A5031162204- Tuberculosis Research and Epidemiology
- Diagnosis and treatment of tuberculosis
- Mycobacterium research and diagnosis
- Infectious Diseases and Tuberculosis
- Pneumonia and Respiratory Infections
- Pneumocystis jirovecii pneumonia detection and treatment
- Infectious Diseases and Mycology
- Immune responses and vaccinations
- Pharmacological Effects and Toxicity Studies
- Zoonotic diseases and public health
- Global Health and Surgery
- Health Systems, Economic Evaluations, Quality of Life
- COVID-19 Clinical Research Studies
- Global Maternal and Child Health
- Biosimilars and Bioanalytical Methods
- SARS-CoV-2 and COVID-19 Research
- Infectious Encephalopathies and Encephalitis
- Healthcare cost, quality, practices
- Quinazolinone synthesis and applications
- Venous Thromboembolism Diagnosis and Management
- Case Reports on Hematomas
- Inhalation and Respiratory Drug Delivery
- Antifungal resistance and susceptibility
- Research Data Management Practices
- Delphi Technique in Research
Associazione Italiana Vulvodinia Onlus
2018-2023
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2008-2020
International Flame Research Foundation
2019-2020
British Association for Immediate Care Scotland
2015
BASilar artery International Cooperation Study
2015
Associazione Italiana Pneumologi Ospedalieri
2013
Ospedale Eugenio Morelli
2003-2009
Laboratoire National de Référence
1999-2009
Fondazione Salvatore Maugeri
1997-2005
Bath Institute for Rheumatic Diseases
2000
Extensively Drug Resistant Tuberculosis (XDR-TB) is a very serious form of TB against which our treatment weapons have lost the majority of, if not all, their power
Currently, no information is available on the effect of resistance/susceptibility to first-line drugs different from isoniazid and rifampicin in determining outcome extensively drug-resistant tuberculosis (XDR-TB) patients, whether being XDR-TB a more accurate indicator poor clinical than resistant all anti-tuberculosis (TB) drugs. To investigate this issue, large series multidrug-resistant TB (MDR-TB) cases diagnosed Estonia, Germany, Italy Russian Federation during period 1999–2006 were...
Linezolid is used to treat patients with multidrug-resistant (MDR)/extensively drug-resistant (XDR)-tuberculosis (TB) cases, although clinical data on its safety, tolerability and efficacy are lacking. We performed a retrospective, nonrandomised, unblinded observational study evaluating the safety of linezolid at 600 mg q.d. or b.i.d. in MDR/XDR-TB treatment four European countries. Efficacy evaluation compared end-points 45 linezolid-treated against 110 linezolid-nontreated cases. Out 195...
World Tuberculosis Day, observed on 24 March each year, is the global call to raise awareness, celebrate successes and remind world that tuberculosis (TB) still number one killer among infectious causes of death [1]. TB a preventable curable disease, its control highly cost-effective health intervention. However, diagnostic delay inadequate treatment contribute severity mortality disease as well risk transmission development drug resistance. Despite fact disproportionately impacts low-...
ABSTRACT The characterization of Mycobacterium tuberculosis antigens inducing CD4 + T-cell responses could critically contribute to the development subunit vaccines for M. tuberculosis. Here we performed computational analysis by using epitope prediction software (known as TEPITOPE) predict promiscuous HLA-DR ligands in products mce genes proliferative T cells from patients with pulmonary selected peptides displaying binding vitro led us identification a peptide that induced proliferation...
Tuberculosis (TB) is one of the oldest diseases known to affect humanity, and still a major public health problem. It caused by bacillus Mycobacterium tuberculosis (MT), isolated in 1882 Robert Koch. Until 1950s, X rays were used as cheap method diagnostic screening together with tuberculin skin sensitivity test. In diagnosis treatment TB, an important role was also played surgery. The late Nineteenth century saw introduction sanatorium, which proved be first useful measures against TB....
Villa Marelli Institute (VMI), Niguarda Ca'Granda Hospital, Milan, Italy.A recent report on the fatal side effects of isoniazid preventive therapy (IPT) from United States has re-ignited discussion safety this intervention.To evaluate IPT feasibility, treatment completion and adverse events (AE) their determinants under field conditions.Data consecutive subjects undergoing at VMI were recorded in an electronic database 1992 to 2009. Logistic regression analysis was performed detect AE...
The increased incidence of drug-resistant TB is a major challenge for effective control. Limited therapeutic options and poor treatment outcomes DR-TB may increase drug-resistance rates. objective the study to retrospectively compare MDR-TB pre-XDR-TB regimens in two large reference centres Italy from January 2000 2015.A retrospective, multicentre was conducted at Regional Reference Centre Villa Marelli Institute (Milan) Center HIV-TB, Eugenio Morelli Hospital (Sondalo). supra-national...