A5017182821- TGF-β signaling in diseases
- Bone health and osteoporosis research
- Bone Metabolism and Diseases
- Kidney Stones and Urolithiasis Treatments
- Osteoarthritis Treatment and Mechanisms
- Spine and Intervertebral Disc Pathology
- Bone health and treatments
- Bone Tissue Engineering Materials
- Medical Imaging and Analysis
- Parathyroid Disorders and Treatments
- Bone and Dental Protein Studies
- Pancreatic and Hepatic Oncology Research
- Bone fractures and treatments
- Magnesium in Health and Disease
- Nephrotoxicity and Medicinal Plants
- Orthopaedic implants and arthroplasty
- Bone and Joint Diseases
- Inflammatory Bowel Disease
- Connective Tissue Growth Factor Research
- Genetic factors in colorectal cancer
- Tissue Engineering and Regenerative Medicine
- Muscle Physiology and Disorders
- Hip disorders and treatments
- Therapeutic Uses of Natural Elements
- Heterotopic Ossification and Related Conditions
Stanford University
2024-2025
Opća Bolnica Zadar
2025
University of Rijeka
2004-2023
Grade Medical (Czechia)
2023
University of Osijek
2010-2020
Klinički bolnički centar Osijek
2017
Marqués de Valdecilla University Hospital
2012
Affymax (United States)
2012
Althaia
2012
University of Messina
2012
The variations of the common carotid artery, as well external and internal arteries, are described. During anatomic dissection on adult cadavers, we investigated variability appearance 40 arterial systems. Special consideration was given to topographic relations such level bifurcation relationship between origin great collateral branches. attention paid superior thyroid artery. In this article practical importance these is stressed.
Bone- and cartilage-derived morphogenetic proteins (BMPs CDMPs), which are TGFbeta superfamily members, growth differentiation factors that have been recently isolated, cloned biologically characterized. They important regulators of key events in the processes bone formation during embryogenesis, postnatal growth, remodelling regeneration skeleton. In present study, we used immunohistochemical methods to investigate distribution BMP-2, -3, -5, -6, -7 CDMP-1, -2, -3 human osteophytes...
The objective was to evaluate new commercially available ion-releasing restorative materials and compare them established anti-cariogenic materials. Four were tested: alkasite Cention (Ivoclar Vivadent) in self-cure or light-cure mode, giomer Beautifil II (Shofu), conventional glass-ionomer Fuji IX (GC), resin composite Tetric EvoCeram as a control. Flexural strength, flexural modulus, Weibull modulus measured one day, three months, after months with accelerated aging ethanol. Water sorption...
Maternal obesity increases risk for bronchopulmonary dysplasia (BPD) by up to 42%. Identifying metabolic features that may contribute the association between maternal pre-pregnancy body mass index (BMI) and BPD is critical in defining molecular relationship these conditions. We investigated using newborn screen metabolites as an explanatory variable. hypothesized elevated BMI compared a normal referent group, associated with increased circulating short long-chain acylcarnitines subsequent...
While medication intake is common among pregnant women, safety remains underexplored, leading to unclear guidance for patients and healthcare professionals. PregMedNet addresses this gap by providing a multifaceted maternal framework based on systematic analysis of 1.19 million mother-baby dyads from U.S. claims databases. A novel confounding adjustment pipeline was applied systematically control confounders multiple medication-disease pairs, robustly identifying both known effects. Notably,...
Cilj: Prikazati bolesnika s karcinomom pluća kod kojega su metastaze u bubrege dovele do akutnog bubrežnog zatajenja koje je iziskivalo liječenje hemodijalizom. Prikaz slučaja: Bolesnik dobi od 65 godina primljen bolnicu zbog otežanog disanja. Učinjenom obradom verificiran karcinom metastazama jetri, obama bubrezima, pleuri te intratorakalnim i intraabdominalnim limfnim čvorovima. U laboratorijskim nalazima bilježi se normocitna anemija uz povišene vrijednosti ureee kreatinina prije...
Abstract Background Congenital and acquired heart disease affects ∼1% of children globally, with right ventricular (RV) dysfunction being a common complex issue due to conditions like congenital (CHD), pulmonary hypertension (PH), prematurity. Accurate RV assessment is challenging its unique geometry, interventricular interactions, morphological variability in pediatric patients. Fractional area change (FAC), key echocardiographic measure, correlates strongly severity, aiding timely...
