Charitha D. Reddy

ORCID: 0000-0003-0062-1272
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About
Contact & Profiles
Research Areas
  • Congenital Heart Disease Studies
  • Cardiovascular Function and Risk Factors
  • Coronary Artery Anomalies
  • Cardiac Valve Diseases and Treatments
  • Kawasaki Disease and Coronary Complications
  • Cardiac Arrhythmias and Treatments
  • Ultrasound in Clinical Applications
  • Atrial Fibrillation Management and Outcomes
  • Cardiovascular Issues in Pregnancy
  • Ovarian function and disorders
  • Cardiac pacing and defibrillation studies
  • Cardiac Imaging and Diagnostics
  • Reproductive Biology and Fertility
  • Pulmonary Hypertension Research and Treatments
  • Congenital Diaphragmatic Hernia Studies
  • Cardiovascular Syncope and Autonomic Disorders
  • Artificial Intelligence in Healthcare and Education
  • Bacterial Infections and Vaccines
  • Vascular anomalies and interventions
  • Congenital heart defects research
  • Reproductive System and Pregnancy
  • Advanced X-ray and CT Imaging
  • Cardiac electrophysiology and arrhythmias
  • Privacy-Preserving Technologies in Data
  • Biofield Effects and Biophysics

Stanford University
2006-2025

Lucile Packard Children's Hospital
2015-2024

Palo Alto University
2023

University of Utah
2023

Stanford Medicine
2022

Dr. Reddy's Laboratories (United States)
2021

Children's Hospital of Los Angeles
2015

University of California, Irvine
2011

Significant interobserver and interstudy variability occurs for left ventricular (LV) functional indices despite standardization of measurement techniques. Artificial intelligence models trained on adult echocardiograms are not likely to be applicable a pediatric population. We present EchoNet-Peds, video-based deep learning algorithm, which matches human expert performance LV segmentation ejection fraction (EF).

10.1016/j.echo.2023.01.015 article EN other-oa Journal of the American Society of Echocardiography 2023-02-07

Abstract Background Congenital and acquired heart disease affects ∼1% of children globally, with right ventricular (RV) dysfunction being a common complex issue due to conditions like congenital (CHD), pulmonary hypertension (PH), prematurity. Accurate RV assessment is challenging its unique geometry, interventricular interactions, morphological variability in pediatric patients. Fractional area change (FAC), key echocardiographic measure, correlates strongly severity, aiding timely...

10.1101/2025.03.14.25323989 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2025-03-15

Atrioventricular nodal reentrant tachycardia (AVNRT) typically occurs in adolescents and adults with limited data regarding AVNRT young children.All patients who underwent electrophysiology study ablation between 2005 2012 were retrospectively studied. Patients stratified by age <10 years (young AVNRT) or ≥10 (older AVNRT). Young also compared to age-matched orthodromic (ORT).A total of 275 studies 272 evaluated including 38 (7.7 ± 1.5 years) 202 older (14.9 2.1 years). An atrial-His jump...

10.1111/pace.12699 article EN Pacing and Clinical Electrophysiology 2015-07-31

Kawasaki disease (KD) is the leading cause of acquired heart in children. The major challenge KD diagnosis that it shares clinical signs with other childhood febrile control (FC) subjects. We sought to determine if our algorithmic approach applied a Taiwan cohort.A single center (Chang Gung Memorial Hospital Taiwan) cohort patients suspected acute were prospectively enrolled by local specialists for analysis. Our previously single-center developed computer-based two-step algorithm was...

10.3389/fimmu.2022.1031387 article EN cc-by Frontiers in Immunology 2022-10-03

Background Although aortic dilation is common in tetralogy of Fallot (TOF), its progression and risk dissection are not well understood. The mechanism primarily attributed to increased flow utero; an alternative unequal septation the truncus arteriosus resulting a larger aorta inherently hypoplastic pulmonary artery (PA). If latter true, we hypothesize PA ratio TOF stable throughout gestation, sums great dimensions similar controls. Methods Results We performed single-center retrospective...

