A5100763115- Wound Healing and Treatments
- Skin Protection and Aging
- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- melanin and skin pigmentation
- Immune Response and Inflammation
- Ginkgo biloba and Cashew Applications
- CAR-T cell therapy research
- Mesenchymal stem cell research
- Biochemical Analysis and Sensing Techniques
- Phytochemical and Pharmacological Studies
- Pharmacological Effects of Medicinal Plants
- Vitamin K Research Studies
- Phytochemistry and Bioactive Compounds
- Tissue Engineering and Regenerative Medicine
- Laser Applications in Dentistry and Medicine
- Antioxidant Activity and Oxidative Stress
- Bone Tumor Diagnosis and Treatments
- Medical and Biological Ozone Research
- Phytochemical compounds biological activities
- Histiocytic Disorders and Treatments
- Microbial Metabolism and Applications
- Marine Sponges and Natural Products
- Selenium in Biological Systems
- Pneumonia and Respiratory Infections
Incheon National University
2017-2021
International St. Mary's Hospital
2020-2021
Kyungsung University
2002-2015
United States Air Force Academy
2011
Pusan National University Hospital
2007
Yonsei University
1990-2003
Pusan National University
2002-2003
Pukyong National University
2002
Oklahoma Medical Research Foundation
2002
New York University
1999
The beneficial effects of adipose-derived stem cell conditioned medium (ADSC-CM) on skin regeneration have been reported. Although the mechanism how ADSC-CM promotes is unclear, contained various growth factors and it an excellent raw material for treatment. produced in a hypoxia condition ADSC—in other words, Advanced Adipose-Derived Stem Protein Extract (AAPE)—has great merits regeneration. In this study, human primary keratinocytes (HKs), which play fundamental roles tissue, was used to...
Id1 is an inhibitor of a group basic helix-loop-helix transcription factors, collectively called E proteins, which includes E12, E47, E2-2, and HEB. We have generated transgenic mice in specifically expressed T cells. The total number thymocytes these less than 4% that wild-type mice. majority the are CD4 CD8 double negative bear cell surface markers multipotent progenitor A small thymocytes, however, differentiate into or single-positive cells, also display different characteristics from...
For innate immune defense, lower animals such as fish and amphibian are covered with skin mucus, which acts both a mechanical biochemical barrier. Although several mucus sources have been isolated studied for their immunological functions, the precise mechanism(s) of action remains unknown. In present study, we additionally found eel (ESM) to be promising candidate use in anti-tumor therapy. Our results showed that viability K562 cells was decreased dose-dependent manner by treatment ESM....
Bioassay-guided fractionation of an organic extract the broth from marine-derived fungus culture Aspergillus parasiticus led to isolation and subsequent structural elucidation a new gabosine derivative, parasitenone (1), two known benzyl alcohols, 3-chloro-4,5-dihydroxybenzyl alcohol (2) gentisyl (3). The alcohols (2, 3) were identified as principal free radical scavenging components. Parasitenone (1) also showed moderate activity in assay.
Regulatory T (Treg) cells, a type of immune cell, play very important role in the response as subpopulation cells. In this study, we investigated effects Treg cells conditioned media (CM) on cell migration. Various cytokines and growth factors CM can effect re-epithelialization stage during wound healing.Isolated CD4+CD25+ from Peripheral Blood Mononuclear Cells (PBMCs) were cultured obtained. HaCaT keratinocytes treated with various concentration CM. Cell migration, proliferation expression...
KIM, SEONG-JANG M.D.; SEOK, JU-WON IN-JU YONG-KI JUNG, DAE-SOO DONG-SOO M.D. Author Information
Various vaccines were rapidly developed during the COVID-19 pandemic to prevent and treat infections but global continue, concerns about new mutations infectious diseases persist. Thus, active research focuses on developing, producing, supplying treatments for various potential pandemics.Natural killer(NK) cells, as innate immune can recognize eliminate abnormal cells like virus-infected cancer cells. Hence, their development anticancer antiviral is advancing. In this study, optimal...
목 적 : 폐구균은 중이염, 폐렴등의 흔한 원인이며 패혈증 및 뇌수막염 등 중증감염을 일으킬 수 있다. 최근 폐구균의 항균제 내성률이 증가하는 추세를 보이며, 예방접종이 개발되어 우리나라에서도 곧 시행될 전망이다. 이에 본 연구에서는 폐구균에 의한 질병분포 내성률에 대한 변화 등을 알아보고자 하였다. 방 법 1991년 1월부터 2000년 12월까지 연세대학교 신촌세브란스병원 소아과에서 시행한 배양검사상 폐구균이 확인된 환아 306명을 대상으로 임상양상과 진단명을 의무기록을 통해 후향적으로 조사하였고, 선천성 심질환이나 혈액종양질환을 앓고 있는 환아는 조사대상에서 제외하였다. 월별 빈도와 연도별 내성률의 연령에 따른 중증감염의 정도를 비교하였다. 결 과 1) 검사 당시 연령은 2개월부터 15세까지의 분포를 보이며 평균연령은 7.9세이었고, 연령별로는 6세 미만이 77%로 대부분을 차지하고 2세 42%이었다. 남녀 비는 1.6 1이었다. 2) 분포는 봄에 해당하는 3월과 4월이...
We adapted one of the in-vitro immunization methods to induce antibody responses and confirmed success by enzyme-linked immunosorbent assay (ELISA) without hybridization. have previously reported several using different conditioned media. Here we introduce another method a mixture three types supernatant (thymocytes, adherent non-adherent splenocytes mouse). Splenocytes were immunized recombinant human growth hormone (rhGH) with above media, results ELISA showed much higher optical density...
Matrix metalloproteinase-2 (MMP-2) is a key enzyme involved in tumor invasiveness. The plant of Magnolia officinalis Rehd. et Wils. often included as an ingredient various herbal remedies recommended for cancer theraphies Korea. Various extracts prepared from stems M. were tested cytotoxic activity on human hepatocellular carcinoma cell line, SK-Hep cells using the XTT assay method. Then, inhibitory effect was examined MMP-2 gelatin zymography. Methanol (MeOH) extract caused strongest...
The safety of pufferfish (Lagocephalus gloveri) liver oil and the contents some nutritional components were examined to obtain important information on their use as high valued functional foods. Pufferfish was extracted by hot-water method using <TEX>$1\%$</TEX> NaOH solution remove toxic compounds, then purified a general purifying fish oil. Any extraordinary clinical symptoms not observed from all groups administrated with throughout test period. None rats died when highest concentration...
Many researchers have described that mesenchymal stem cells conditioned medium and immune a clear whitening effect when they are used as cosmetic ingredients. In this study, we confirmed the efficacy of various concentrations cell media. The author tried to study has strong even with composition less than 20% (the most concentration in cosmetics). Because fact contains cytokines growth factors secreted by or cells, it is known effects such wound healing, antioxidant, effect. Recently, been...