- Heavy Metal Exposure and Toxicity
- Fluoride Effects and Removal
- Air Quality and Health Impacts
- Selenium in Biological Systems
- Nutrition and Health Studies
- Trace Elements in Health
- Bone and Dental Protein Studies
- Antioxidant Activity and Oxidative Stress
- Vitamin C and Antioxidants Research
- Human Health and Disease
- Electromagnetic Fields and Biological Effects
- Liver Disease Diagnosis and Treatment
- Exercise and Physiological Responses
- Medicinal plant effects and applications
- Biochemical effects in animals
- Coenzyme Q10 studies and effects
- Sperm and Testicular Function
- Carcinogens and Genotoxicity Assessment
- Effects and risks of endocrine disrupting chemicals
- Thyroid Disorders and Treatments
- Asthma and respiratory diseases
- Biochemical Acid Research Studies
- Folate and B Vitamins Research
- Cardiovascular Function and Risk Factors
- Digestive system and related health
Medical University of Silesia
2012-2021
Górnośląskie Centrum Medyczne
2001-2018
University of Silesia in Katowice
2007-2018
Wojewódzki Szpital Specjalistyczny nr 5 im. św. Barbary w Sosnowcu
2018
Silesian University in Opava
2006-2010
Silesian Center for Heart Disease
2004-2006
Społeczna Akademia Nauk
2004
Śląska Wyższa Szkoła Informatyczno-Medyczna
2000-2002
Abstract The aim of this study was to assess the influence cisplatin and an extremely low frequency electromagnetic field (ELF‐EMF) on antioxidant enzyme activity lipid peroxidation ratio, as well level DNA damage reactive oxygen species (ROS) production in AT478 carcinoma cells. Cells were cultured for 24 72 h culture medium with cisplatin. Additionally, cells irradiated 50 Hz/1 mT ELF‐EMF 16 min using a solenoid source ELF‐EMF. amount ROS, superoxide dismutase (SOD) isoenzyme activity,...
Abstract Background Alterations of the immune system are now believed to play crucial role in pathogenesis atherosclerosis. The aim this study was analysis soluble forms selectin‐P and interleukin‐8 levels patients with different form coronary heart disease. Materials methods: In took part 18 stable disease, 20 unstable disease 15 healthy persons from control group. Soluble were measured EDTA plasma use enzyme immunoassay ELISA. Results level significantly higher comparison ( P ≤ 0·01)...
Background. The aim of study was to determine relationships between functional capacity (NYHA class), left ventricle ejection fraction (LVEF), hemodynamic parameters, and biomarkers redox state inflammation in patients with dilated cardiomyopathy (DCM). Methods . DCM (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn>109</mml:mn></mml:math>, aged<mml:math...
The aim of the study was to determine total oxidant status (TOS) and evaluate influence oxidative stress on sperm quality in fertile males. population consisted 55 Based seminal plasma TOS value, subjects were divided into two subgroups: a group with low (TOS-L) high (TOS-H) value. Comparing TOS-H TOS-L group, we found poorer motility group. We lower antioxidant capacity values activity levels majority determined superoxide dismutase, glutathione peroxidase, glutathione-S-transferase...
The aim of the study was to evaluate parameters oxidative stress and antioxidant defense in relation levels proinflammatory cytokines chemokines patients diagnosed with oligozoospermia asthenozoospermia. Based on basic spermogram, examined group ( n = 243) divided into three groups: oligospermic (sperm count less than 15 × 10 6 /ml) consisting 152 men, astenozoospermic (less 40% progressively moving sperm cells) 142 oligoastenozoospermic (both criteria met) 90 men. control consisted 103...
Abnormalities in the oxidative and antioxidant states causing stress were both found heart failure (HF) of various aetiologies atherosclerosis. The goals study as follows: comparison parameters (OSP) ischaemic cardiomyopathy (ICM) (n = 479) nonischaemic (nICM) 295) patients; assessment relationships OSP with functional capacity (NYHA class), maximal oxygen consumption (max.O2), left ventricle ejection fraction (LVEF), NT-proBNP concentration; determination mutual relations subgroups patients...
The study population included healthy men and hypertensive employees of zinc lead steelworks in the south Poland. Workers exposed to (n=137) were divided into two groups: first with low exposure (LL) mean blood (PbB) 25-40 μg/dL second one PbB over 40 (HL group). administration workers (n=35) control group. Evaluation lipids oxidative changes cholesterol estimated samples. No significant concentration 7-ketocholesterol (cholesterol, HDL, LDL, triglycerides) found. Lipid peroxidation (LP) was...
This study aimed to compare the influence of lead on non-enzymatic antioxidant defenses and levels chemokines in workers subchronically chronically exposed lead.The population was divided into three groups. The first group consisted male for 40 ± 3.2 days, while second included lead. third a control group.The uric acid bilirubin were significantly higher after subchronic exposure compared baseline by 22 35 %, respectively. Similarly, values total capacity (TAC), oxidant status (TOS),...
The aim of the study was to investigate influence occupational lead (Pb) exposure on lipid peroxidation, protein carbonylation, and plasma viscosity in workers. examined group included 283 healthy male employees manufacturing facilities using zinc Pb. mean blood concentrations Pb protoporphyrin as well urine δ-aminolevulinic acid levels were used markers for group. Taking into account obtained values level, divided three subgroups. When comparing control with subgroups, significantly...
Context and objective. The aim of the study was to investigate whether treatment with N-acetylcysteine (NAC) is able restore erythrocyte glutathione (GSH) content in workers exposed lead. Additionally, we measured leukocyte activities GSH-related enzymes, such as reductase (GR), glutathione-S-transferase (GST), glucose-6-phosphate dehydrogenase (G6PD), estimated influence NAC administration on oxidative stress intensity, which lipofuscin (LPS) level erythrocytes. Methods. population...