 29.63 ± 4.3 y) first trimester, Group 2 32 33.56 5.95 second trimester 3 39 30.1 6.95 third trimester. Serum C determined by PENIA method (Particle-Enhanced Nephelometric Immuno-Assay), using Behring tests (Behring Diagnostics GmbH, Marburg, Germany). Results...

Cardiovascular Mortality in Hemodialysis Patients: Clinical and Epidemiological Analysis diseases are the leading cause of death hemodialysis (HD) patients. The annual cardiovascular mortality rate these patients is 9%, with left ventricular (LV) hypertrophy, ischemic heart disease failure being most prevalent causes death. aim this study was to determine estimate influence risk factors on HD A total 115 undergoing for at least 6 months were investigated. Initially a cross-sectional...

Coffee drinking is the main source of caffeine intake among adult population in western world. It has been reported that low to moderate beneficial effect on alertness and cognitive functions healthy subjects. The aim this study evaluate impact habitual coffee consumption function hemodialysis patients.In a cross-sectional study, 86 patients from single-dialysis centre underwent assessment by Montreal Cognitive Assessment tool evaluation for symptoms fatigue, mood, sleep disorders...

Abstract Background and Aims Pentraxin-3 (PTX3), a novel inflammatory biomarker, has been recognized as predictor of cardiovascular events in the general population, including coronary artery disease (CAD). Although PTX3 is elevated dialysis patients, its potential diagnostic value for estimation CAD severity still insufficiently studied. The aim this study was to evaluate association between hemodialysis patients. Method This cross-sectional included 60 angina-free chronic patients (60%...

Background/Aim. Injury-induced anergy is one of the key factors contributing to trauma victims' high susceptibility sepsis. This group patients mostly young age and it therefore essential be able predict as accurately possible development septic complications, so appropriate treatment could provided. The aim this study was assess kinetics interleukin (IL) -6 -10, phospholipase A2- II C-reactive protein (CRP) in severely traumatized explore possibilities for early detection potentially...

Abstract Maintenance hemodialysis (HD) patients often experience fluctuations of volume status. Although hypervolemia possibly induces systemic inflammation, the relationship between status and leptin has not yet been well defined. The aims this study were to determine levels leptin, C‐reactive protein (CRP), ferritin in relation assess inflammatory chronic HD patients. This prospective included 93 divided, based on evaluation using body composition monitor, into normovolemic hypervolemic...

Hyperphosphatemia - The Risk Factor for Adverse Outcome in Maintenance Hemodialysis Patients is a potent stimulator of vascular and valvular calcifications hemodialysis patients. To determine the prevalence hyperphosphatemia assess its effect on outcome patients, total 115 chronic patients were studied. Laboratory parameters determined at baseline, after 12 24 months follow-up. Valvular calcification was assessed with echocardiography. statistically analyzed ANOVA. Survival analysis...

Objective The aim of the present study was to evaluate impact continuous ambulatory peritoneal dialysis (CAPD) on lifestyle elderly patients. Patients and Methods Aspects health-related quality life (QL) were studied in 48 patients (16 men, 32 women) end-stage chronic renal failure (ESRF) undergoing CAPD at Clinic Nephrology, Clinical Centre Serbia. first group comprised 20 adult (8 12 women; age range: 35 – 59 years). second consisted 28 older 65 75 Mean length treatment 5.2 years 3.67...

Peritoneal dialysis (PD) is a well established method of depuration in uremic patients. Standard solutions currently use are not biocompatible with the peritoneal membrane. Studying effects dialysate on membrane humans still challenge. There no consensus ideal experimental model so far. We, therefore, wanted to develop new non-uremic rabbit dialysis, which would be practical, easy conduct, too costly, and convenient investigate long-term effect fluids. The study was done 17 healthy...

The aim of this study was to compare different calculation methods determine lipophilicity, expressed as logP value, seven ACE inhibitors (enalapril, quinapril, fosinopril, lisinopril, cilazapril, ramipril, and benazapril) with significantly structure. Experimentally determined n-octanol/water partition coefficients, logPO/W values, were obtained from relevant literature. correlations between all collected values studied the best agreements calculated experimentally observed for KOWWINlogP...

Vascular endothelial growth factor (VEGF) is a glycoprotein which exerts mitogenic effects on endo thelial cells, enhances neoangiogenesis and microvascular permeability, influences leukocyte kinetics when upreg ulated by hypoxia high-glucose concentration in experimental conditions human pathology. Peritoneal synthesis of VEGF has been demonstrated patients peritoneal dialysis (PD) treated with glucose-based dialy sate solutions.The aim the study was to determine serum effluent...

The specific tool for cardiovascular risk assessment in hemodialysis population has not yet been proposed, despite high prevalence of morbidity, and mortality clinically asymptomatic patients. Coronary artery calcium score (CACS), as a reliable predictor future events, might be valuable approach. We sought to evaluate coronary calcification burden its association with clinical laboratory parameters patients who recently initiated hemodialysis. cross-sectional study included 60 receiving...

In the present study, we investigated relationships between several molecular properties and bioavailability data for seven of most commonly prescribed angiotensin II receptor antagonists (also known as blockers (ARBs) or sartans), candesartan, eprosartan, irbesartan, losartan, olmesartan, telmisartan valsartan. The descriptors ARBs are:, aqueous solubility (logS values), polar surface area (PSA), weight (Mw), volume value (Vol), lipophilicity (logP values) acidity descriptor (pKa1)....

Abstract Background and Aims Patients on maintenance hemodialysis (HD) might be particularly vulnerable to severe COVID-19 due their older age numerous comorbidities. Furthermore, specific treatment regimen substantially exposes them the risk of infection. The abrupt onset novel coronavirus disease (COVID-19) pandemic required prompt action immediate reorganization healthcare services while maintaining necessary standard for chronic patients. In this study, we aimed analyze clinical features...

Protein-energy malnutrition and inflammation are among the leading causes of poor outcome in hemodialysis patients. Hepatitis C virus (HCV) infection is accompanied by elevated proinflammatory mediators, also found dialysis patients with malnutrition-inflammation complex syndrome. We aimed to study rate characteristics syndrome (MICS) patients, especially those hepatitis C. The included 147 (mean age 55.1 +/- 12.9 years), 24.5% whom were HCV-positive, undergoing adequate three times a week...

Background/Aim. Hemodialysis (HD) is a therapeutic procedure used to partially correct homeostatic disorders and prevent complications of uremia appear in the terminal stage renal insufficiency. The aim this study was evaluate analyze incidence features headaches patients undergoing hemodialysis. Methods. A total 143 patients, 50 women 93 men, hemodialysis, were questioned about their problems with headache using questionnaire designed according diagnostic criteria International Headache...