A5078029996- Mosquito-borne diseases and control
- Malaria Research and Control
- Insect Pest Control Strategies
- Viral Infections and Vectors
- Insect and Pesticide Research
- Insect symbiosis and bacterial influences
- Insect Resistance and Genetics
- Vector-borne infectious diseases
- Neurobiology and Insect Physiology Research
- Vector-Borne Animal Diseases
- Entomopathogenic Microorganisms in Pest Control
- Insect Utilization and Effects
- Global Maternal and Child Health
- Insect and Arachnid Ecology and Behavior
- Insect-Plant Interactions and Control
- Child Nutrition and Water Access
- Animal Disease Management and Epidemiology
- Dengue and Mosquito Control Research
- Insect behavior and control techniques
- Olfactory and Sensory Function Studies
- Physiological and biochemical adaptations
- Parasites and Host Interactions
- Advanced Chemical Sensor Technologies
- Species Distribution and Climate Change
- Invertebrate Immune Response Mechanisms
Wageningen University & Research
2015-2024
Ifakara Health Institute
2005-2023
International Centre of Insect Physiology and Ecology
2016-2023
Swiss Tropical and Public Health Institute
2005-2023
National Institute for Public Health and the Environment
2008-2022
Malawi-Liverpool-Wellcome Trust Clinical Research Programme
2020
University of Liverpool
2020
University of Maryland, Baltimore
2020
University of Malawi
2020
University of Girona
2020
Current malaria elimination guidelines are based on the concept that transmission becomes heterogeneous in later phases of [1]. In pre-elimination and phases, interventions have to be targeted entire villages or towns with higher incidence until only individual episodes remain become centre attention With increasing evidence clustering within villages, we argue there is an intermediate step. Heterogeneity present long before areas enter phase, identifying targeting hotspots should form...
Biological control of malaria mosquitoes in Africa has rarely been used vector programs. Recent developments this field show that certain fungi are virulent to adult Anopheles mosquitoes. Practical delivery an entomopathogenic fungus infected and killed gambiae, Africa's main vector, was achieved rural African village houses. An entomological inoculation rate model suggests implementation method, even at the observed moderate coverage during a study Tanzania, would significantly reduce...
Anaplasma phagocytophilum is the etiological agent of granulocytic anaplasmosis in humans and animals. Wild animals ticks play key roles enzootic cycles pathogen. Potential ecotypes A. have been characterized genetically, but their host range, zoonotic potential transmission dynamics has only incompletely resolved. The presence DNA was determined more than 6000 ixodid collected from vegetation wildlife, 289 tissue samples wild domestic animals, 69 keds deer, originating various geographic...
The African malaria mosquito Anopheles gambiae sensu stricto continues to play an important role in transmission, which is aggravated by its high degree of anthropophily, making it among the foremost vectors this disease. In current study we set out unravel strong association between species and human beings, as determined odorant cues derived from skin. Microbial communities on skin key roles production body odour. We demonstrate that composition microbiota affects attractiveness beings...
Immature stages of the malaria mosquito Anopheles gambiae experience high mortality, but its cause is poorly understood. Here we study impact rainfall, one abiotic factors to which immatures are frequently exposed, on their mortality.We show that rainfall significantly affected larval mosquitoes by flushing them out aquatic habitat and killing them. Outdoor experiments under natural conditions in Kenya revealed additional nightly loss larvae caused was average 17.5% for youngest (L1) 4.8%...
The survival, metabolic reserves, and host-seeking response of unfed Anopheles gambiae Giles sensu stricto females different size classes were investigated from 1 to 6 d after emergence. In addition, the effect blood meal frequency feeding on accumulation reserves reproductive development during 1st gonotrophic cycle. Large survived longer contained significantly more protein, glycogen, lipid at emergence than did small females. Over d, large mosquitoes was greater that ones. There no in...
The influence of adult body size on the pre-gravid state and fecundity was studied in Anopheles gambiae Giles females hand-caught inside houses virgin collected as pupae Tanzania. Blood-fed mosquitoes were kept for 2-3 days before dissection examination insemination ovarian condition. Those which did not develop eggs classified pre-gravid. number mature those became gravid counted. Virgin fed egg maturation laboratory. Wing-length measured an index mosquito size. overall rate resting...
Abstract The effects of temperature and larval density on survival larvae, growth rate, age at pupation, adult size (measured as wing length dry weight) laboratory‐reared Anopheles gambiae (Diptera: Culicidae) were studied. Larvae reared three temperatures (24, 27 30 °C) densities (0.5, 1 2 larvae/cm ). strongly interacted to determine the mosquitoes' life‐history parameters. Survival was highest intermediate °C. differences between increased with increasing density. At °C decreased...
Disease transmitting mosquitoes locate humans and other blood hosts by identifying their characteristic odor profiles. Using olfactory organs, the detect compounds present in human breath, sweat skins, use these as cues to obtain from humans. These can be synthesized vitro, then formulated mimic While some synthetic mosquito lures already exist, evidence supporting utility is limited laboratory settings, where long-range stimuli cannot investigated.Here we report development field evaluation...
Ecological and population biology issues constitute serious challenges to the application of genetically modified mosquitos (GMM) for disease control.
The communities of Namawala and Idete villages in southern Tanzania experienced extremely high malaria transmission the 1990s. By 2001-03, following usage rates (75% all age groups) untreated bed nets, a 4.2-fold reduction intensity was achieved. Since 2006, national-scale programme has promoted use longer-lasting insecticide treatment kits (consisting an plus binder) co-packaged with nets manufactured country. entomological inoculation rate (EIR) estimated through monthly surveys 72 houses...
Abstract. Various combinations of six candidate attractants ‐butanone, carbon dioxide (CO 2 ), honey, octenol, lactic acid and mixed phenols ‐ were tested against natural populations mosquitoes in Everglades National Park, Florida, U.S.A., using unlighted CDC‐baited traps. With few exceptions, the attractancy these compounds to mosquitoes, when used alone, was less than that CO alone. The exceptions octenol honey extract alone attracted larger numbers Coquillettidiaperturbans (Walker)....
Abstract Background Host-seeking of the African malaria mosquito, Anopheles gambiae sensu stricto , is guided by human odours. The precise nature odours, and composition attractive blends volatiles, remains largely unknown. Skin microbiota plays an important role in production body It hypothesized that host attractiveness selection An. affected species composition, density, metabolic activity skin microbiota. A study presented which constituency volatile organic compounds (VOCs) examined...
Carbon dioxide (CO2) plays an important role in the host-seeking process of opportunistic, zoophilic and anthropophilic mosquito species is, therefore, commonly added to sampling tools. The African malaria vector Anopheles gambiae sensu stricto is attracted human volatiles augmented by CO2. This study investigated whether CO2, usually supplied from gas cylinders acquired commercial industry, could be replaced CO2 derived fermenting yeast (yeast-produced CO2). Trapping experiments were...