A5058434910- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Stroke Rehabilitation and Recovery
- Muscle activation and electromyography studies
- Zebrafish Biomedical Research Applications
- Pancreatic and Hepatic Oncology Research
- Economic and Financial Impacts of Cancer
- COVID-19 Impact on Reproduction
- Botulinum Toxin and Related Neurological Disorders
- Sex and Gender in Healthcare
- Spinal Dysraphism and Malformations
- Diet and metabolism studies
- Pain Mechanisms and Treatments
- Urinary Bladder and Prostate Research
- Appendicitis Diagnosis and Management
- Hernia repair and management
- Adipose Tissue and Metabolism
- Colorectal Cancer Surgical Treatments
- Urinary Tract Infections Management
- Science, Research, and Medicine
- BRCA gene mutations in cancer
- Intestinal and Peritoneal Adhesions
- Pelvic floor disorders treatments
- Cerebrospinal fluid and hydrocephalus
- COVID-19 Clinical Research Studies
Yale University
2023-2025
VA Connecticut Healthcare System
2024
United States Department of Veterans Affairs
2024
Donald & Barbara Zucker School of Medicine at Hofstra/Northwell
2019-2020
Northwell Health
2020
Burke Medical Research Institute
2016-2017
We compared the outcome of COVID-19 in immunosuppressed solid organ transplant (SOT) patients to a naïve population. In total, 10 356 adult hospital admissions for from March 1, 2020 April 27, were analyzed. Data collected on demographics, baseline clinical conditions, medications, immunosuppression, and course. Primary was combined death or mechanical ventilation. assessed association between primary prognostic variables using bivariate multivariate regression models. also endpoint SOT an...
802 Background: Health-related social conditions affect cancer outcomes. Gastrointestinal cancers (GIC) comprise a large proportion of diagnosed in the United States. We hypothesized that diagnosis GIC negatively impacts Social Determinants Health (SDOH) and perceived health (PH). Methods: Prospectively collected data from The All Us database was queried for patients who completed SDOH PH surveys. Healthy, non-cancer (NC) participants were matched to based on age, race, sex, deprivation...
Abstract Background Appendiceal tumors represent a range of histologies that vary in behavior. Recommendations for treatment with appendectomy versus right hemicolectomy (RHC) different tumor types are evolving and sometimes conflicting. This study sought to characterize variation the United States around surgical major appendiceal over time describe differences outcomes based on procedure. Methods Patients diagnosed goblet cell adenocarcinoma (GCA), mucinous adenocarcinoma, neuroendocrine...
Background. Rodents are the primary animal model of corticospinal injury and repair, yet current behavioral tests do not show large deficits after observed in humans. Forearm supination is critical for hand function highly impaired by both humans rats. Current rodent forelimb measure this movement. Objective. To determine if quantification rats reveals large-scale functional loss partial recovery injury. Methods. We developed a knob device that quantifies using automated objective methods....
The NIH policy on sex as biological variable (SABV) emphasized the importance of sex-based differences in precision oncology. Over 50% clinically actionable oncology genes are sex-biased, indicating drug efficacy. Research has identified non-reproductive cancers, highlighting need for comprehensive cancer data. We therefore developed OncoSexome, a multidimensional knowledge base describing (https://idrblab.org/OncoSexome/) across four key topics: antineoplastic drugs and responses (SDR),...
Tasks that accurately measure dexterity in animal models are critical to understand hand function. Current rat behavioral tasks largely use video analysis of reaching or food manipulation. While these easy implement and robust across disease models, they subjective laborious for the experimenter. Automating traditional creating new automated can make more efficient, objective, quantitative. Since rats less dexterous than primates, central nervous system (CNS) injury produces subtle deficits...
Rodent tests of function have advanced our understanding movement, largely through the human training and testing manual assessment. Tools such as reaching grasping a food pellet been widely adopted because they are effective simple to use. However, these tools time-consuming, subjective, often qualitative. Automation training, testing, assessment has potential increase efficiency while ensuring tasks objective quantitative. We detail new methods for automating rodent forelimb tests,...
Introduction Colonic perforation often requires emergent intervention and carries high morbidity mortality. The objective of this study was to determine whether nonclinical factors, such as transition care from outpatient facilities inpatient settings, are associated with increased risk mortality in patients who underwent surgical for colonic perforation. Materials Methods Using the 2006-2015 ACS National Surgical Quality Improvement Program database, we identified adult partial colectomy...
Tasks that accurately measure dexterity in animal models are critical to understand hand function. Current rat behavioral tasks largely use video analysis of reaching or food manipulation. While these easy implement and robust across disease models, they subjective laborious for the experimenter. Automating traditional creating new automated can make more efficient, objective, quantitative. Since rats less dexterous than primates, central nervous system (CNS) injury produces subtle deficits...
Introduction Surgical intervention is important in reducing morbidity and mortality among patients admitted for small bowel obstruction (SBO). Patient-specific variables such as age comorbidities are risk factors adverse outcomes after surgery SBO. However, the effect of weekend admission on has not been well delineated literature. Our aim was to determine whether affects length stay (LOS) who were SBO managed operatively. Materials Methods Using 2006-2012 Nationwide Inpatient Sample (NIS)...