- Solid State Laser Technologies
- Advanced Fiber Laser Technologies
- Laser Design and Applications
- Photorefractive and Nonlinear Optics
- Laser-Matter Interactions and Applications
- Diamond and Carbon-based Materials Research
- Photonic Crystal and Fiber Optics
- Spectroscopy and Laser Applications
- Luminescence Properties of Advanced Materials
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebrospinal fluid and hydrocephalus
- Alcohol Consumption and Health Effects
- Gut microbiota and health
- Graphene research and applications
- High-pressure geophysics and materials
- Machine Learning in Healthcare
- Metabolomics and Mass Spectrometry Studies
- Spinal Dysraphism and Malformations
- Traumatic Brain Injury and Neurovascular Disturbances
- Laser Material Processing Techniques
- Cyclopropane Reaction Mechanisms
- COVID-19 and Mental Health
- Fibroblast Growth Factor Research
- Synthesis and Catalytic Reactions
- GNSS positioning and interference
First Affiliated Hospital of Harbin Medical University
2023-2025
Harbin Medical University
2023-2025
Yantai University
2017-2024
Huzhou University
2024
Harbin University of Science and Technology
2021-2023
Shanxi Medical University
2023
Systèmes avancés de délivrance de principes actifs
2019
Harbin Institute of Technology
2012-2016
Anhui Medical University
2014
Zhejiang University
2011
An efficient 2 μm in-band pumped Ho:YAG laser was demonstrated. The resonator involves two crystals, each of which dual-end-pumped by orthogonally polarized diode-pumped Tm:YLF lasers. maximum continuous wave output power 103 W achieved, corresponding to a slope efficiency 67.8% with respect the incident pump and an optical-to-optical conversion 63.5%. Under Q-switched mode, we obtained 101 at 30 kHz, 66.2%. beam quality or M2 factor found be less than 2.
We reported a high-power ZnGeP₂ (ZGP) optical parametric oscillator (OPO) pumped by Q-switched Ho:YAG laser. The maximum output power of the ZGP OPO was 41.2 W at 107.0 incident Ho pump power, corresponding to slope efficiency 44.6%. produced 16-ns mid-IR pulse laser in 3.74-3.98 μm and 4.38-4.76 spectral regions simultaneously. beam quality measured be M²<4.37. continuous wave average 128 W, 65.8%.
The active/passive Q-switching operation of a 2 μm a-cut Tm,Ho:YAP laser was experimentally demonstrated with an acousto-optical Q–switch/MoS2 saturable absorber mirror. active Q-switch operated for the first time, to best our knowledge, average output power 12.3 W and maximum pulse energy 10.3 mJ. passive also acquired 3.3 W per 23.31 μJ, beam quality factors Mx2=1.06 My2=1.06 were measured at 2 W.
We, for the first time, demonstrate a tunable mid-infrared BaGa4Se7-based optical parametric oscillator pumped by acousto-optical Q-switched Ho:YAG laser at 2090.6 nm. Up to 1.55 W of average power was generated in 3-5 μm range, corresponding an optical-to-optical conversion efficiency 14.4% and slope 19.9%. The mid-IR radiation spectra were also seriously researched different phase-matched angles. range 3.49-4.13 signal, 5.19-4.34 idler.
ABSTRACT Hemorrhagic stroke (HS) mainly includes intracerebral hemorrhage (ICH) and subarachnoid (SAH), both of which seriously affect the patient's prognosis. Cerebrospinal fluid (CSF) metabolites HS showed a link in observational studies. However, causal association between them is not clear. We aimed to establish optimal causality CSF with HS. Mendelian randomization (MR) was employed identify associations different sources Univariable MR false discovery rates (FDR) were used initial...
Aim This study aims to investigated the associations between estimated plasma volume status (ePVS) and 30-day 1-year mortality in intracerebral hemorrhage (ICH) patients, providing insights into management ICH. Methods Data of adult ICH patients were extracted from both Medical Information Mart for Intensive Care IV (MIMIC-IV) database Hospital System (HIS) this retrospective cohort study. Univariate multivariate Cox regression analyses, restricted cubic spline plots (RCS) conducted explore...
We demonstrated a 1.91 μm pumped, injection-seeded Q-switched Ho:YAG laser operating at room temperature. By inserting two Fabry-Perot etalons into the cavity, single-frequency Tm, seed lasing was achieved wavelength of 2090.9 nm, with typical output power 60 mW. Single-frequency, nearly transform-limited operation by injection seeding. The energy pulse is 7.6 mJ, width 132 ns and repetition rate 100 Hz. measured spectrum, half-width which 3.5 MHz, heterodyne technique.
