- Pancreatic and Hepatic Oncology Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Gastric Cancer Management and Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Colorectal Cancer Screening and Detection
- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Treatments and Studies
- Gastrointestinal Tumor Research and Treatment
- Gallbladder and Bile Duct Disorders
- Cancer Genomics and Diagnostics
- Neuroendocrine Tumor Research Advances
- Esophageal Cancer Research and Treatment
- Renal cell carcinoma treatment
- Gastrointestinal disorders and treatments
- Colorectal and Anal Carcinomas
- Esophageal and GI Pathology
- Liver Disease Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Sarcoma Diagnosis and Treatment
- Cancer Cells and Metastasis
- Economic and Financial Impacts of Cancer
- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Genetic factors in colorectal cancer
- Metastasis and carcinoma case studies
Yale University
2020-2025
Yale Cancer Center
2021-2024
Smilow Cancer Hospital
2020-2023
Yale New Haven Hospital
2020-2023
Hirslanden Klinik St. Anna
2022
Klinik Hirslanden
2022
Oregon Health & Science University
2012-2021
OHSU Knight Cancer Institute
2018-2021
University of Portland
2013-2020
Memorial Sloan Kettering Cancer Center
1998-2019
To report the patterns of disease and postmetastasis survival for patients with pulmonary metastases from soft tissue sarcoma in a large group treated at single institution. Clinical factors that influence are analyzed.For sarcoma, lungs most common site metastatic disease. Although commonly arise primary tumors extremities, they may almost any or histology. date, resection has been only effective therapy sarcoma.From July 1982 to February 1997, 3149 adult were admitted Memorial...
Peripheral blood MФ–cancer cell fusion hybrids identified in cancer patients correlate with disease stage and overall survival.
BACKGROUND Despite optimal multimodality limb-sparing therapy for extremity soft tissue sarcoma (STS), a significant number of patients develop distant metastasis. The objective this study was to analyze patterns metastatic disease and define prognostic factors survival in large group followed prospectively at single institution. METHODS Between July 1, 1982, June 30, 1996, all adult admitted the Memorial Sloan-Kettering Cancer Center with primary were treated followed. Patients who...
Black-white disparities exist in receipt of recommended medical care, including colorectal cancer treatment. This retrospective cohort study examines the degree to which health systems (e.g., physician, hospital) factors explain black-white colon care.Data from Surveillance, Epidemiology, and End Results program; Medicare claims; American Medical Association Masterfile; hospital surveys were linked examine chemotherapy after stage III resection among 5294 elderly (> or = 66 years age) black...
<h3>Importance</h3> While increased adherence to colorectal cancer (CRC) screening guidelines in the US has been associated with significant reductions incidence individuals aged 50 years and older, of CRC among those younger than steadily increasing. Understanding survival early-onset compared older is fundamental informing treatment approaches understanding unique biological distinctiveness within CRC. <h3>Objective</h3> To characterize overall for <h3>Design, Setting, Participants</h3>...
Certain factors, such as race or age, are known to be associated with variation in initiation of adjuvant chemotherapy for stage III colon cancer, but little is about what factors completion therapy. To determine whether predictors also predict completion, we analyzed Surveillance, Epidemiology, and End Results (SEER) program data linked Medicare claims. We investigated mortality a means testing the validity measure that created.We studied 3193 cancer patients whose diagnosis was recorded...
Although numerous studies have demonstrated an association between surgical volume and improved outcome in cancer surgery, the specific structures mechanisms of care that are associated with lead to outcomes remain poorly defined. We hypothesize there modifiable surgeon hospital characteristics explain observed volume-outcome relationships.Retrospective cohort study.Surveillance, Epidemiology, End Results registry areas.Patients aged 66 years older, diagnosed surgically treated for stage I,...
To describe unplanned procedures following colorectal cancer surgery that might be used as intermediate outcome measures, and to determine their association with mortality length of stay.Variation in the quality surgical care, especially for common illnesses like cancer, has received increasing attention. Nonfatal complications resulting procedural interventions are likely play a role poor outcomes but have not been well explored.Cohort analysis 26,638 stage I III patients 1992 1996...
Black patients with rectal cancer are considerably less likely than white to receive adjuvant therapy. We examined the hypothesis that lower treatment rate for blacks is due underreferral medical and radiation oncologists. used 1992–1999 Surveillance, Epidemiology, End Results–Medicare data identify elderly (≥66 years of age) who had been hospitalized resection stage II or III (n = 2716). χ 2 tests examine associations between race 1) consultation an oncologist 2) receipt then logistic...
Racial disparities have been demonstrated in many facets of health care, but a comprehensive understanding who is most at risk for substandard surgical care gastrointestinal tract cancers lacking.To examine racial quality patients with cancers.This retrospective cohort study cancer included the US population as captured National Cancer Database diagnosis from January 1, 2004, to December 31, 2017. Participants 565 124 adults underwent resection cancers. Data were analyzed June 21 23,...
Purpose Pathologic complete response (pCR) after neoadjuvant therapy for locally advanced esophageal adenocarcinoma is associated with improved survival. The Southwest Oncology Group designed a trimodality, phase II, single-arm trial objectives of achieving pCR rate 40% prospective exploratory analyses intratumoral molecular markers postulated to affect and Patients Methods clinically staged II or III received oxaliplatin 85 mg/m 2 on days 1, 15, 29; protracted-infusion fluorouracil (PI-FU)...
Abstract Introduction Hepatic artery infusion pump (HAIP) chemotherapy is a specialized therapy for patients with unresectable colorectal liver metastases (uCRLM). Its effectiveness was demonstrated from high volume center, uncertainty regarding the feasibility and safety at other centers. Therefore, we sought to assess of HAIP management uCRLM Methods We conducted multicenter retrospective cohort study treated January 2003 December 2017 six North American centers initiating program....
Abstract BACKGROUND This study examined elderly stage II and III rectal cancer patients' adjuvant chemoradiation therapy adherence, trends in adherence over time, the relation of levels to mortality. METHODS The authors studied 2886 patients who had surgical resection appeared 1992–1999 linked SEER‐Medicare claims data. compared measures radiation chemotherapy receipt completion between patients. Adjusted risk cancer‐related 5‐year mortality was calculated by multivariate logistic regression...