A5078290415- Agricultural and Food Sciences
- Phytochemistry Medicinal Plant Applications
- Phytochemicals and Antioxidant Activities
- Essential Oils and Antimicrobial Activity
- Advancements in Transdermal Drug Delivery
- Dermatology and Skin Diseases
- Natural product bioactivities and synthesis
- Bee Products Chemical Analysis
- Advanced Drug Delivery Systems
- Plant biochemistry and biosynthesis
- Fatty Acid Research and Health
- Bioactive Compounds and Antitumor Agents
- Preterm Birth and Chorioamnionitis
- Environmental Sustainability and Education
- Long-Term Effects of COVID-19
- Meat and Animal Product Quality
- Computational Drug Discovery Methods
- Phytochemistry and Bioactive Compounds
- Healthcare Regulation
- Spectroscopy and Chemometric Analyses
- Acne and Rosacea Treatments and Effects
- Moringa oleifera research and applications
- Analytical Chemistry and Chromatography
- Postharvest Quality and Shelf Life Management
- Pregnancy and Medication Impact
Universidade Federal do Rio Grande do Sul
2019-2024
Universidade Norte do Paraná
2023
Universidade do Vale do Rio dos Sinos
2020-2021
Universidade Federal do Rio Grande
2020
Sesquiterpene compounds are applied as permeation promoters in topical formulations. However, studies exploring their impact on nanostructured systems, changes profile, and consequently, its biological activity restricted. This study aimed to investigate the correlation between skin of major sesquiterpenes, beta-caryophyllene, caryophyllene oxide from oleoresin Copaifera multijuga, after delivery into nanoemulgels, vivo antiedematogenic activity. First, ten nanoemulgels were prepared...
Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) widely used to treat rheumatoid arthritis and other inflammatory diseases. Normally by oral route, this presents numerous side effects related administration such as nausea, dyspepsia, diarrhea, constipation even renal complications. To avoid that, topical of ketoprofen represents good alternative, since has both partition coefficient aqueous solubility suitable for skin application, compared NSAIDs. In study, we describe the...
The sesquiterpene β-caryophyllene, classified as a phytocannabinoid compound, has been widely studied owing to its multi-target action. In addition, this compound demonstrated application skin permeation promoter. context, study aimed evaluate the feasibility of associating β-caryophyllene and indomethacin in oily core hydrogel thickened nanoemulsions, well as, vivo anti-inflammatory effect association by croton oil ear edoema induced model. After topical application, nanoemulgels resulted...
Brunfelsia uniflora (Pohl) D. Don roots have been widely used in folk medicine for treating inflammatory conditions. However, few studies elucidated compounds that justify their traditional use. This study was conducted to characterize the phytochemical profile and evaluate vitro antioxidant capacity, vivo anti-inflammatory activity of extracts obtained from B. by comparing an herbal remedy (HR) with crude hydroalcoholic extract (CHE). In analysis, scopoletin identified as marker compound....
Cissus verticillata and Sphagneticola trilobata have been used in Brazilian folk medicine for Diabetes Mellitus treatment, although their pharmacological toxicological profile has not clearly established. Thus, the aim of this study was to evaluate preclinical toxicity aqueous extracts C. S. trilobata. The main groups secondary metabolites were investigated, species differed by presence coumarins tannins extracts. highest contents phenolic compounds flavonoids quantified infusion with 2.594...
Fosamprenavir calcium is a protease inhibitor widely used in the treatment and prevention of human immunodeficiency virus acquired syndrome. This serves as prodrug amprenavir, offering better oral bioavailability. Although this drug was approved by FDA 2003, there are few methods established for quantifying stability quality control analysis fosamprenavir-coated tablets. The purpose study to develop validate method determining tablets (Telzir®) that may be applied any laboratory....
Syzygium cumini fruit is rich in anthocyanins and antioxidant compounds such as vitamin C, making it interesting for the extraction of natural dyes. In this study, an optimized Box–Behken Design method was proposed extracting organic solvent-free dye from S. cumini. The obtained stabilized by freeze-drying, intense purple powder high anthocyanins, especially delphinidin-3,5-diglucoside cyanidin-3,5-diglucoside, phenolic compounds. Moreover, dye’s preliminary safety profile confirmed using...
Este breve estudo foi desenvolvido com o intuito de abrir uma discussão acerca da formação professores indígenas que fazem parte sociedade Xavante, tendo em vista as suas indigências Educacionais e os indivíduos desta comunidade, quais deixam aldeias a procura escolas situadas Mato Grosso, Brasil. Citar-se-á, curso Letras, ofertado pela Universidade Federal qual, na opinião dos autores deste estudo, não oferta contemple tal público, contudo, sabe-se problema se encosta no próprio curso, ou...
Introduction: In late 2019, the coronavirus disease (COVID-19) emerged in Wuhan, China. COVID-19 was characterized March 2020 as a pandemic and has already caused million deaths worldwide. Studies help clarify clinical profile of this disease, repeatedly showing that presence morbidities such type 2 diabetes mellitus (DM2) its associated diseases (obesity, hypertension, cardiovascular disease) are important risk factors for severity prognosis addition to advanced age. Therefore, study aimed...