We used the Cr2+:ZnS as a saturable absorber to obtain passively Q-switched Ho:YAG ceramic laser operating near 2.1 μm. The maximum average output power of 14.8 W and shortest pulse width 29 ns were obtained, our knowledge, this is best report for PQS laser. A energy per 0.6 mJ with repetition frequency 24.4 kHz was achieved, which corresponded peak 20 kW. first pump source optical parametric oscillator mid-infrared 4.4 achieved from ZnGeP2 oscillator, corresponding slope efficiency 49.5%...
We have successfully achieved the synthesis of heterojunction consisting WSe 2 and BN, by using a liquid phase exfoliation method, characterization prepared materials under microstructure. The /BN was used as saturable absorber in Tm:YAP laser for passively Q-switched operation, pulsed with an output wavelength around µm range obtained. After comparing effects resonators composed different cavity mirrors, it is concluded that when curvature radius input mirror 250 mm transmittance coupler...
Background Recent studies have suggested that the composition of gut microbiota (GM) may change after intracerebral hemorrhage. However, causal inference GM and hemorrhagic stroke is unknown. Mendelian Randomization (MR) an effective research method removes confounding factors investigates relationship between exposure outcome. This study intends to explore with help MR. Methods Univariable multivariable MR analyses were performed using summary statistics ( n = 18,340) in MiBioGen consortium...
Background Hemorrhagic stroke (HS), a leading cause of death and disability worldwide, has not been clarified in terms the underlying biomolecular mechanisms its development. Circulating metabolites have closely associated with HS recent years. Therefore, we explored causal association between circulating metabolomes using Mendelian randomization (MR) analysis identified molecular effects. Methods We assessed relationship serum (CSMs) bidirectional two-sample MR method supplemented five...
Boron nitride (BN) nanosheets are prepared using an ultrasonic decomposition method and demonstrated nonlinear absorption characteristics that saturated at near 2 µm. A passively mode‐locked Tm:YAP laser was perfectly implemented with the BN as a saturable absorber (SA). In Q‐switched mode, average output power of 880 mW pulse duration 478.83 ps achieved incident pump 26.46 W, corresponding to optical–optical conversion efficiency 3.33%. peak 19.03 W acquired 1937.0 nm from laser.
It is reported in this paper that a cavity-dumped electro-optically Q-switched Tm:LuAG oscillator offers unique combination of high power, constant short pulse duration, and repetition rate at wavelength 2012.7 nm. The durations 3 ns were achieved by the technology different rates from 60 to 100 kHz. An average power 1.22 W peak 4.1 kW obtained kHz an incident pump 42.3 W, corresponding slope efficiency 6% beam quality factor M2∼1.4. In addition, accumulation time intracavity photons 500...
In this paper, we demonstrate the continuous-wave and acousto-optical Q-switched performance of diode-pumped slab Ho:(Sc0.5Y0.5)2SiO5 (Ho:SYSO) laser at 2.1 µm for first time. Two 1.91-µm diodes were used to pump Ho:SYSO crystal. With a wing-pumping structure, absorbed power 44.7 W, continuous wave produced 20.7 W maximum output 2097.9 nm, resulting in slope efficiency 53.1% with respect power. regime, up 3.4 mJ pulse energy 20 ns minimum width repetition frequency 5 kHz, corresponding peak 170 kW.
We demonstrated a 1.91 μm-pumped, injection-seeded Ho:YAG laser operating at room-temperature. Single-frequency, nearly transform-limited Q-switched operation of the was achieved by injection-seeding. Using monolithic nonplanar ring oscillator (NPRO) as seed laser, 11 mJ single-frequency 110 Hz with pulse width ns obtained. The beam quality factor measured to be M2 < 1.1 traveling knife-edge method maximal output level. spectrum, half-width which 4.8 MHz, heterodyne technique.
In this paper we present a high power long-wave infrared ZnGeP2 (ZGP) optical parametric amplifier (OPA) pumped by 2097-nm Q-switched Ho:YAG laser with pulse repetition frequency of 20 kHz. When the incident Ho pump was 116.0 W, maximum average output 11.4 W at 8.3 μm achieved in ZGP OPA. The conversion efficiency from to about 9.8%. OPA produced 30.4 ns pulse. beam quality factor (M2) measured be 2.9 power.