Kristen E. Limbach

ORCID: 0000-0002-2078-2025
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About
Contact & Profiles
Research Areas
  • Neuroendocrine Tumor Research Advances
  • Lung Cancer Research Studies
  • Neuroblastoma Research and Treatments
  • Pancreatic and Hepatic Oncology Research
  • Cancer Cells and Metastasis
  • Breast Cancer Treatment Studies
  • Cancer Genomics and Diagnostics
  • Cultural Competency in Health Care
  • Bariatric Surgery and Outcomes
  • Gestational Trophoblastic Disease Studies
  • Cancer Risks and Factors
  • Intraperitoneal and Appendiceal Malignancies
  • Global Cancer Incidence and Screening
  • Opioid Use Disorder Treatment
  • Brain Metastases and Treatment
  • Anesthesia and Pain Management
  • Metastasis and carcinoma case studies
  • Colorectal Cancer Screening and Detection
  • Pain Management and Opioid Use
  • Diet and metabolism studies
  • Cardiac, Anesthesia and Surgical Outcomes
  • 3D Printing in Biomedical Research
  • Health and Medical Research Impacts
  • Innovations in Medical Education
  • Global Health Workforce Issues

City Of Hope National Medical Center
2023-2024

Tulane University
2024

City of Hope
2022-2023

Beckman Research Institute
2022

American Association of Endocrine Surgeons
2022

University of Portland
2021

Oregon Health & Science University
2018-2021

University School
2013-2014

Case Western Reserve University
2012-2014

Metastatic progression defines the final stages of tumor evolution and underlies majority cancer-related deaths. The heterogeneity in disseminated cell populations capable seeding growing distant organ sites contributes to development treatment resistant disease. We recently reported identification a novel tumor-derived population, circulating hybrid cells (CHCs), harboring attributes from both macrophages neoplastic cells, including functional characteristics important metastatic spread....

10.1038/s41598-021-93053-7 article EN cc-by Scientific Reports 2021-07-01

Bone metastases from gastroenteropancreatic neuroendocrine neoplasms (GEPNENs) have been associated with poor prognosis, but it is unclear whether patients concurrent bone who receive liver-directed therapy (LDT) would derive survival benefit. The California Cancer Registry dataset, merged data the Office of Statewide Health Planning and Development, was used to perform a retrospective study GEPNENs metastatic both liver between 2000 2012. A total 203 were identified. Of these, 14.8%...

10.3390/jcm12247646 article EN cc-by Journal of Clinical Medicine 2023-12-13

Background: Although survival outcomes for neuroendocrine liver metastases (NETLM) are improved with liver-direct therapies (LDT), including hepatic debulking and nonsurgical trans-arterial embolization, the benefit is less established in setting of concurrent extrahepatic disease (EHD). We performed a population-based study to characterize rates LDT being NETLM EHD patients whether associated outcomes. Methods: Patients were identified using California Cancer Registry database merged data...

10.3390/jcm13174983 article EN Journal of Clinical Medicine 2024-08-23

Abstract Purpose Renal and hematological toxicity are side effects dose-limiting factors of Peptide Receptor Radionuclide Therapy (PRRT). We aimed to assess the changes in renal function associations with survival neuroendocrine tumor (NET) patients treated PRRT. Methods A retrospective cohort 448 NET either 177 Lu-DOTATATE or 90 Y-DOTATOC were followed for function. was assessed by monitoring serum creatinine, blood urea nitrogen estimated glomerular filtration rate. Hematological...

10.1007/s00432-024-06020-w article EN cc-by Journal of Cancer Research and Clinical Oncology 2024-11-02

Women younger than 30 make up only 1% of those diagnosed with breast cancer,1 but a number studies have demonstrated that cancer in young women has more aggressive biology and is associated poorer outcomes postmenopausal women.2-4 This may part be due to higher frequency phenotypes,5-7 age itself also been identified as an independent indicator poor prognosis.6 Given this prognosis, risk factors for under 40 remain topic interest the literature, so far vary significantly from women.8...

10.1111/tbj.13783 article EN The Breast Journal 2020-02-14

Abstract Metastatic progression defines the final stages of tumor evolution and underlies majority cancer-related deaths. The heterogeneity in disseminated cell populations capable seeding growing distant organ sites contributes to development treatment resistant disease. We recently reported identification a novel tumor-derived population, circulating hybrid cells (CHCs), harboring attributes from both macrophages neoplastic cells, including functional characteristics important metastatic...

10.1101/2021.03.11.434896 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2021-03-12

: Promotion of surgical technology relies on the availability financial and infrastructural resources, particularly as traditional sources funding, such National Institutes Health (NIH) grants, have waned in recent decades. Resources for support depend stage development context which idea is being studied. For technologies evaluated by clinical trials, insurance reimbursement may assist with Affordable Care Act (ACA) has mandated that routine costs enrollment trials be covered health...

10.21037/ls-22-5 article EN Laparoscopic Surgery 2022-04-01
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