A5067274753- HIV/AIDS Research and Interventions
- Frailty in Older Adults
- HIV Research and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- HIV/AIDS Impact and Responses
- Health disparities and outcomes
- Global Health Care Issues
- HIV/AIDS drug development and treatment
- Geriatric Care and Nursing Homes
- HIV-related health complications and treatments
- Nutrition and Health in Aging
- Chronic Disease Management Strategies
- Adolescent Sexual and Reproductive Health
- Global Maternal and Child Health
- Aging and Gerontology Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Allergic Rhinitis and Sensitization
- Hepatitis B Virus Studies
- HIV, Drug Use, Sexual Risk
- Cytomegalovirus and herpesvirus research
- Asthma and respiratory diseases
- Poverty, Education, and Child Welfare
- Healthcare Systems and Practices
- Climate Change and Health Impacts
- Hepatitis C virus research
University of Rome Tor Vergata
2016-2025
Newcastle University
2020
National Pingtung University
2020
SGH Warsaw School of Economics
2020
Teikyo University
2020
Fukuda Denshi (Japan)
2020
Uniwersytet Komisji Edukacji Narodowej w Krakowie
2020
University Medical Center Utrecht
2017
Gates Foundation
2016
Libera Università Maria SS. Assunta
2015-2016
Older adults are the main victims of novel COVID-19 coronavirus outbreak and elderly in Long Term Care Facilities (LTCFs) severely hit terms mortality. This paper presents a quantitative study impact Italy during first stages epidemic, focusing on effects mortality increase among older over 80 its correlation with LTCFs. The growth patterns shows power-law scaling regime for stage pandemic an uneven behaviour different regions as well overall according to COVID-19. However, incidence rate...
The response to treatment and risk factors for early mortality following initiation of combination antiretrovirals (ARVs) in a cohort African patients are described retrospective design. Medical history, laboratory parameters, data were reviewed initiating ARVs 12 clinical centers Mozambique, Tanzania, Malawi. Among 3456 HIV-1-infected who received more than 6 months, at baseline 72% had WHO stages 3/4, 7% viral load <400 copies/ml, 38% CD4 cell count >200/μl. One year later, 78%...
Objective: To evaluate pregnancy outcomes in a cohort of HIV-infected women receiving triple antiretroviral therapy (ART) for prevention mother-to-child-transmission. Methods: A retrospective study with review records 3273 HIV-positive prenatal care Malawi and Mozambique from July 2005 to December 2009 was conducted Drug Resource Enhancement Against AIDS Malnutrition (DREAM) centers. Patients were offered nevirapine-based ART initiated until 6 months postpartum. Main outcome measures...
Italy was one of the first European countries affected by new coronavirus (COVID-19) pandemic, with over 105,000 infected people and close to 13,000 deaths, until March 31st. The pandemic has hit especially hard because country's demographic structure, a high percentage older adults. authors explore possibility, recently aired in some studies, extensive intergenerational contact as possible determinant severity among Italian We analyzed several variables test this hypothesis, such patients...
BackgroundOptimized preventive strategies are needed to reach the objective of eliminating pediatric AIDS. This study aimed define determinants residual HIV transmission in context maternal antiretroviral therapy (ART) administration pregnant women, assess infant safety this strategy, and evaluate its impact on disease. Methodology/Principal FindingsA total 311 HIV-infected women were enrolled Malawi an observational received a nevirapine-based regimen from week 25 gestation until 6 months...
The Strategic Implementation Plan of the European Innovation Partnership on Active and Healthy Ageing (EIP AHA) proposed six Action Groups. After almost three years activity, many achievements have been obtained through commitments or collaborative work However, they often worked in silos and, consequently, synergies between Groups to strengthen triple win EIP AHA. paper presents methodology current status Task Force AHA synergies. Synergies are line with Groups' new Renovated (2016-2018)...
OPINION article Front. Med., 30 April 2018 | https://doi.org/10.3389/fmed.2018.00123
Patients with psychiatric disorders face exacerbated physical health issues and reduced life expectancy, primarily due to premature cardiovascular diseases. The intricate relationship between lifestyle factors, illness, psychotropic medications contributes this phenomenon. focus of research is evaluate weight management interventions for individuals Severe Mental Disorders through a comprehensive scoping review, investigating the characteristics, types, modalities topics provide useful tool...