10.1161/jaha.123.030083 article EN cc-by-nc-nd Journal of the American Heart Association 2023-11-06

Abstract Introduction: Transcatheter pulmonary valve replacement serves as a successful alternative to surgical of right ventricle artery conduit. Guidelines for recommending transcatheter depend on MRI ventricular volumes, which have been correlated the echocardiographic measure annular tilt. We aim assess whether tilt can be clinically useful tool in acute and long-term periods after health. Methods: reviewed 70 patients who underwent at single institution. Echocardiographic measurements...

10.1017/s1047951123001452 article EN cc-by Cardiology in the Young 2023-06-13

Introduction: Echocardiographic assessment of left ventricular (LV) systolic function by ejection fraction (EF) is crucial for diagnosis and monitoring in pediatric patients. EF requires manual tracing the LV but measurement reproducibility affected diverse phenotypes, image quality, operator skill. We sought to train a deep learning model (EchoNet-Peds) on pediatric-specific video dataset automatically segment estimate 5/6 Area Length (AL) using two common views, apical 4 chamber (A4C)...

10.1161/circ.144.suppl_1.10345 article EN Circulation 2021-11-16

Intraoperative imaging determines the integrity of surgical repairs. Transoesophageal echocardiography represents standard care for intraoperative in CHD. However, some conditions preclude its use, and epicardial is used alternatively. Minimal literature exists on impact versus transoesophageal echocardiography. We aimed to evaluate accuracy between two modalities hypothesised higher error rates echocardiography.We retrospectively reviewed all echocardiograms performed over 16 years compared...

10.1017/s1047951122001536 article EN Cardiology in the Young 2022-06-24

ABSTRACT Background Aortic dilation in tetralogy of Fallot (TOF) is primarily attributed to increased aortic flow utero . An alternative hypothesis abnormal neural crest cell migration, with unequal septation the truncus arteriosus resulting a larger aorta and inherently hypoplastic pulmonary artery (PA). If so, we hypothesize PA ratio (Ao:PA) TOF stable throughout gestation, total sum dimensions great arteries similar controls. Methods We performed single-center retrospective study all...

10.1101/2023.03.07.23286960 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2023-03-08

Anomalous coronary artery origin is rare and can occur with myocardial bridging. We describe a 28-year-old patient symptomatic anomalous right arising from the left sinus of Valsalva concomitant bridging anterior descending artery. It was discovered that ran along free ventricular wall trabeculated myocardium composing bridge. To address this, trabecular sinuses were unroofed, resulting edge sutured back to interventricular septum.

10.1016/j.atssr.2023.07.011 article EN cc-by-nc-nd Annals of Thoracic Surgery Short Reports 2023-08-12

Introduction: Neonates with dextro-transposition of the great arteries (d-TGA) require adequate mixing at atrial level. If not present, these infants experience severe cyanosis, necessitating an urgent balloon septostomy (BAS). Multiple studies have identified various fetal echocardiography (FE) findings as risk factors for postnatal BAS. Anecdotally, predictive value remains poor in clinical use. Hypothesis: We aimed to determine relationship between inter-rater reliability (IRR) FE BAS...

10.1161/circ.148.suppl_1.14080 article EN Circulation 2023-11-07

10.1016/j.fertnstert.2006.02.055 article EN publisher-specific-oa Fertility and Sterility 2006-04-01

Abstract Background No guidelines exist for inpatient postoperative transthoracic echocardiographic (TTE) surveillance in congenital heart disease. We prospectively evaluated indications TTEs patients with disease to identify areas improve upon (Phase 1) and then assessed the impact of a simple pilot intervention 2). Methods included RACHS‐1 (Risk Adjustment Congenital Heart Surgery) scores 2 3 keep cohort homogenous. During Phase 1, we collected data which there were no new findings...

10.1111/echo.14505 article EN Echocardiography 2019-10-19

ABSTRACT Kawasaki disease (KD) is the leading cause of acquired heart in children. A key objective research KD to reduce risk long-term cardiovascular sequelae by expediting timely diagnosis. The major challenge diagnosis that it shares clinical signs with other childhood febrile illnesses. Our previously single-center developed computer-based two-step algorithm was further tested a five-center validation US. This first blinded multi-center trial validated our approach, sufficient...

10.1101/2022.05.12.22275028 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2022-05-13
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