Bone morphogenetic protein-7 (BMP-7) is a growth and differentiation factor belongs to the TGF-beta superfamily of proteins. Previous studies have shown an abundant expression BMP-7 in developing intestine association with perturbed BMP/SMAD downstream signaling leading malignant phenotype inflammation gut. In present study, we evaluated effect systemically administered recombinant human against trinitrobenzenesulfonic (TNBS) acid induced inflammatory bowel disease (IBD) rats. The TNBS rats...
Abstract Background Female cosmetic genital surgery is rapidly growing. However, controversy reports raised around these procedures question their indications, motives, and safety. Warning against performing this might unjustly restrict surgical alleviation of symptoms. Objectives Through anonymous research, the authors explored patient characteristics motivation, when women started to think about surgery, effects on psychosocial aspects. Methods Of 125 patients who underwent female at Oslo...
Urolithiasis is characterized by the formation and retention of solid crystals within urinary tract. Kidney stones are mostly composed calcium oxalate, which predominantly generates free radicals that toxic to renal tubular cells. The aim study explore possible effects antioxidant pre-treatment on inhibition oxidative stress. Three cell lines were used as in vitro model urolithiasis: MDCK I, II LLC-PK1. Oxidative stress was induced exposure cells sodium oxalate concentration 8 mM. In order...
Beyond stimulating bone formation, morphogenetic proteins (BMPs) are important in development, inflammation, and malignancy of the gut. We have previously shown that BMP7 has a regenerative, anti-inflammatory, antiproliferative effect on experimental inflammatory bowel disease (IBD) rats. To further investigate BMP signaling pathway we monitored therapy components rat colon during different stages experimentally induced colitis by 2,4,6-trinitrobenzene sulfonic acid (TNBS). The results...
Chronic kidney disease mineral- and bone disorder (CKD-MBD) has been studied more often in dialysis than predialysis CKD patients. The association between efficacy of hyperphosphatemia control chronic renal failure (CRF) progression, prevalence cardiovascular calcification was the objective present investigation.42 patients with Stage 5, regularly monitored for 5 years, were divided into Group 1 20 normal serum phosphate (sPO4) levels 2 22 registered at majority checks. Serum urea,...
The coronary sinus is an anatomic landmark and conduit for many diagnostic therapeutic procedures. We studied 40 human canine sinuses of the heart in order to ascertain various functional features its tributaries. performed a comparative analysis cardiac veins. also formation, tributaries, length, diameter ostium sinus. tributaries were highly variable dog. main constantly present both great middle found rare case small vein connecting two venous systems--the anterior In cases we common...
Background. Diagnostic criteria for Balkan endemic nephropathy (BEN) have not been precisely established. In the present study predictive value of variables previously proposed as diagnostic BEN was examined. Methods. The involved 182 patients: 98 patients with BEN, 57 other kidney diseases (20 glomerulonephritis, 17 tubulointerstitial and 20 hypertensive nephrosclerosis) 27 healthy subjects. group comprised who fulfilled suspected together proteinuria at least two tubular abnormalities or...
Patient satisfaction after rhinoplasty is a growing area of research. The FACE-Q Rhinoplasty Module, used to assess these values, requires translation national languages.Fourteen questions assessing the Satisfaction with Nose Scale and Adverse Effects Checklist Module were translated Norwegian adherence Mapi Research Trust guidelines. Answers processed by QuestBack anonymously. Of 243 patients undergoing at Oslo Plastic Surgery Clinic, 214 reachable e-mail.Response rates pre- postoperative...
The aim of this study was to evaluate and analyze the incidence features headaches in patients undergoing hemodialysis.In prospective 318 patients, 119 women 199 men, chronic HD four hemodialysis centers Serbia, were questioned about their problems with using a questionary designed according diagnostic criteria International Headache Classification Disorders (ICHD) from 2004. Patients distributed two groups presence (HDH). compared regarding sex, age, duration HD, primary diseases that lead...
In Brief Study Design. Histomorphometric evaluation of autopsy material. Objectives. To explore region-dependent changes that occur with aging in trabecular and cortical bone the human vertebral body. Summary Background Data. Human is continuously subjected to external forces (loads) promote inner architecture. This functional adaptability limited, however, when lost, progressively deteriorates becomes subject injury increases mechanical loading. Methods. Bone cylinders were drilled a...