Objective To assess the incidence and consequences of adverse reactions among African HIV‐positive pregnant women treated with fixed‐dose combinations a nevirapine‐containing antiretroviral (ARV) triple therapy. Methods A retrospective analysis clinical files 703 HIV‐1‐positive regimen between May 2002 July 2004 was conducted. Selection criteria for inclusion in were: (a) taking ARV more than 14 days; (b) baseline values transaminases below threshold 2.5 times upper limit normal (ULN). The...
HIV-infected patients have increased risk of noncommunicable diseases (NCDs). HIV+ in Africa are experiencing growing comorbidities due to increase life expectancy and long-time antiretroviral therapy (ART). HIV prevalence Malawi is one highest the world (10.8% women 6.4% men); few data available about NCDs epidemiology elderly Malawi. A retrospective analysis routine medical records 14 health centers run by Disease Relief through Excellent Advanced Means (DREAM) program was carried out. All...
Background HIV infection is a major contributor to maternal mortality in resource-limited settings. The Drug Resource Enhancement Against AIDS and Malnutrition Programme has been promoting HAART use during pregnancy postpartum for Prevention-of-mother-to-child-HIV transmission (PMTCT) irrespective of CD4 cell counts since 2002. Methods Records all HIV+ pregnancies followed Mozambique Malawi from 6/2002 6/2010 were reviewed. cohort was comprised by where women referred PMTCT started prenatal...
Limited information is available on antiretroviral concentrations in women/infant pairs receiving prophylaxis for breastfeeding transmission of HIV and the relationship between drug levels virological haematochemistry parameters.Patient population included HIV-positive pregnant women from gestational week 25 until 6 months after delivery their breastfed infants. Blood breast milk samples were collected at delivery, 1, 3 postpartum. Drug measured by liquid chromatography-mass...
To evaluate antiretroviral drug concentrations in mothers and infants enrolled under the Option B-Plus approach for prevention of HIV mother-to-child transmission Malawi to assess maternal virological response after 1 year treatment. Forty-seven women 25 children were studied. Mothers administered during pregnancy a combination tenofovir, lamivudine efavirenz continued it breastfeeding (up 2 years) thereafter. Drug evaluated (plasma breast milk) at 12 months post-partum (plasma) 6 age....
This study focuses on the impact of a program aimed at reducing heat-related mortality among older adults residing in central Rome by counteracting social isolation. The citizens over age 75 living three Urban Areas (UAs) located is compared with that residents four adjacent UAs during summer 2015. data, broken down UA, were provided Statistical Office Municipality Rome, which gathers them routine basis. During 2015, 167 deaths recorded those Long Live Elderly (LLE) was active and 169 it...
Lowering mortality and hospitalization of older adults is one the main goals public health to improve both systems' sustainability adults' quality life. The aim this study identify determinants associated with use hospital services in population than 64 years age.A randomized sample from Lazio region (Italy) above age was enrolled 2014 by administration a questionnaire assess frailty; rates year following enrolment have been retrieved regional database. Univariable multivariable analyses...
Heat waves are correlated with increased mortality in the aged population. Social isolation is known as a vulnerability factor. This study aims at evaluating correlation between an intervention to reduce social and increase population over 80 during heat waves.This adopted retrospective ecologic design. We compared excess rate (EMR) over-80 urban areas of Rome (Italy) where program was implemented, others it not implemented. measured summer periods from 2015 2019 2014 (a year without waves)....
The administration of antiretroviral therapy to lactating women could represent a possible strategy reduce postnatal HIV transmission. In this study, we assessed the effect treatment on breast milk viral load and determined plasma drug concentrations in pregnant receiving highly active (HAART).We studied 40 zidovudine, lamivudine, nevirapine from 28 weeks gestation 1 month postpartum (group A) untreated B). Blood samples were collected at delivery 7 days postpartum.Women group A had received...
Abstract Non-communicable chronic diseases (NCCDs) are the main cause of morbidity and mortality globally. Demographic aging has resulted in older populations with more complex healthcare needs. This necessitates a multilevel rethinking policies, health education community support systems digitalization technologies playing central role. The European Innovation Partnership on Active Healthy Aging (A3) working group focuses well-being for adults, an emphasis quality life healthy aging. A...