A5043913921- Mechanical Behavior of Composites
- Composite Material Mechanics
- Nanoparticle-Based Drug Delivery
- Fatigue and fracture mechanics
- Mechanical stress and fatigue analysis
- Hydrogels: synthesis, properties, applications
- Composite Structure Analysis and Optimization
- Aluminum Alloys Composites Properties
- Nanoplatforms for cancer theranostics
- Computational Drug Discovery Methods
- Advanced ceramic materials synthesis
- RNA Interference and Gene Delivery
- Polymer Surface Interaction Studies
- Photodynamic Therapy Research Studies
- Ferroptosis and cancer prognosis
- Advanced Sensor and Energy Harvesting Materials
- Bioactive Compounds and Antitumor Agents
- Structural Behavior of Reinforced Concrete
- Machine Learning in Materials Science
- RNA modifications and cancer
- Graphene and Nanomaterials Applications
- Structural Health Monitoring Techniques
- Cancer therapeutics and mechanisms
- Synthesis and biological activity
- Numerical methods in engineering
Guangxi University
2019-2025
Shanghai Jiao Tong University
2016-2024
Jiujiang First People's Hospital
2024
Jiangsu University
2021-2023
First People's Hospital of Kunshan
2021-2023
Guangxi Medical University
2021-2023
Nantong University
2023
Cancer treatment is presently a significant challenge in the medical domain, wherein primary modalities of intervention include chemotherapy, radiation therapy and surgery. However, these therapeutic carry side effects. Photothermal (PTT) photodynamic (PDT) have emerged as promising for tumors recent years. Phototherapy approach that involves exposure materials to specific wavelengths light, which can subsequently be converted into either heat or Reactive Oxygen Species (ROS) effectively...
Objective: To verify the ability of deep learning model in identifying five subtypes and normal images noncontrast enhancement CT intracranial hemorrhage. Method: A total 351 patients (39 group, 312 hemorrhage group) performed with enhanced were selected, 2768 (514 for 398 epidural 501 subdural 497 intraventricular 415 cerebral parenchymal 443 subarachnoid group). Based on diagnostic reports two radiologists more than 10 years experience, ResNet-18 DenseNet-121 models selected. Transfer was...
Abstract Photodynamic therapy (PDT) is extensively investigated for tumor in the clinic. However, efficacy of PDT severely limited by tissue penetrability light, short effective half‐life and radius reactive oxygen species (ROS), weak immunostimulatory effect. In this study, a glutathione (GSH)‐activatable nano‐photosensitizer developed to load with arachidonic acid (AA) camouflage erythrocyte membrane, which serves as laser‐ignited lipid peroxidation nanoamplifier (MAR). The photosensitive...
This study aims to develop a dual-ligand-modified targeted drug delivery system by integrating photosensitizers and chemotherapeutic drugs enhance anti-glioma effects. The is designed overcome the blood-brain barrier (BBB) that hinders effective delivery, increase accumulation in glioma cells, thereby therapeutic efficacy.
Objective: We aimed analyze research trends in situ gel drug delivery systems. Methods: Studies from 2003 to 2023 were systematically obtained the Web of Science database and analyzed using VOSviewer software evaluate publication trends, citation patterns, collaborative networks. Results: A total 990 articles reviewed. There has been a significant increase publications since 2019, with highest number occurring 2023. China was leading country terms output. Cairo University King Abdulaziz...
To construct a novel nano-carrier with dual ligands to achieve superior anti-tumour efficacy and lower toxic side effects.
Excision repair cross‑complementation group 6 like (ERCC6L) has been reported to be upregulated in a variety of malignant tumors and plays critical oncogenic role. However, the role molecular mechanism ERCC6L lung adenocarcinoma (LUAD) remain unclear, were therefore investigated present study. Clinical data patients with LUAD obtained bioinformatics analysis was performed investigate expression characteristics, prognostic value, biological function ERCC6L. In addition, cell experiments...
MiRNAs are small non-coding RNAs modulating gene expression, and variants in miRNA genes involve the pathogenesis of ischemic stroke (IS). However, effect miR-34a polymorphisms on IS susceptibility has been rarely reported. In present study, we investigated association between rs12128240, rs2666433 rs6577555 susceptibility. Snapshot assay was used to detect 548 patients 560 controls. Relative expression measured by quantitative real-time PCR. We found that associated with a significantly...