A5024425523- Adrenal Hormones and Disorders
- Diabetes and associated disorders
- Pituitary Gland Disorders and Treatments
- Hormonal and reproductive studies
- Growth Hormone and Insulin-like Growth Factors
- Hormonal Regulation and Hypertension
- Cerebral Venous Sinus Thrombosis
- Diabetes Management and Research
- Parathyroid Disorders and Treatments
- Liver Disease Diagnosis and Treatment
- Genetic factors in colorectal cancer
- Epilepsy research and treatment
- Retinal Imaging and Analysis
- Vitamin D Research Studies
- Retinal Diseases and Treatments
- Myasthenia Gravis and Thymoma
- Glaucoma and retinal disorders
- Health Systems, Economic Evaluations, Quality of Life
- Inflammatory Biomarkers in Disease Prognosis
- Viral gastroenteritis research and epidemiology
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Thyroid Disorders and Treatments
- Chronic Lymphocytic Leukemia Research
- Digestive system and related health
- Genetics and Neurodevelopmental Disorders
Dr Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi
2020-2024
University of Health Sciences
2024
Üsküdar University
2024
Sağlık Bilimleri Üniversitesi
2021-2024
University of Health Science
2024
Istanbul Eye Hospital
2022-2023
Istanbul 29 Mayis University
2021
Bursa Uludağ Üni̇versi̇tesi̇
2019-2021
Pediatrics and Genetics
2019
Introduction: The aim of this study is to determine the coinfections with other respiratory pathogens in SARS-CoV-2 infected children patients a pediatric unit Istanbul.
 Methodology: This retrospective descriptive was conducted 1000-bedded tertiary education and research hospital Istanbul. All hospitalized diagnosis infection had been investigated for agents nasopharyngeal secretions. Laboratory confirmation were performed using reverse transcriptase-polymerase chain reaction...
We aimed to report the characteristics at admission, diagnosis, treatment, and follow-up of cases pediatric hyperprolactinemia in a large multicenter study.We reviewed records 233 hyperprolactinemic patients, under 18 years age, who were followed by different centers. The patients divided as having microadenomas, macroadenomas, drug-induced idiopathic hyperprolactinemia. Complaints their mode treatment (medication and/or surgery) outcomes evaluated detail.The mean age with was 14.5 years,...
Abstract Context There is a significant challenge of attributing specific diagnoses to patients with primary adrenal insufficiency unknown etiology other than congenital hyperplasia (non-CAH PAI). Specific per se may guide personalized treatment or illuminate pathophysiology. Objective This work aimed investigate the efficacy steroid hormone profiles and high-throughput sequencing methods in establishing non-CAH PAI origin. Methods Pediatric whose could not be established by clinical...
The increase in the prevalence of obesity, nonalcoholic fatty liver disease (NAFLD), and related comorbidities children creates a social financial burden. In our study, we aimed to evaluate findings together with anthropometric laboratory data twodimensional shear wave elastography (2D-SWE), one SWE types, which is noninvasive method for assessing tissue stiffness obtain quantitative that can be used early diagnosis follow-up.
The aim of this study was to evaluate the clinical characteristics, risk factors, treatment, and outcomes pediatric stroke cases. A total 118 patients diagnosed with arterial ischemic (AIS), hemorrhagic stroke, sinovenous thrombosis (SVT) between January 2000 December 2011 were included. Neonatal cases excluded. Demographic findings retrospectively examined from medical records. We identified stroke. age ranged 1 215 months (17.92 y), a mean 5.19±5.25 years. AIS accounted for majority (n=69,...
The concept of 'developmental and epileptic encephalopathy (DEE)' recognises that in infants presenting with severe early-onset epilepsy, neurodevelopmental comorbidity may be attributable to both the underlying cause adverse effects uncontrolled activity. There is no direct genotype - phenotype correlation DEEs. This study aimed report genetic phenotypic differences patients DEE.Genetic evaluations were performed due epilepsy combined developmental delay, encephalopathy, motor deficits,...
Neonatal diabetes mellitus (NDM) may be transient or permanent, and the majority is caused by genetic mutations. Early diagnosis essential to select patients who will respond oral treatment. In this investigation, we aimed present phenotype genotype of our with NDM share experience in a single tertiary centerA total 16 from 12 unrelated families are included study. The clinical presentation, age at diagnosis, perinatal family history, consanguinity, gender, hemoglobin A1c, C-peptide,...
What is already known on this topic? study adds?Monogenic diabetes a heterogeneous group of disorders, accounting for just 1-6% all diabetes.Variants in HNF1A, HNF4A, and GCK accounts most MODY-monogenic cases.Patient numbers information are limited less common causes monogenic forms diabetes.This the first Turkish multicenter genetic patients with molecularly diagnosed determined clinical laboratory features, admission characteristics distribution childhood.
The studies evaluating cases with type 1 diabetes mellitus (T1DM) and 2 (T2DM) in the adult population reported hyperreactive platelets increased activation of prothrombotic factors, resulting an risk thrombosis. aim this study was to evaluate effects poor glycemic control duration on platelet parameters pediatric population.The included 366 children, out which 144 (39.3%) were T1DM group 222 (60.6%) healthy group. count, mean volume (MPV), distribution width plateletcrit values recorded....
