Short chain fatty acids (SCFAs) are known to be actively involved in multiple brain disorders, but their roles sepsis-associated encephalopathy (SAE) remain unclear. Here, we investigated the neuroprotective effects of SCFAs on SAE mice. Male C57BL/6 mice were intragastrically pretreated with for seven successive days, and then subjected induced by cecal ligation puncture. The behavioral impairment, neuronal degeneration, levels inflammatory cytokines assessed. expressions tight junction...

In this paper, multi-source observation, such as aircraft, ground-based remote sensing, and satellite-retrieved data, has been utilized to compare analyze the vertical characteristics of aerosol optical properties planetary boundary layer height (HPBL) over North China Plain (NCP) region during May–June 2016. Aircraft observations show profiles absorption coefficients (σabs), scattering (σsca), extinction (σext) gradually decrease with altitude, their maximum values near HPBL. The σext...

Acute lung injury (ALI) is the primary cause of death among patients with acute paraquat (PQ) poisoning, whereby peroxidative damage an important mechanism underlying PQ-induced injury. There a lack effective interventional drugs for PQ poisoning. Oxaloacetic acid (OAA) participates in multiple vivo metabolic processes, it facilitates clearance reactive oxygen species (ROS) and improves mitochondrial function. The study aimed to assess protective effects OAA on ALI elucidate molecular...

Introduction: Sepsis is a severe life-threatening infection that induces series of dysregulated physiologic responses and results in organ dysfunction. Acute lung injury (ALI), the primary cause respiratory failure brought on by sepsis, does not have specific therapy. Protopine (PTP) an alkaloid with antiinflammatory antioxidant properties. However, function PTP septic ALI has yet been documented. This work sought to investigate how affected mechanisms involved damage, including...

Strong light–matter coupling has shown great potential for modifying the electrooptical properties of semiconducting materials in recent years. In strong regime, excitons and cavity photons form new states named exciton-polaritons, with their being a hybrid each constituent. Herein, we report observed solution-processed donor:acceptor bulk-heterojunction organic solar cells (OSCs) evidenced by Rabi-splitting ∼300 meV effects on OSC operations. Combining transient photovoltage decay...

Acute lung injury (ALI) induced by paraquat (PQ) progresses rapidly, leading to high mortality; however, there is no specific antidote. Our limited knowledge of the pathogenic toxicological mechanisms PQ has hindered development treatments against exposure.Pyroptosis a form programmed cell death recently identified as novel molecular mechanism adopted chemotherapeutic drugs for cancer therapy. However, involvement pyroptosis in PQ-induced not been reported. Therefore, we investigated effects...

Paraquat (PQ) intoxication causes thousands of mortalities every year, worldwide. Its pulmonary-targeted accumulation and the acute lung injury it subsequently causes, remain a challenge for detoxification treatment. A previous study has demonstrated that upregulation nuclear factor erythroid-2 related 2 (Nrf2) prevents PQ toxicity in cell line murine models. As Nrf2 target genes include group membrane transporters, current assessed protective mechanism exerted by against intracellular via...

Excessive inflammation and increased apoptosis of macrophages contribute to organ damage poor prognosis sepsis. Ginkgolic acid (GA) is a natural constituent extracted from the leaves Ginkgo biloba, that can regulate apoptosis. The present study aims investigate potential effect GA in treating sepsis its possible mechanisms.Here, classic septic mice model lipopolysaccharide (LPS)-induced RAW 264.7 were established. Cytokines serum culture supernatant detected by ELISA, mRNA levels them...

Robust water management is in intense demand many scarcity areas, such as arid and semi-arid regions the world. As part of regional strategy, rain enhancement vital to replenish groundwater reservoirs, key challenge how assess its effectiveness. Some recent weather modification experiments attained cloud seeding effect through advanced situ measurement coupled with accurate numerical simulation. However, there still a lack an objective scientific approach quantitatively evaluate effect,...

The FAO56 Penman–Monteith model (FAO56-PM) is widely used for estimating reference crop evapotranspiration (ET0). However, key variables such as shortwave radiation (Rs) and net longwave (Rln) are often unavailable at most weather stations. While previous studies have focused on calibrating Rs, the influence of large Rln, particularly in high-altitude regions with thin air, remains unexplored. This study investigates this issue by using observed data from Bange central Tibet to identify...

Complete blood count (CBC) is one of the most extensively used tests in clinical practice. In order to determine diagnostic value CBC paraquat (PQ) and organophosphorus (OPPs) poisoning, indices PQ- OPPs-poisoned patients were investigated this study. A total 96 PQ poisoning patients, 90 OPPs 188 healthy subjects included The divided into different groups according their symptoms. All analyzed by Fisher discriminant, partial least-squares discriminant analysis (PLS-DA), variance analysis,...

While the efficiency of organic solar cells (OSCs) has increased considerably in recent years, there remains a significant gap between experimental open‐circuit voltage ( V OC ) and theoretical limit. Understanding origin this energy loss is important for future development OSCs, with temperature‐dependent measurement an approach to help unlock underlying physics. Interestingly, previous studies have observed reduction at low temperature that been attributed by different phenomena. To...

With the rapid development of digital technology in China, Digital Inclusive Finance, which uses financial services to promote inclusion, is developing rapidly. This paper Peking University Financial Inclusion index China and Family Panel Studies (CFPS) data construct a predictive model using LightGBM machine learning algorithm study whether Finance can predict household wealth analyze characteristics strong ability for wealth. They found that: (1) introduction improve prediction performance...

Paraquat (PQ) has caused countless deaths throughout the world. There remains no effective treatment for PQ poisoning. Here we study blood metabolome of PQ-poisoned patients using ultraperformance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry (UPLC/Q-TOF MS). Patients were divided into groups according concentration. Healthy subjects served as controls. Metabolic features statistically analyzed multivariate pattern-recognition techniques identify most important...

In this study, the impact of artificial precipitation enhancement operation on wet scavenging air pollutants is investigated based an aircraft in Yangtze River Delta region China 1 November 2020. Multiple measurement data are used, including regional meteorological and environmental comprehensive field observation at Nanjing University Information Science Technology (NUIST) campus site. The results show that affected areas cover part Anhui Jiangsu provinces. ratio between target contrast...

This paper investigates the issue of advertisement implantation in virtual reality (VR) video for potential consumer electronics applications. Unlike traditional implantation, VR faces new challenges as it needs to consider both user immersion and attention. In this paper, we propose a deep neural network called SISAd identify candidate spaces scenes. Particularly, combine instance segmentation saliency detection techniques automatically detect locate regions that attract users' visual...

Download This Paper Open PDF in Browser Add to My Library Share: Permalink Using these links will ensure access this page indefinitely Copy URL DOI

The Critical Role of Temperature-dependent Mobilities in Determining the Open-Circuit Voltage Bulk-heterojunction Organic Solar CellsYahui Tang a, ba Department Materials Science and Engineering, Monash University, Clayton, Victoria, 3800 Australia, Wellington Rd, Australiab School Chemistry, University Sydney, NSW 2006, AstraliaProceedings Device Physics Characterization Interpretation Perovskite (DEPERO)València, Spain, 2023 October 3rd - 5thOrganizers: Sandheep Ravishankar, Juan Bisquert...