- Malaria Research and Control
- Global Maternal and Child Health
- Health disparities and outcomes
- Child Nutrition and Water Access
- Mosquito-borne diseases and control
- Global Health Care Issues
- Spectroscopy and Chemometric Analyses
- Advancements in Transdermal Drug Delivery
- Global Public Health Policies and Epidemiology
- Adolescent Sexual and Reproductive Health
- Blood Pressure and Hypertension Studies
- Thermal and Kinetic Analysis
- Wound Healing and Treatments
- Chronic Disease Management Strategies
- Analytical Chemistry and Chromatography
- Surgical Sutures and Adhesives
- Poverty, Education, and Child Welfare
- HIV/AIDS Research and Interventions
- Chemical Thermodynamics and Molecular Structure
- Diabetes Management and Education
- Bee Products Chemical Analysis
- Complement system in diseases
- Obesity, Physical Activity, Diet
- Global Cancer Incidence and Screening
- Tuberculosis Research and Epidemiology
University of Ghana
2010-2024
Noguchi Memorial Institute for Medical Research
2006-2024
Korle Bu Teaching Hospital
2019-2024
University of Bahrain
2015-2024
University of Leicester
2024
University of Greenwich
2008-2023
University of Health and Allied Sciences
2018-2019
University of Bath
2007
University of London
2007
Medway School of Pharmacy
2004-2005
Radial basis function (RBF) neural network models for the simultaneous estimation of flash point (Tf) and boiling (Tb) based on 25 molecular functional groups their first-order connectivity index (1χ) have been developed. The success whole modeling process depended a optimization strategy biharmonic spline interpolation selection an optimum number RBF neurons (n) in hidden layer associated spread parameter (σ). networks were trained by Orthogonal Least Squares (OLS) learning algorithm. After...
BackgroundRespiratory distress (RD), a symptom of underlying metabolic acidosis, has been identified as major risk factor for mortality in children with severe malaria Africa, yet the molecular mediators involved pathogenesis RD have not
Abstract Background Severe malarial anaemia (SMA) is a major life-threatening complication of paediatric malaria. Protracted production pro-inflammatory cytokines promoting erythrophagocytosis and depressing erythropoiesis thought to play an important role in SMA, which characterized by high TNF/IL-10 ratio. Whether this imbalance results from intrinsic incapacity SMA patients produce IL-10 or unresponsiveness infection unknown. Monocytes T cells are recognized as the main sources TNF vivo ,...
Depression and hypertension interact through a complex interplay of social, behavioral biological factors. Despite the huge burden in African sub-region, very little information exists on depression among hypertensive patients. This study assessed prevalence factors associated with young older adult patients Ghana. Data from World Health Organization Study Global AGEing Adult wave 2 (2014/2015) for Ghana was used. estimated participants blood pressure 140/90mmHg above. Weighted descriptive...
Abstract Background Ghana’s National Health Insurance Scheme has improved access to care, although equity and sustainability issues remain. This study examined health insurance coverage, type of payment for reasons being uninsured under the in Ghana. Methods The 2014 Ghana Demographic Survey datasets with information 9396 women 3855 men were analyzed. employed cross-sectional national representative data. frequency distribution socio-demographics coverage differentials among is first...
Aim To estimate the prevalence of visual impairment (VI) and associated factors further quantify its association with social isolation, depression life satisfaction among older adults in Ghana. Methods WHO Study on Global AGEing Adult Health Ghana dataset for 50 years above was used this study. Social were our primary outcomes VI being secondary outcome. We employed negative binomial, Poisson generalised binomial regression models individually modified Coarsened Exact Matching method...
Background The epidemiology of Mycobacterium tuberculosis complex (MTBC) lineage 5 (L5) infections in Ghana revealed a significantly increased prevalence Ewes compared to other self-reported ethnic groups. In that context, we sought investigate the early phase (TB) infection using ex vivo macrophages derived from blood Ewe and Akan group volunteers with MTBC L4 L5 strains. Methods study participants consisted 16 controls, among which ethnicity was equally represented, as well 20 cured TB...