The present study aimed to evaluate choroidal changes and alternations within the structure of retina prior visible morphologic signs diabetic retinopathy (DR) in pediatric type 1 diabetes (T1D) cases. Two hundred six eyes 103 patients with T1D without DR 88 44 healthy controls were enrolled. They underwent a comprehensive ophthalmic examination optical coherence tomography evaluation. Choroidal thickness (ChT) measurements performed manually on macular peripapillary regions. There was no...
Lathosterolosis is a rare autosomal recessive congenital disease that occurs due to homozygous or compound heterozygous mutations in the sterol C5-desaturase (SC5D) gene. We report male patient with biallelic missense variant detected SC5D gene.An eight-month-old was referred department of paediatric neurology for status epilepticus. He had no remarkable dysmorphic features except micrognathia, ptotic ear and thin-stranded hair. Laboratory tests revealed an alanine aminotransferase level 502...
Objective: To report the neurologic prognosis and autoimmune complications of 16 cases childhood herpes simplex virus encephalitis. Methods: The study was conducted at Şanlıurfa Training Research Hospital, Turkey from June 2017 to August 2019. included pediatric patients aged between 6 months 17 years (median age 77.7 months) who were diagnosed with type 1 encephalitis by infectious disease neurology clinics. Patients followed using patient records, interviews clinic or via telephone....
Introduction:Vitamin D is known as a vitamin but also it acts prohormone and has many functions.The aim of this study to investigate the levels in pediatric patients with COVID-19. Materials Methods: A retrospective was performed tertiary education research hospital Istanbul, Turkey during period Marcht o April 2020.Children diagnosed symptomatic COVID-19 infection were included study.Demographic, clinical laboratory findings recorded from patient charts retrospectively.All investigated for...
Microcephaly, epilepsy and diabetes syndrome 1 (MEDS1) is a rare autosomal recessive disorder caused by defects in the immediate early response 3 interacting protein (
Introduction:The prevalence and association of type 1 diabetes mellitus (T1D) non-alcoholic fatty liver disease (NAFLD) have been explored; however, no study has examined parenchyma elasticity in pediatric T1D patients without NAFLD.Two-dimensional shear wave sonoelastography (2D-SWE) can effectively detect grade fibrosis diseases that be seen patients.The aim this was to analyze the 2D-SWE results children NAFLD identify any potential effects early.Methods: This prospective case-control...
<title>Abstract</title> Background Childhood obesity has become a major global health problem. Obesity is associated with problems, such as diabetes, hypertension, dyslipidemia, cardiovascular disease. also considered risk factor for Pseudotumor cerebri (PTS). The present study aimed to investigate the relationship between body mass index (BMI), and cerebrospinal fluid (CSF) pressure in patients pseudotumor cerebri. Methods A total of 48 children diagnosed PTS, who were aged < 18 years...
Childhood obesity has become a major global health problem. Obesity is associated with problems, such as diabetes, hypertension, dyslipidemia, cardiovascular disease. also considered risk factor for Pseudotumor cerebri (PTC). The present study aimed to investigate the relationship between body mass index (BMI), and cerebrospinal fluid (CSF) pressure in patients pseudotumor cerebri.
Studies which report cystatin C's (Cys-C) role in immunological disorders are increasing. However, data the pediatric age group is limited. In this study, we aimed to evaluate association between serum Cys-C levels and thyroid autoantibodies children adolescents diagnosed with euthyroid Hashimoto's thyroiditis.The patient was included 50 participants aged 3 18 years, control healthy matched for age, gender, body mass index. Patients hypothyroidism or taking any medication were not study....
What is already known on this topic?Hyperprolactinemia affects gonadal function in the adolescent.Cabergoline a useful treatment model for pituitary adenomas.Pituitary surgery macroadenomas may need some patients.Some drugs increase prolactin level.Macroprolactinemia one of causes hyperprolactinemia. study adds?Cabergoline an effective adolescent.There no difference term age between micro-and macroadenomas.Physicians should review surgical indications macroadenomas.Macroprolactinemia...
The aim of this study was to evaluate the demographic and clinical characteristics treatment outcomes children with Salmonella gastroenteritis.We retrospectively reviewed medical records pediatric patients aged between 1 month 18 years diagnosis gastroenteritis May 2015 December 2021.A total 172 diagnosed gastroenteritis, including 113 outpatients 59 hospitalized children, were included in study. There 95 (55.2%) males 77 (44.8%) females a median age 59.5 months (interquartile range [IQR]:...
Central precocious puberty (CPP) is one of the common reasons for referral to pediatric endocrinology. Magnetic resonance imaging (MRI) used rule out intracranial pathologies. However, there insufficient information in literature about bone marrow abnormalities on MRI CPP cases. The aim this study was evaluate apparent diffusion coefficient (ADC) values obtained from weight images (DWI) cranial structures and status sphenooccipital synchondrosis (SOS) CPP.MRI data 6-to 9-year-old girls with...
Introduction: Obesity is an increasing health problem in the whole world, and it has important inflammatory component related to insulin resistance (IR), hypertension, atherosclerosis some cancers. This study aims evaluate hematological parameters childhood obesity.Methods: Sixty-four obese 50 normal weight cases were included study. The physical examination features laboratory data of patients evaluated retrospectively from patient’s files. Laboratory tests, parameters, gender compared...