A5034327727- Advanced Fiber Optic Sensors
- Autophagy in Disease and Therapy
- Immune cells in cancer
- Phagocytosis and Immune Regulation
- Pharmacological Effects of Natural Compounds
- Ion Channels and Receptors
- Underwater Vehicles and Communication Systems
- Seismic Waves and Analysis
- Geophysics and Sensor Technology
- Natural Compounds in Disease Treatment
- Ginkgo biloba and Cashew Applications
- Underwater Acoustics Research
Wenzhou Medical University
2021-2023
First Affiliated Hospital of Wenzhou Medical University
2021-2023
Jilin University
2021
A high-sensitivity ultralow-frequency fiber optic interferometric seismometer using phase feedback control is proposed and demonstrated. The principle of sensitivity improvement described, the characteristics seismometer, including vibration sensing with Michelson interferometer without control, are analyzed in terms amplitude response response. loop designed implemented, higher for very low frequency achieved. efficacy new approach demonstrated experimentally, showing that weak signal...
A high-performance fiber optic interferometric hydrophone based on a push-pull mandrel structure, with high sensitivity and wide-frequency response, is designed developed. Each arm of the Michelson interferometer coil wrapped onto separate but concentric thin elastic tube as sensing to detect acoustic pressure wave. The fabricated examined experimentally, demonstrating its capacity very low-frequency underwater variation. theoretical design validated results showing that has an average...
Excessive inflammation and increased apoptosis of macrophages contribute to organ damage poor prognosis sepsis. Ginkgolic acid (GA) is a natural constituent extracted from the leaves Ginkgo biloba, that can regulate apoptosis. The present study aims investigate potential effect GA in treating sepsis its possible mechanisms.Here, classic septic mice model lipopolysaccharide (LPS)-induced RAW 264.7 were established. Cytokines serum culture supernatant detected by ELISA, mRNA levels them...
Immune paralysis induced by sepsis, especially dysfunction of CD4+ T cells, leads to an increased risk infection. In abnormal differentiation lymphocytes is associated with multiorgan syndrome. lymphocytes, the Orai1/nuclear factor activated Cells (NFAT) pathway a critical mediator infection, inflammation, and autoimmunity. this study, we confirmed immunosuppression splenic cells in septic mice. Furthermore, found that Orai1/NFAT signaling was inhibited mice; however, overexpression Orai1...
Abstract Although the Pink1/Parkin-mediated mitophagy is closely related to inflammation and immunoregulation, its effect on apoptosis of splenic dendritic cells (DCs) in sepsis remains unknown. Here, our current study demonstrates that enhanced, DCs increased during Wild Type (WT) mice. It also shows occurs process sepsis-induced DCs. Moreover, level Pink1-knockout (Pink1-KO) mice lower than WT mice, while Pink1-KO further more sepsis. The mitochondrial dysfunction aggravated sepsis, which...