This study was conducted to assess the prevalence and factors associated with Food Insecurity (FI) further quantify its association unmet need for health services health-related outcomes among older adults aged 50 years above in Ghana. The Ghana Study on Global AGEing Adult Health used. Body Mass Index (BMI), depressive episodes, functional difficulties (FD), low Quality of Life (QoL), memory decline, Unmet Needs Services (UNHS) are outcomes. Ordinary Least Square, Poisson regression...
Cardiovascular diseases (CVD) are the leading cause of death worldwide, with 80% these deaths occurring in low-middle income countries (LMICs). In Ghana and across Africa, CVDs have emerged as causes primarily due to undetected under treated hypertension, yet less than 5% resources allocated health resource-poor go into non-communicable (NCD) including CVD prevention management. Consequently, most Africa do not contextually appropriate sustainable system framework prevent, detect manage...
The identification and quantification of volatile species formed in the thermal degradation tobacco substrates was investigated by TG-FTIR analysis. A specific experimental methodology developed to obtain quantitative data on key components interest present evolved gases during runs air nitrogen at low heating rates. Multivariate deconvolution techniques were used identify contributions overall FTIR spectra. Validation carried out test limits technique. Significant obtained for...
Background Functional difficulty assessment has been proven as a key factor in the health evaluation of adults. Previous studies have shown reduction and functional difficulties with increasing age. This analysis was conducted to quantify effect poor self-rated on among older adults Ghana. Method based World Health Organization Study Global AGEing Adult Ghana for 50 years above. Fifteen standard functioning tools were extracted used analysis. Three predictive models Coarsened Exact Matching...
Background Pregnant teenage women are prime targets of violence against perpetrated by intimate partners, family members, and miscreants in their neighborhoods. This study estimated the prevalence Teenage pregnancy (TP) Physical Violence (PV) further assessed relationship between TP PV five Low-and-Middle-Income Countries (LMICs). Methods The was conducted among LIMCs (Burkina Faso, Kenya, Malawi, Nigeria, Tanzania) using data from most recent Demographic Health Surveys these countries....
Alcohol consumption and inadequate fruits vegetable (FnV) intake are major reasons for the shift from communicable to non-communicable diseases (NCDs) over years. The older Ghanaian adult is at high risk of NCD data on alcohol FnV required guide policy mitigate its effect. This analysis aimed determine factors associated with assess relationship between among Ghanaians aged 50 years older.This used WHO Study Global Ageing Adult Health (SAGE) Wave 2, Ghana set conducted 2014 2015. Data...
Annals of Global Health is a peer-reviewed, fully open access, online journal dedicated to publishing high quality articles all aspects global health. The journal's mission advance health, promote research, and foster the prevention treatment disease worldwide. Its goals are improve health well-being people, equity, wise stewardship earth's environment. latest impact factor 2.90. supported by Program for Public Common Good at Boston College. It was founded in 1934 Icahn School Medicine Mount...
Background Early secretory antigenic target 6 (ESAT-6) and culture filtrate protein 10 (CFP-10) are Mycobacterium tuberculosis (Mtb)–specific antigens that secreted by actively metabolising bacteria contribute to the virulence of bacteria. Their ability induce Treg Th2 responses, particularly during first two weeks treatment, has not been comprehensively examined date. The purpose this work was characterise Th1, responses rESAT-6-CFP10 fusion in TB patients before intensive phase treatment...
The association between substance use including marijuana and attempted suicide has been well documented. However, little is known about its with repetition among young people in low-income middle-income contexts.This analysis was conducted to assess the factors associated ascertain as a determinant of repeated senior high school (SHS) students Ghana.Data from 2012 Global School-Based Student Health Survey Ghana used for this study. Modified Poisson, Logistic Probit models weighted...