A5024675265- Nuclear Physics and Applications
- Boron Compounds in Chemistry
- Radiation Therapy and Dosimetry
- Radiation Detection and Scintillator Technologies
- Atomic and Subatomic Physics Research
- Particle accelerators and beam dynamics
- Radiation Effects and Dosimetry
- Graphite, nuclear technology, radiation studies
- Nuclear reactor physics and engineering
- Fusion materials and technologies
- Ion-surface interactions and analysis
- Particle Detector Development and Performance
- Magnetic confinement fusion research
- Spacecraft and Cryogenic Technologies
- Laser-Plasma Interactions and Diagnostics
- Dark Matter and Cosmic Phenomena
- Integrated Circuits and Semiconductor Failure Analysis
- Radiopharmaceutical Chemistry and Applications
- Muon and positron interactions and applications
- Pulsed Power Technology Applications
- Medical Imaging Techniques and Applications
- X-ray Spectroscopy and Fluorescence Analysis
- Nuclear physics research studies
- Engineering Technology and Methodologies
- Particle Accelerators and Free-Electron Lasers
Novosibirsk State University
2009-2022
Budker Institute of Nuclear Physics
2013-2022
Siberian Branch of the Russian Academy of Sciences
2011-2020
Russian Academy of Sciences
2009-2015
Institute of Microelectronics
2012
Novosibirsk State Technical University
2009
Polymer Research Institute
1989
Institute of Medical Polymers
1989
A compact accelerator-based neutron source has been proposed and created at the Budker Institute of Nuclear Physics in Novosibirsk, Russia. An original design tandem accelerator is used to provide a proton beam. The beam energy can be varied within range 0.6-2.3 MeV, keeping high-energy stability 0.1%. current also wide (from 0.3 mA 10 mA) with high (0.4%). In device, flux generated as result
AbstractRecent results of the experiments at GOL-3 facility are presented. In present configuration device, plasma with a density 1014[divided by]1016 cm-3 is confined in 12-meter-long solenoid, which comprises 55 corrugation cells mirror ratio Bmax/Bmin=4.8/3.2 T. The solenoid heated up to 2-4 keV temperature by high power relativistic electron beam (˜1 MeV, ˜30 kA, ˜8 μs, ˜120 kJ) injected through one ends. Mechanism experimentally observed fast ion heating, issues stability and...
AbstractThe paper reviews recent experimental results from GOL-3. Currently efforts are focused on further development of a physical database for multiple-mirror confinement systems and also an upgrade plasma heating GOL-3 device.In general, current parameters demonstrate good prospects trap as fusion reactor.
A vacuum-insulated tandem accelerator was used to observe in situ blistering during 2-MeV proton irradiation of metallic samples a fluence up 6.7 × 1020 cm−2. Samples consisting copper different purity, tantalum and tantalum-copper compounds were placed on the beam path forced cool. The surface state observed using charge-coupled device camera with remote microscope. Thermistors, pyrometer an infrared applied measure temperature irradiation. After irradiation, analyzed X-ray diffractometer,...
Boron carbide has been proposed for the neutron protection of equipment in ITER diagnostic ports and reducing dose to maintenance personnel. The chemical composition, vacuum, thermal properties ceramics boron were studied. It is demonstrated that outgassing rate meets requirements Vacuum Handbook. Calculation total gas emission from equatorial port #11 carried out. contact conductivity at boundary between bronze measured. Manganese content determined by method activation analysis ceramics....
A compact accelerator-based neutron source has been proposed and created at the Budker Institute of Nuclear Physics in Novosibirsk, Russia. An original design tandem accelerator is used to provide a proton beam. The flux generated as result 7Li(p,n)7Be threshold reaction using solid lithium target. beam shaping assembly applied convert this into epithermal neutrons with characteristics suitable for BNCT. BNCT technique being tested vitro vivo studies, dosimetry methods are developed....
Boron neutron capture therapy (BNCT) is an anticancer modality realized through 10B accumulation in tumor cells, irradiation of the tumor, and decay boron atoms with release alpha-particles lithium nuclei that damage cell DNA. As high-LET particle takes place inside cells absorbed dose calculations are difficult, since no essential extracellular energy emitted. We placed gold nanoparticles saturated to more accurately measure dose. T98G accumulated ~50 nm (AuNPs, 50 µg gold/mL)...
The accelerator based epithermal neutron source for Boron Neutron Capture Therapy (BNCT) is proposed, created and used in the Budker Institute of Nuclear Physics. In 2014, with support Russian Science Foundation BNCT laboratory purpose to end 2016 get flux, suitable BNCT. For getting 3 mA 2.3 MeV proton beam, was a new type - tandem vacuum isolation. On this moment, we have stationary beam current 1.75 mA. Generation neutrons carried out by dropping on lithium target as result threshold...
A source of epithermal neutrons based on a tandem accelerator with vacuum insulation for boron neutron capture therapy malignant tumors was proposed and constructed. Stationary proton beam 2 MeV energy, 1.6 mA current, 0.1% energy monochromaticity 0.5% current stability has just been obtained.
A vacuum insulated tandem accelerator was used to study the effect of blistering on neutron yield under 2-MeV proton bombardment lithium target. The target is a thin layer evaporated onto an efficiently cooled copper substrate. Targets with thickness from 1 84 µm were irradiated by protons up fluence 6.3 1020 cm−2 which significantly greater than threshold. state targets surface observed using long-distance microscope, video camera, infrared camera. dose measured dosimeters, flux density...
In this study, we present results of initial trials a scintillator-over-fiber detector system with silicon photomultiplier readout designed at Budker Institute Nuclear Physics. The demonstrate that the proposed system, using pair boron-enriched and boron-free scintillators, could be successfully used for monitoring thermal neutron flux estimation irradiation dose. Nevertheless, it is necessary to optimize design head components ensure long time stability heavy radiation background.
This work describes a new method for in situ measuring the lithium layer thickness. The is based on registration of yield 478 keV gamma-quanta 7 Li(p,p'γ) Li reaction. results radial distribution thickness thermally deposited vacuum cooled copper substrate are presented. possibility using this certification targets used boron neutron capture therapy noted.
In the construction of a tandem accelerator with vacuum insulation several changes were made. This allowed us to suppress unwanted flow charged particles in accelerator, improve its high-voltage stability, and increase proton beam current from 1.6 mA 5 mA.
Objective : to investigate the impact of a neutron beam formed with accelerator-based epithermal source designed at G.I. Budker Institute Nuclear Physics (INP) on viability human and animal tumor cells cultured in presence boron-10 isotope. Material methods. Human U251 T98G glioma Chinese hamster CHO-K1 V-79 were incubated various concentrations culture medium containing 10B-enriched L-boronophenylalanine. The irradiated neuron using source. A clonogenic assay was used evaluate cells....