A5100742283- Genomics, phytochemicals, and oxidative stress
- Natural product bioactivities and synthesis
- Antioxidant Activity and Oxidative Stress
- Phytochemicals and Antioxidant Activities
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Fungal Biology and Applications
- Curcumin's Biomedical Applications
- Retinoids in leukemia and cellular processes
- Skin Protection and Aging
- Epigenetics and DNA Methylation
- Drug-Induced Hepatotoxicity and Protection
- Polysaccharides and Plant Cell Walls
- Cardiac Fibrosis and Remodeling
- MicroRNA in disease regulation
- Atmospheric chemistry and aerosols
- Diet and metabolism studies
- Cardiac electrophysiology and arrhythmias
- Pharmacological Effects of Medicinal Plants
- Plant-derived Lignans Synthesis and Bioactivity
- Atmospheric Ozone and Climate
- Extracellular vesicles in disease
- Seed and Plant Biochemistry
- Infant Nutrition and Health
- Atmospheric and Environmental Gas Dynamics
Rutgers, The State University of New Jersey
2017-2024
Jinan University
2024
First Affiliated Hospital of Nanchang University
2015-2022
First Affiliated Hospital of Wenzhou Medical University
2022
Nanchang University
2015-2022
Second Hospital of Anhui Medical University
2022
Anhui Medical University
2022
Wenzhou Medical University
2022
Rutgers Sexual and Reproductive Health and Rights
2020
Gorgias Press (United States)
2020
Inflammation is highly associated with colon carcinogenesis. Epigenetic mechanisms could play an important role in the initiation and progression of cancer. Curcumin, a dietary phytochemical, shows promising effects suppressing colitis-associated cancer azoxymethane-dextran sulfate sodium (AOM-DSS) mice. However, potential epigenetic curcumin remain unknown. In this study, anticancer effect 18-week AOM-DSS mouse model was confirmed. We identified lists differentially expressed methylated...
Eleven grape cultivars were analysed to explore the variety differences of fresh phenolic profiles. The results showed that free phenolics predominant in skins and pulps, higher antioxidant activities than bound. In 11 cultivars, Muscat Kyoho extracts had highest total content (10.525 mg GAE g−1 FW) pulps (1.134 FW), exhibited DPPH radical scavening capacity (EC50=11.7 μg mL−1) oxygen absorbance (ORAC) value (190.57 μmol TE skin. addition, most abundant found be flavonoids such as kaempferol...
Steam explosion (SE) is an efficient technology to disrupt materials for improving their quality.
Abstract Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental carcinogens accountable to developing skin cancers. Recently, we reported that exposure benzo[a]pyrene (B[a]P), a common PAH, causes epigenetic and metabolic alterations in the initiation, promotion progression of non-melanoma cancer (NMSC). As follow-up investigation, this study examines how dietary triterpenoid ursolic acid (UA) regulates B[a]P-driven pathways SKH-1 hairless mice. Our results show UA intercepts...
This study investigated the effect of anthocyanin extracts from purple-fleshed sweet potato (PSP-AE) on ultraviolet B (UVB)-induced skin photoaging in BALB/c-nu mice. UPLC-QTOF-MS analysis showed six compounds were identified PSP-AE. Administration PSP-AE ameliorated UVB-irradiated macroscopic and histopathological lesions via suppressing epidermal hyperplasia collagen degradation, while improving content moisture hydroxyproline. Additionally, inhibited UVB-induced oxidative stress increased...
Acute lung injury (ALI) is the primary cause of death among patients with acute paraquat (PQ) poisoning, whereby peroxidative damage an important mechanism underlying PQ-induced injury. There a lack effective interventional drugs for PQ poisoning. Oxaloacetic acid (OAA) participates in multiple vivo metabolic processes, it facilitates clearance reactive oxygen species (ROS) and improves mitochondrial function. The study aimed to assess protective effects OAA on ALI elucidate molecular...
The bioactive activities, composition and concentration of phenolics extracted from tartary buckwheat bran were evaluated.
Introducing complementary foods is critical for promoting infant health and development.
Astaxanthin (AST) is a well-known carotenoid with high antioxidant capacity. This study was designed to evaluate the nutritional and metabolic effects of microalgal AST added diets broiler chicks under heat stress. A total 240 Cornish male (1 day old) were divided into six cages per treatment (eight cage) fed corn–soybean meal diet supplemented from Haematococcus pluvialis at 0, 10, 20, 40, 80 mg/kg for 6 weeks. Heat stress employed during weeks 4–6. The supplementation led dose-dependent...
Abstract Nonmelanoma skin cancers (NMSCs) are the most common type of cancers. Major risk factors for NMSCs include exposure to ultraviolet (UV) irradiation. Ursolic acid (UA) is a natural triterpenoid enriched in blueberries and herbal medicinal products, possess anticancer activities. This study focuses on impact UA epigenomic, genomic mechanisms prevention UVB‐mediated NMSC. CpG methylome RNA transcriptome alterations early, promotion late stages treated UVB‐induced NMSC SKH‐1 hairless...