A5000396607- Cellular transport and secretion
- Endoplasmic Reticulum Stress and Disease
- Plant Reproductive Biology
- Lysosomal Storage Disorders Research
- Lipid Membrane Structure and Behavior
- Photosynthetic Processes and Mechanisms
- Autophagy in Disease and Therapy
Institute of Crop Sciences
2020-2024
Chinese Academy of Agricultural Sciences
2020-2024
Dense vesicles (DVs) are vesicular carriers, unique to plants, that mediate post-Golgi trafficking of storage proteins protein vacuoles (PSVs) in seeds. However, the molecular mechanisms regulating directional targeting DVs PSVs remain elusive. Here, we show rice (Oryza sativa) glutelin precursor accumulation5 (gpa5) mutant is defective PSVs, resulting discharge its cargo into extracellular space. Molecular cloning revealed GPA5 encodes a plant-unique phox-homology domain-containing...
Protein storage vacuoles (PSVs) are unique organelles that accumulate proteins in plant seeds. Although morphological evidence points to the existence of multiple PSV-trafficking pathways for protein targeting, molecular mechanisms regulate these processes remain mostly unknown. Here, we report functional characterization rice (Oryza sativa) glutelin precursor accumulation7 (gpa7) mutant, which over-accumulates 57-kDa precursors dry Cytological and immunocytochemistry studies revealed gpa7...
ABSTRACT Autophagy is a highly conserved cellular program in eukaryotic cells which mediates the degradation of cytoplasmic components through lysosome, also named vacuole plants. However, molecular mechanisms underlying fusion autophagosomes with remain unclear. Here, we report functional characterization rice ( Oryza sativa ) mutant defects storage protein transport endosperm and accumulation numerous root cells. Cytological immunocytochemical experiments showed that this exhibits defect...
Abstract Coat protein complex II (COPII) vesicles play crucial roles in mediating the endoplasmic reticulum (ER) exit of newly synthesized proteins to Golgi eukaryotic cells. However, molecular functions COPII components and their functional diversifications plant seeds remain obscure. Here, we showed that rice (Oryza sativa) glutelin precursor accumulation12 (gpa12) mutant is defective storage export from ER, resulting formation aggregated bodies. Map-based cloning revealed GPA12 encodes a...