A5072978427- Solid State Laser Technologies
- Laser Design and Applications
- Tunneling and Rock Mechanics
- Iterative Learning Control Systems
- Optical Systems and Laser Technology
- Advanced Surface Polishing Techniques
- Advanced Fiber Laser Technologies
- Advanced Measurement and Metrology Techniques
- Photorefractive and Nonlinear Optics
- Inertial Sensor and Navigation
- Advanced Sensor and Control Systems
- Plant Molecular Biology Research
- Diamond and Carbon-based Materials Research
- Drilling and Well Engineering
- Adaptive Control of Nonlinear Systems
- Genetics, Aging, and Longevity in Model Organisms
- Geophysics and Sensor Technology
- Mineral Processing and Grinding
- 3D Printing in Biomedical Research
- Control Systems in Engineering
- Hydraulic and Pneumatic Systems
- Plant Reproductive Biology
- Welding Techniques and Residual Stresses
- Optical measurement and interference techniques
- Photosynthetic Processes and Mechanisms
Huazhong University of Science and Technology
2015-2025
Chinese University of Hong Kong
2022-2024
Jiangsu Key Laboratory of 3D Printing Equipment and Manufacturing
2021
State Key Laboratory of Digital Manufacturing Equipment and Technology
2021
Chongqing University of Technology
2021
University of Liverpool
2018
University of Chinese Academy of Sciences
2016
Dalian Institute of Chemical Physics
2015
Chinese Academy of Sciences
2015
Harbin Institute of Technology
2010-2012
The blood-brain barrier (BBB) restricts the uptake of many neuro-therapeutic molecules, presenting a formidable hurdle to drug development in brain diseases. We proposed new and dynamic vivo-like three-dimensional microfluidic system that replicates key structural, functional mechanical properties vivo. Multiple factors this work synergistically accentuate BBB-specific attributes-permitting analysis complex organ-level responses both normal pathological microenvironments tumors. BBB...
Abstract We report that the Arabidopsis thaliana mutant sensitive to ABA and drought2 (sad2), which harbors a T-DNA insertion in an importin β-like gene, is more tolerant UV-B radiation than wild type. Analysis of cyclobutane pyrimidine dimer accumulation revealed less DNA damage occurred sad2 type during treatment. No significant growth difference was observed between when treated with genotoxic drug methyl methanesulfonate, suggesting SAD2 functions protection rather repair. Whereas...
Microfilament dynamics play a critical role in regulating stomatal movement; however, the molecular mechanism underlying this process is not well understood. We report here identification and characterization of STOMATAL CLOSURE-RELATED ACTIN BINDING PROTEIN1 (SCAB1), an Arabidopsis thaliana actin binding protein. Plants lacking SCAB1 were hypersensitive to drought stress exhibited reduced abscisic acid-, H(2)O(2)-, CaCl(2)-regulated movement. In vitro vivo analyses revealed that binds,...
An efficient 2 μm in-band pumped Ho:YAG laser was demonstrated. The resonator involves two crystals, each of which dual-end-pumped by orthogonally polarized diode-pumped Tm:YLF lasers. maximum continuous wave output power 103 W achieved, corresponding to a slope efficiency 67.8% with respect the incident pump and an optical-to-optical conversion 63.5%. Under Q-switched mode, we obtained 101 at 30 kHz, 66.2%. beam quality or M2 factor found be less than 2.
This article presents a novel linear active disturbance rejection control (LADRC) scheme based on internal model (IMC) rules and extended state observer (ESO) for high-performance motion of servo motor systems with input delay disturbances. The standard IMC (S-IMC) is employed to tune the gains LADRC specified set-point tracking, as well ESO handle external disturbances nominal model. However, due limited bandwidth in networked system (NCS), effect cannot be fully eliminated, which may have...
High power diode-pumped continuous wave (CW) and Q-switch operation of Tm,Ho:YVO4 laser is reported. Using two rods in a single cavity, up to 20.2 W CW output lasing at 2054.7 nm was obtained under cryogenic temperature 77 K with an optical conversion efficiency 32.9%. For operation, 19.4 15 kHz pulse repetition frequency (PRF) minimum width 24.2 ns. In addition, different frequencies 10.0 kHz, 12.5 15.0 were investigated comparatively.
