A5015045452- Insect Resistance and Genetics
- Insect-Plant Interactions and Control
- Insect behavior and control techniques
- Biofuel production and bioconversion
- Advanced Algorithms and Applications
- Insect Pest Control Strategies
- Bioenergy crop production and management
- Cholinesterase and Neurodegenerative Diseases
- Nitrogen and Sulfur Effects on Brassica
- Anaerobic Digestion and Biogas Production
- Insect symbiosis and bacterial influences
- Insect and Pesticide Research
- Nuclear Receptors and Signaling
- Cardiovascular Disease and Adiposity
- CRISPR and Genetic Engineering
- Atrial Fibrillation Management and Outcomes
- Peptidase Inhibition and Analysis
- Genetically Modified Organisms Research
- Pharmacological Effects of Natural Compounds
- Bone fractures and treatments
- Natural product bioactivities and synthesis
- Plant biochemistry and biosynthesis
- Bone health and osteoporosis research
- Enzyme Production and Characterization
- Orthopaedic implants and arthroplasty
China Agricultural University
2024
Fujian Agriculture and Forestry University
2020-2022
Ministry of Agriculture and Rural Affairs
2022
Hubei University of Chinese Medicine
2012
In many organisms, cytochrome P450 enzymes are the primary detoxifying enzymes. Enhanced activity can be mediated by emergence of new genes, increased transcription due to mutations in promoter regions, changes enzyme structures and functions protein-coding or post-translational modifications; all these subject insecticide selection pressure. Multiple signalling pathways key effector molecules involved regulation insect P450s. Increased is a mechanism inducing resistance. Hence,...
The leaves of Ilex kudingcha are used as an ethnomedicine in the treatment symptoms related with diabetes mellitus and obesity throughout centuries China. present study investigated antidiabetic activities active components group (ACG) obtained from alloxan-induced type 2 diabetic mice. ACG significantly reduced elevated levels serum glycaemic lipids 3-Hydroxy-3-methylglutaryl coenzyme A reductase glucokinase were upregulated significantly, while fatty acid synthetase, glucose-6-phosphatase...
To investigate the connection between atrial fibrillation (AF) and miR-138-5p to further explore possible mechanism.MiR-138-5p expression of right appendage (RAA) tissues in 28 patients with AF 22 sinus rhythm (SR) was detected by quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR). Moreover, cell proliferation assay conducted AC16 cells which were transfected inhibitors or mimics. Furthermore, Western blot assay, luciferase RNA immunoprecipitation performed uncover...
The diamondback moth, Plutella xylostella, is a lepidopteran insect that mainly harms cruciferous vegetables, with strong resistance to variety of agrochemicals, including Bacillus thuringiensis (Bt) toxins. This study intended screen genes associated Bt in P. xylostella by comparing the midgut transcriptome Cry1Ac-susceptible and -resistant strains together two toxin-treated 24 h before sampling. A total 12 samples were analyzed BGISEQ-500, each sample obtained an average 6.35 Gb data....
The CRISPR/Cas9 system is an efficient tool for reverse genetics validation, and the application of this in cell lines provides a new perspective on target gene analysis development biotechnology tools. However, diamondback moth, Plutella xylostella, integrity utilization still need to be improved ensure system. Here, we stabilize transfection efficiency P. xylostella at different passages about 60% by trying reagents adjusting method. For Cas9 expression CRIPSPR/Cas9 system, identified...
Methionine aminopeptidases (MetAPs) catalyze the cleavage of N-terminal initiator methionine (iMet) in new peptide chains and arylamides, which is essential for protein synthesis. MetAP differentially expressed two diamondback moth (DBM; Plutella xylostella) strains: G88 susceptible strain Cry1S1000 strain, are resistant to Bt toxin Cry1Ac, implicating that expression might be associated with resistance. In this study, we identified cloned a gene from DBMs, named PxMetAP1, has CDS 1140 bp...
The oriental fruit fly,