A5030992953- RNA Interference and Gene Delivery
- Nanoplatforms for cancer theranostics
- Dendrimers and Hyperbranched Polymers
- interferon and immune responses
- Inflammasome and immune disorders
- Advanced biosensing and bioanalysis techniques
- Virus-based gene therapy research
- Organ Transplantation Techniques and Outcomes
- Renal Transplantation Outcomes and Treatments
- Heme Oxygenase-1 and Carbon Monoxide
- Antimicrobial Peptides and Activities
- Sulfur Compounds in Biology
State Key Laboratory of Polymer Physics and Chemistry
2024
Chinese Academy of Sciences
2020-2024
Changchun Institute of Applied Chemistry
2020-2024
Ludwig-Maximilians-Universität München
2017
Center for NanoScience
2017
Melanoma, as the most aggressive and treatment-resistant skin malignancy, is responsible for about 80% of all cancer mortalities. Prone to invade into dermis form distant metastases significantly reduce patient survival rate. Therefore, early treatment melanoma in situ or timely blocking deterioration critical. In this study, a sulfur dioxide (SO
Here, we report novel lipo-oligoaminoamide nanoformulations for targeted intracellular protein delivery. Formulations are generated by first bioreversibly conjugating a sequence-defined amphiphilic lipo-oligomer 728 to the cargo via disulfide bonds, followed formulation of formed 728-SS-protein conjugate with different helper lipids in various compositions. The triblock oligoaminoamide contains cysteines reversible covalent conjugation and cross-link-stabilization nanoparticles, polyethylene...