A multifunctional droplet microdevice was presented for the post-embryonic development study of<italic>C. elegans</italic>initiating from L1 stage, and effect of HIF-1 on worm investigated.
Precise assessment of the mechanical properties soft biological systems at nanoscale is crucial for understanding physiology and pathology developing relevant drugs. Conventional atomic force microscopy (AFM)-based indentation methods suffer from uncertainties in local tip-sample interactions model choice. This can be overcome by adopting spatially resolved nonlocal deformation sensing analysis. However, technique currently limited to lifeless/static due inadequate spatial or temporal...
A microdevice to model type 2 diabetes-like hyperglycemia in<italic>C. elegans</italic>and examine several aspects of this disease elegans</italic>.
Spatial light modulators (SLM's) addressed with Computer Generated Holograms (CGH's) can create structured fields on demand when an incident laser beam is diffracted by a phase CGH.The power handling limitations of these devices based liquid crystal layer has always been some concern.With careful engineering chip thermal management, we report the detailed optical and temperature response cooled SLM exposed to picosecond powers up <P> = 220W at 1064nm.This information critical for determining...
A phase-field model is applied to study competitive dendritic growth between different grains with crystalline orientations during laser welding of Al-Cu alloy. An unfavorable oriented (UO) grain set locate two favorable (FO) the behaviors at not only converging boundary (GB) but also diverging GB. It found that cellular dendrites appear firstly nearby GBs initial instability stage. At early stage, UO misalignment angle influences both GBs. After completely entering leading are much faster...
Precise evaluation of the temperature and its evolution at microscopic scale in an operating electrochemical device is essential for accessing mechanism behind performance thermal management. However, such information limited, as most existing monitoring processes are carried out macroscale. Fluorescent nanodiamond (ND) enables sensitive nanoscale a working without perturbing processes. In this study, we demonstrated spatially resolved zinc (Zn) electroplating process, when fluctuation...
We report a ZGP OPO system capable of producing >6 W at signal wavelength 3.80 μm and an idler 4.45 μm. The pumping source is the Tm,Ho:GdVO4 laser operated 2.049 with M 2 1.07. generated total combined output power 6.1 under 18.3 W, 1.7 for was obtained.
In this article, a predictive active disturbance rejection control (ADRC) scheme is proposed for high-precision position tracking of servo systems with communication delays via sliding mode approach. the framework, filtered state predictor employed to handle time in networked system. Based on states, linear extended observer used compensate unknown perturbations ADRC, and boundary layer solution applied internal model rules robust control. Since can alleviate effect ignored high-frequency...
In the process of full-face tunnel boring machine (TBM) tunneling, pitch angle measurement accuracy laser target is greatly reduced by low frequency vibrations with large amplitude and multiple degrees freedom. order to improve under vibration, a three-degree-of-freedom (3-DOF) active vibration isolation system designed in this paper. A plate-type voice coil motor air gap thrust based on genetic algorithm. increase damping system, an eddy current damper combining copper plate permanent...
With the digitalization of power grids and development new systems, more IoT terminals are used in various scenarios grid business transmission distribution, so as to realize full perception system status service penetration all links electric energy production, consumption, ensure high-quality construction grids. The explosive growth number (such sensor devices, inspection robots, etc.) has transformed IT infrastructure from "boundary" "borderless", network security boundary is gradually...
In this paper, we report the performance of a diode-pumped cryogenic Tm (5 at %), Ho (0.5 %):GdVO4 laser with an RTP pockel cell Q-switch different pulse repetition rate including 300 Hz, 500 1 kHz, and 10 kHz. At pump power 6.96 W, maximum output 1.7 mJ width 28 ns was achieved under Hz rate, corresponding to peak 61 kW. To best our knowledge, is first time that used as generator in 2 μm Tm,Ho:GdVO4 laser.