A5091656483- Protein Interaction Studies and Fluorescence Analysis
- Nanoparticle-Based Drug Delivery
- Gold and Silver Nanoparticles Synthesis and Applications
- Protein purification and stability
- Bee Products Chemical Analysis
- Phytochemicals and Antioxidant Activities
- Radiation Effects and Dosimetry
- Laser-Ablation Synthesis of Nanoparticles
- Radioactive element chemistry and processing
- Advanced oxidation water treatment
- Hemoglobin structure and function
- Quantum Dots Synthesis And Properties
- Advanced Photocatalysis Techniques
- Nanoplatforms for cancer theranostics
- Nanoparticles: synthesis and applications
- Bone Tissue Engineering Materials
- Microfluidic and Capillary Electrophoresis Applications
- RNA Interference and Gene Delivery
- Enzyme Catalysis and Immobilization
- Electrospun Nanofibers in Biomedical Applications
- Polymer Surface Interaction Studies
- Monoclonal and Polyclonal Antibodies Research
- Lanthanide and Transition Metal Complexes
- Proteins in Food Systems
- Erythrocyte Function and Pathophysiology
National University of Quilmes
2014-2023
Consejo Nacional de Investigaciones Científicas y Técnicas
2014-2023
Instituto Multidisciplinario de Biología Celular
2015-2023
Instituto de Biotecnología y Biología Molecular
2021
In a biological environment, nanoparticles are rapidly coated with serum proteins, which affects the NPs transport through medium, cellular uptake and response, all of can impair therapeutic efficiency. Reduction non-specific adsorption proteins is mandatory to overcome this drawback. We propose use albumin prepare multilayer coating reduce protein interactions in media. Biohybrid (bioHNPs) prepared by gold finally decorated Bombesin-related peptides (BD-bioHNPs). BioHNPs/biological media...
Fusion of peptide‐based tags to recombinant proteins is currently one the most used tools for protein production. Also, immobilized metal ion affinity chromatography (IMAC) has a huge application in purification, especially research labs. The combination expression systems tagged with this robust chromatographic system become an efficient and rapid tool produce milligram‐range amounts proteins. IMAC‐Ni(II) columns have natural partners 6xHis‐tagged Ni(II) considered as best compromise...
Preparación de Nanopartículas Albúmina…….…………………………………….3 Albúminas: BSA y HSA………….……………………………………………………….. 4 2. Radiaciones ionizantes en síntesis o estabilización NPs……….……………….. 6 3. oro …………………………………………………………………… 7 Técnicas NPs …………………………………………………… Propiedades ópticas las Au-NPs -Resonancia plasmón superficial…….….. 8 aplicaciones liberación controlada …………………… 10 Terapia Fototérmica…………………………………….………………………………... 11 Radioterapia con como radiosensibilizadores….…………... 4. Nanosistemas...
Abstract A γ–irradiated bovine albumin serum based nanoparticle was characterised structurally, and functionally. The by A.F.M, D.L.S, zeta potential, T.E.M., gel-electrophoresis, spectroscopy (UV-Vis, Fluorescence, FT-IR, CD). Its stability studied under adverse experimental conditions: pH values, chaotropic agents, ionic strength studies against time were mainly carried out fluorescence following the changes in tryptophan environment nanoparticle. function interaction of NP with...
Anthocyanins are the main active compounds in blueberry. However, they have poor oxidation stability. If anthocyanins encapsulated protein nanoparticles, their resistance could be increased as a result of slowing down process. This work describes advantages using γ-irradiated bovine serum albumin nanoparticle bound to anthocyanins. The interaction was characterized biophysically, mainly by rheology. By computational calculation and simulation based on model we estimated number molecules...
En los últimos años, distintos enfoques basados en la Nanotecnología comenzaron a tener relevancia búsqueda de nuevas estrategias para el diagnóstico y terapia distintas enfermedades, entre ellas cáncer. este contexto, las nanopartículas oro (AuNPs) son nanomateriales inorgánicos más atractivos desde punto vista salud humana. Su superficie puede ser modificada fácilmente su utilización in vivo, mediante agregado señales direccionamiento células específicas o recubrimientos biocompatibles,...
The active blueberry compounds called anthocyanins have poor oxidation stability, but, if encapsulated by protein nanoparticles, they can be protected due to the slowing down of process. This work describes advantages using a γ-irradiated bovine serum albumin nanoparticle bound anthocyanins. interaction was characterized biophysically, mainly rheology. By computational calculation and simulation based on model we estimated number molecules forming which allowed us infer ratio...
The active blueberry compounds called anthocyanins have poor oxidation stability, but, if encapsulated by protein nanoparticles, they can be protected due to the slowing down of process. This work describes advantages using a γ-irradiated bovine serum albumin nanoparticle bound anthocyanins. interaction was characterized biophysically, mainly rheology. By computational calculation and simulation based on model we estimated number molecules forming which allowed us infer ratio...