The objectives of this study were to assess the black soldier fly larvae (BSFL) composting potential and analyse quality organic fertilizer produced for agricultural purposes. waste biodegradation was determined by varying feed treatment (2, 2.5, 3.0, 3.5, 4 kg) control (2 heterogeneous mixture municipal solid from market, restaurant households. Each setups received equal number viable (i.e. 2000) which 5–6 days old. To nutrient concentration compost residues with BSFL, substrate final...

The hypoglycaemic and anti-hyperlipidaemic effects of the 70% ethanol stem bark extract Myrianthus libericus (MLB), used traditionally in management diabetes Ghana, was evaluated this study using streptozotocin (45 mg/kg)-induced diabetic rats. In vitro activities one its principal compounds, friedelan-3-one were then investigated α-amylase inhibitory glucose uptake assay C2C12 myotubes. silico analysis pharmacokinetic toxicity properties compound also performed. MLB significantly (p <...

Vitex doniana Sweet fruit, an under-utilised crop specie of Ghana, has not been validated for its ethnomedical use in managing inflammatory conditions. Therefore, the study sought to investigate anti-inflammatory and antioxidant activities as well isolate quantify one active constituents.In-vivo activity methanol fruit extract was evaluated using carrageenan-induced oedema model chicks. The in-vitro property also investigated 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay....

The emergence and resurgence of P. falciparum resistance to generations antimalarial drugs have prompted the search for new, effective, safe agents. This study aimed at investigating in vivo antiplasmodial activity 70% hydroethanolic extract constituents stem bark Myrianthus libericus based on its ethnomedicinal use as an agent. was assessed Swiss albino mice employing 4‐day suppressive Rane’s tests. MLB significantly ( p &lt; 0.0001) suppressed parasitaemia by 52.26%, 65.40%, 77.11% 50,...

In the management of hypertension (a cardiovascular disease and leading metabolic risk factor in noncommunicable diseases) with herbal medicines, efficacy safety are uttermost concern. This study sought to establish hypotensive, antihypertensive, drug interaction, for use aqueous leaf extracts Annona muricata (AME), Persea americana (PAE), or their combination products (CAPE). Methodology. Systolic diastolic blood pressure (SBP DBP), mean arterial (MAP), heart rate (HR) were measured...

Reissantia indica (Willd.)Halle is employed widely in African folklore medicine for the mitigation of inflammatory conditions and certain cancers.However, scientific validation its anecdotal uses not widespread.The study validated antimicrobial, antioxidant, anti-inflammatory activities stem bark R. tracked down active constituents.The activity hydroethanolic extract isolates was evaluated using 7-day-old chick edema model with carrageenan as edemogenic agent.Antioxidant carried out by...

Microbial infections remain a public health problem due to the upsurge of bacterial resistance. In this study, antibacterial, antibiofilm, and efflux pump inhibitory activities stem bark Acacia macrostachya, an indigenous African medicinal plant, were investigated. traditional medicine, plant is used in treatment microbial inflammatory conditions. A crude methanol extract obtained by Soxhlet extraction was partitioned column chromatography obtain petroleum ether, ethyl acetate, fractions....

The stem bark of Cussonia bancoensis is used traditionally for the treatment different types infection and pain. A bioassay guided fractionation methanol extract led to isolation five pentacyclic triterpenes glycosides identified based on spectroscopic data as 23-hydroxyursolic acid (CB1), hederagenin (CB2), 3-O-α-L-arabinopyranosyl-echinocystic (CB3), 3-O-α-L-arabinopyranosyl- oleanolic (CB4) 3-O-α-L-arabinopyranosyl-ursolic (CB5). CB2 - CB5 are being reported first time from this species....

Buruli ulcer disease, a necrotising skin and subcutaneous tissue is endemic to tropical Africa. People in communities' resort topical oral consumption of plant extracts which have not been validated. The present study focused on validating the antimycobacterial properties toxicity different solvent stem bark P. angolensis establish pharmacognostic standards for quality control purposes. In vitro activity aqueous, 70% hydro-ethanol ethyl acetate against M. ulcerans (NM 203 strain) was done...

Tomato paste is the most consumed tomato product on Ghanaian market, majority of which are imported into country. This food easily adulterated, and thus, routine quality checks necessary. Therefore, current study aimed at assessing eight products market checking for presence starch artificial colourant erythrosine as possible adulterants. Routine metrics such pH, titratable acidity, total solids, soluble solids were assessed using standard methods. An HPLC method was employed to detect...

The use of plant parts (leaves, flowers, stems, barks, roots etc.) in traditional medicine is increasingly gaining ground modern medicine, as sources have long been recognized secondary metabolites which can be used to treat a wide range diseases. effect extracts Justicia secunda leaves on red blood cells (RBC) count and haemoglobin (Hb) concentration was investigated adult Sprague-Dawley rats establish haematinic activity. Phenylhydrazine (PHZ)-induced anaemic were treated with water,...

Hoslundia opposita is an important herb of ethnomedical importance in Ghana. Infusions the leaves are widely used traditional medicine as a purgative, diuretic, febrifuge, antibiotic, and antiseptic. The plant known to have antibacterial, antifungal antiviral activities. Due commercialisation this herb, there need develop standardization parameters for authentication quality control opposita. macromorphological, qualitative quantitative features, physicochemical phytochemical features...

Abstract Buruli ulcer is a devastating skin infection caused by Mycobacterium ulcerans . It endemic in the Amansie West district of Ashanti region Ghana where patients rely mainly on herbal preparations from practitioners. This work aimed at validating some employed traditional healers for management ulcer. Four preparations, obtained practitioners four communities were tested against clinical M. strain (NM203) using resazurin microplate assay. Cytotoxicity test was done extracts Chang liver...

Justiciaflava (Acanthaceae) is utilized in folk medicine for treating malaria, inflammatory conditions, and respiratory infections. In this study, the antiplasmodial anti-inflammatory activities of 70% hydroalcoholic leaf extract J. flava (JFE) were investigated. The activity was assessed by suppressive test Rane’s curative test. carrageenan-induced paw oedema assay chicks used to assess activity. test, JFE significantly suppressed parasitaemia level ( <math...

Background: Vitex doniana Sweet fruit, an under-utilised crop specie of Ghana, has not been validated for its ethnomedical use in managing inflammatory conditions. Therefore, the study sought to investigate anti-inflammatory and antioxidant activities as well isolate quantify one active constituents.Methods: In-vivo assay was done using carrageenan- induced oedema model chicks. The in-vitro property also investigated 2, 2-diphenyl-1-picrylhydrayl radical scavenging assay. acute subacute...