A5044742159- Gut microbiota and health
- Neuroendocrine regulation and behavior
- Epigenetics and DNA Methylation
- Pediatric health and respiratory diseases
- Human-Animal Interaction Studies
- Oral microbiology and periodontitis research
- Infant Development and Preterm Care
- Diet and metabolism studies
- Probiotics and Fermented Foods
- Clostridium difficile and Clostridium perfringens research
- Birth, Development, and Health
- Tryptophan and brain disorders
- Gastrointestinal motility and disorders
University of Oxford
2019-2024
University of Helsinki
2023-2024
Abstract Gut microbes shape many aspects of organismal biology, yet how these key bacteria transmit among hosts in natural populations remains poorly understood. Recent work mammals has emphasized either transmission through social contacts or indirect environmental contact, but the relative importance different routes not been directly assessed. Here we used a novel radio-frequency identification-based tracking system to collect long-term high-resolution data on relationships, space use and...
Purpose HELMi (Health and Early Life Microbiota) is a longitudinal, prospective general population birth cohort, set up to identify environmental, lifestyle genetic factors that modify the intestinal microbiota development in first years of life their relation child health well-being. Participants The cohort consists 1055 healthy term infants born 2016–2018 mainly at capital region Finland parents. characterised based on nine, strategically selected, faecal samples connected extensive online...
Abstract Age is a key parameter in population ecology, with myriad of biological processes changing age as organisms develop early life then later senesce. As often hard to accurately measure non‐lethal methods, epigenetic methods estimation (epigenetic clocks) have become popular tool animal ecology and are developed or calibrated using captive animals known age. However, studies typically rely on invasive blood tissue samples, which limit their application more sensitive elusive species....
A curated murine oral microbiome database to be used as a reference for mouse-based studies has been constructed using combination of bacterial culture, 16S rRNA gene amplicon, and whole-genome sequencing. The comprises collection nearly full-length sequences from cultured isolates draft genomes representative taxa collected range sources, including specific-pathogen-free laboratory mice, wild Mus musculusdomesticus formerly wood mouse Apodemus sylvaticus At present, it 103 (MOT) spanning...
Abstract The Saiga are migratory antelopes inhabiting the grasslands of Eurasia. Over last century, have been pushed to brink extinction by mass mortality events and intense poaching. Yet, despite high profile as an animal conservation concern, little is known its biology. In particular, gut microbiota has not studied, potential importance in health. Here, we characterise from two geographically distinct populations Kazakhstan compare it with that other antelope species. We identified a...
Assembly of the mammalian gut microbiota during early life is known to shape key aspects organismal development, including immunity, metabolism and behaviour. While house mice (Mus musculus) are major laboratory model organism for research, their artificial lab-based lifestyle could fundamentally alter ecological processes assembly dynamics, in ways that affect usefulness as a system. To examine this, here we directly compared patterns from lab wild, making use tractable, individually-marked...
Abstract Assembly of the mammalian gut microbiota during early life is known to shape key aspects organismal development, including immunity, metabolism and behaviour. While house mice ( Mus musculus ) are major laboratory model organism for research, their artificial lab-based lifestyle could fundamentally alter ecological processes assembly dynamics, in ways that affect usefulness as a system. To examine this, here we directly compared patterns from lab wild, making use tractable,...
Abstract Age is a key parameter in population ecology, with myriad biological processes changing age as organisms develop early life and later senesce. As often hard to accurately measure non-lethal methods, epigenetic methods of estimation (epigenetic clocks) have become popular tool animal are developed or calibrated using captive animals known age. However, few studies directly compared estimates between wild lab-reared the same species, even though age-related changes can be influenced...