A5100385975- Molecular Sensors and Ion Detection
- Luminescence and Fluorescent Materials
- Photochromic and Fluorescence Chemistry
- Sulfur Compounds in Biology
- Nanoplatforms for cancer theranostics
- Supramolecular Self-Assembly in Materials
- Redox biology and oxidative stress
- Lipoproteins and Cardiovascular Health
- Genomics, phytochemicals, and oxidative stress
- Nitric Oxide and Endothelin Effects
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Organic Light-Emitting Diodes Research
- Carbon and Quantum Dots Applications
- Selenium in Biological Systems
- Diabetes Treatment and Management
- Metal-Organic Frameworks: Synthesis and Applications
- Analytical Chemistry and Sensors
- Polydiacetylene-based materials and applications
- Cancer, Lipids, and Metabolism
- Trace Elements in Health
- Plant-derived Lignans Synthesis and Bioactivity
- Polyoxometalates: Synthesis and Applications
- Photoreceptor and optogenetics research
- Synthesis and Properties of Aromatic Compounds
- Pregnancy and Medication Impact
Hunan University of Science and Technology
2018-2024
Shenzhen University
2024
Zhengzhou People's Hospital
2015-2023
First Affiliated Hospital of Henan University
2023
Taiyuan University of Science and Technology
2020-2023
Pingdingshan University
2020-2021
Beijing Institute of Technology
2016-2020
Tongji University
2020
Southwest University
2018-2020
Taiyuan Institute of Technology
2020
Abstract Photoswitchable fluorescent polymers (PFPs) are emerging as a class of promising systems for photowritable pattern, optical anti‐counterfeiting, and information encryption. They typically use harmful UV light the stimulus, which often leads to inevitable photobleaching poor reversibility. To address this issue, visible‐light‐driven PFPs by copolymerization novel negative photochromic spiropyran monomer methyl acrylate developed. The obtained copolymers display bright red...
Imaging of hepatocellular nitric oxide (NO) in vivo is great importance for understanding its roles liver diseases, but such an imaging approach still lacking. Herein, a hepatocyte-targeting fluorescent NO sensor has been fabricated. This exhibits good water solubility, excellent selectivity, and high sensitivity (∼1.62 nM). The cells experiments reveal that Gal-RhB facilitates the visualization both HepG2 zebrafish. These results demonstrate may be promising tool studying function...
The endoplasmic reticulum (ER) has a central role in the fine-tuning of environmental and internal stimuli. We herein report ratiometric fluorescent probe, α-Naph, capable determining basal H2O2 ER. probe specifically responds to H2O2. limit detection is as low 38 nM, making it feasible sensor image intracellular In addition, utilizing its property, we are able measure concentration ER quantitatively, eliminating error caused by environment. calculated be 0.692 μM under normal conditions...
The control of the emission properties doping materials through molecular design makes organic potentially promising candidates for many optoelectronic applications and devices. However, systems with high quantum yields persistent luminescence processes have rarely been reported, their mechanisms are still not well established. Here we developed a series purely heavy-atom-free systems. guest molecules can dope either donor or acceptor matrixes, both leading to an enhanced fluorescence (Φ =...
Abstract Time‐resolved photofluorochromism constitutes a powerful approach to enhance information encryption security but remains challenging. Herein, we report strategy of using hydrogen bonds regulate the time for initiating photofluorochromism. In our strategy, copolymers containing negative photochromic spiropyran (NSP), naphthalimide, and multiple hydrogen‐bonding (UPy) units are designed, which display photo‐switchable fluorescence resonance energy transfer (FRET) process from...
Cadmium, a highly toxic environmental pollutant, is reported to induce toxicity and apoptosis in multiple organs cells, all possibly contributing certain pathophysiologic situations. Previous studies have described that cadmium induces biochemical physiological changes the heart finally leads cardiac dysfunctions, such as decreasing contractile tension, rate of tension development, rate, coronary flow atrioventricular node conductivity. Although many progresses been made, mechanism...
Photoswitchable fluorescent materials are desirable for many applications because their emission signals can be easily modulated on demand. In this study, novel photoswitchable multistate supramolecular polymers (PMFSPs) were prepared via host-guest interactions under a facile ultrasonication strategy. the system, photochromic diarylethylene monomer (SDTE, donor) and adamantane-containing (BAC) covalently combined into backbone of guest polymer (P1) radical copolymerization. Meanwhile, host...
Photoswitchable supramolecular fluorescent polymers (PSFPs) were prepared that can adaptively change their fluorescence between none, green and red by the irradiation of different light. PSFPs successfully applied in underwater data encryption anti-counterfeiting labels.
Dual host–guest interaction-mediated photoswitchable fluorescent supramolecular polymers can flexibly regulate the optical performance and successfully applied in information encryption anti-counterfeiting label.
Cellular self-regulation of reactive oxygen species (ROS) stress via glutathione (GSH) antioxidant repair plays a crucial role in maintaining redox balance, which affects various physiological and pathological pathways. In this work, we developed simple yet effective strategy for reversible, dynamic, real-time fluorescence imaging ROS GSH repair, based on novel Ge-pyronine dyes (GePs). Unlike the current O-pyronine (OP) dye, GePs can be quenched reduction then greatly restored by (e.g.,...
The detection of mitochondrial formaldehyde (FA) is great significance because FA generated through a one-carbon cycle in mitochondria, and abnormal elevations levels can damage mitochondria by decreasing the membrane potential inhibiting respiration. Herein, mitochondria-targetable two-photon probe (Mito-FA-FP) has been well demonstrated. Mito-FA-FP conjugated with hydrazine as FA-reactive site pyridine derivate moiety. After reacting FA, exhibits dramatic fluorescence enhancement (12-fold)...
A ratiometric method for tracing the variation of selenocysteine (Sec) in a cell matrix was provided. This constructed by quantitative correlation between fluorescence ratio of<bold>Rat-Sec</bold>(blue emission, probe) and<bold>Nap-OH</bold>(green-yellow product from Sec-specific reaction) and concentration Sec.
Through rational design, in vivo supramolecular construction of nanodrugs could precisely proceed the lesion areas, which may apparently improve theranostic performance nanomaterials. Herein, a tumor microenvironment-responsive nanoplatform (Ce6-GA@MnO2-HA-PEG) has been constructed to achieve and enhance therapeutic efficacy combined phototherapy through intracellular reassembly. Under microenvironment, such undergo process decomposition–reassembly form situ photothermal assemblies. The...