A5033136546- Essential Oils and Antimicrobial Activity
- Trypanosoma species research and implications
- Bioactive Compounds and Antitumor Agents
- Traditional and Medicinal Uses of Annonaceae
- Plant Pathogens and Fungal Diseases
- Venomous Animal Envenomation and Studies
- Research on Leishmaniasis Studies
- Pharmaceutical and Antibiotic Environmental Impacts
- Inhalation and Respiratory Drug Delivery
- Nematode management and characterization studies
- Effects and risks of endocrine disrupting chemicals
- Pneumonia and Respiratory Infections
- Forensic Entomology and Diptera Studies
- Polyomavirus and related diseases
- Bacterial Infections and Vaccines
- Plant Diversity and Evolution
- Fermentation and Sensory Analysis
- Antifungal resistance and susceptibility
- Diptera species taxonomy and behavior
- Mycotoxins in Agriculture and Food
- Phytoplasmas and Hemiptera pathogens
- Sesquiterpenes and Asteraceae Studies
- Toxic Organic Pollutants Impact
- Insect behavior and control techniques
- Bee Products Chemical Analysis
Instituto de Investigaciones Científicas y Servicios de Alta Tecnología
2014-2025
City of Knowledge
2014-2025
Secretaría Nacional de Ciencia, Tecnología e Innovación
2025
Acharya Nagarjuna University
2016-2023
Universidad de Panamá
2020-2021
Xunta de Galicia
2012
Universidad de La Laguna
1994
Toads in the family Bufonidae contain bufadienolides their venom, which are characterized by chemical diversity and high pharmacological potential. American trypanosomiasis is a neglected disease that affects an estimated 8 million people tropical subtropical countries. In this research, we investigated composition antitrypanosomal activity of toad venom from Rhinella alata collected Panama. Structural determination using mass spectrometry (MS) nuclear magnetic resonance (NMR) spectroscopy...
Plinia cerrocampanensis is an endemic plant of Panama. The leaf essential oil this has shown antibacterial activity. However, anti-malarial activity and chemical profiling by HS-SPME-GC-MS have not been reported before. Anti-malarial the (EO) was evaluated in vitro against chloroquine-sensitive HB3 chloroquine-resistant W2 strains Plasmodium falciparum. Synergistic effect chloroquine EO on parasite growth calculating combination index. A methodology involving headspace solid phase...
Invasive infections caused by non-type b encapsulated Haemophilus influenzae have increased recently. Because capsule is a major virulence factor, capsulation of 62 recently isolated non–serotype strains was examined. Repeated serotyping confirmed only 69.0% isolates. The combination slide agglutination and cap genotyping 78.9% type a, 100% e, 86.4% f strains. Seven nonencapsulated may lost through homologous recombination. Three that could not be serotyped or genotyped failed to hybridize...
Current agrochemicals used in crop farming mainly consist of synthetic compounds with harmful effects on the environment and human health. Crop-associated fungal endophytes, which play many ecological roles including defense against pathogens, represent a promising source for bioactive ecologically safer molecules agrochemical discovery. The methanolic extract endophyte Menisporopsis sp. LCM 1078 was evaluated vitro plant pathogens Boeremia exigua, Calonectria variabilis, Colletotrichum...
SummaryThe in vitro activity of fluconazole, itraconazole and ketoconazole against 625 Candida yeast strains from patients treated at the University Hospital Canaries, by means a micromethod dilution broth enriched with Yeast Nitrogen Base (YNB), buffered to pH 7, has been assessed.Species distribution was as follows: albicans (388), tropicalis (84), glabrats patapsilosis (69).Our results show 10.0% 8.8% C. resistant respectively, 1.8% ketoconazole; 39.5% were itraconazole, 34.5% fluconazole...
Effectiveness of botanical treatments has been recognized by many, but scientific validation on the beneficial use plants is scarce. Nopalea pads are probably native to Mexico or Central America and used for human consumption medicinal purposes. In this study, in vitro antibacterial antifungal activities fresh dried cochenillifera (NC) were investigated. MICs NC hexanic, chloroformic ethanolic fractions against C. albicans 250, 250 3.9 mg mL-1 respectively; Salmonella enterica var....
The comparison of SPME fiber coatings, and optimization temperature time extraction for headspace solid phase microextraction (HS-SPME) volatile organic compounds (VOCs) present in Pouteria sapota (sapote mamey) fruits is presented. PDMS/DVB coating afforded the highest efficiency. conditions were optimized by using Doehlert experimental design. By HS-SPME method, 21 VOCs identified, which include mainly terpenoids esters, followed aromatic hydrocarbons, aldehydes, alcohols ketones. most...
Collectively, leishmaniasis and Chagas disease cause approximately 8 million cases more than 40,000 deaths annually, mostly in tropical subtropical regions. The current drugs used to treat these diseases have limitations many undesirable side effects; hence, new with better clinical profiles are needed. Fungal endophytes associated plants known produce a wide array of bioactive secondary metabolites, including antiprotozoal compounds. In this study, we analyzed endophytic fungal isolates
Rhinella alata is a small terrestrial bufonid that occurs in Ecuador, Colombia, and Panama. Between January 2014 October 2015, we inspected 339 R. from Panama report myiasis eight of these toads. All infested toads were male presented with mobile dark fly larvae visible beneath the ventral skin. At necropsy, identified as belonging to family Sarcophagidae (flesh flies). Flesh flies have been variously considered predators, parasitoids, parasites anurans. There are at least four species flesh...
Amphibians are widely known as a prolific source of bioactive metabolites. In this work we isolated and characterized compounds with antiparasitic activity from the oocytes toad Rhinella alata collected in Panama. Bio-guided isolation structural elucidation was carried out using chromatographic spectroscopic techniques. The organic crude extract subjected to solid phase extraction followed by HPLC purification fraction vitro against Trypanosoma cruzi trypomastigotes. Seven steroids (1-7)...
Amphibians are widely known as a prolific source of bioactive metabolites. In this work, we isolated and characterized compounds with antiparasitic activity from the oocytes toad Rhinella alata collected in Panama. Bio-guided isolation structural elucidation were carried out using chromatographic spectroscopic techniques, respectively. The organic extract was subjected to solid phase extraction followed by HPLC purification fraction vitro against Trypanosoma cruzi trypomastigotes. Seven...